Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 170757864

GI number: 170757864

Start: 3912507

End: 3912941

Strand: Reverse

Name: fabZ

Synonym: CLD_0889

Alternate gene names: 170757864

Gene position: 3912941-3912507 (Counterclockwise)

Preceding gene: 170756252

Following gene: 170756739

Centisome position: 98.86

GC content: 31.26

Gene sequence:

>435_bases
ATGGAGAAATTTTTAGATATAAATGAAATAAAAAGAATTATTCCACATAGATATCCATTCTTATTAGTAGATAAAATAAC
TGAACTAGAAGAGGGAAAAAGTGCAGTTGGATATAAAAATGTTACAGTTAATGAATATTTTTTTAATGGACATTTCCCTG
AAGAACCAGTAATGCCTGGAGTTCTAATTATAGAAGCTTTAGCACAGGTTGGAGCCGTAGCTATTTTAAGTAAAGAAGAA
TTTAAAGGAAAAATAGCTTATTTTGGTGGAATAAATAAAGCGAAGTTTAGAAAAAAAGTAGTACCTGGAGATGAATTAAA
GCTTAGTATAGAACTCACTAAGATAAAAGGTGTTGCAGGAGTGGGTAAAGCTGTAGCTACTGTAGATGGGAAGGTAGCTG
CGGAAGCGGAATTATTATTTGTAATAGGAAAATAA

Upstream 100 bases:

>100_bases
GGAGAAATAGTAGCTGTATTGGGAGAAAACGGTGAAATGGTTCAATATGGAGAAGCTTTATTTAAGATAAAGCCACTATA
GTGAAAAAGGAGAAATTTTA

Downstream 100 bases:

>100_bases
ACTTATAAAAAGTAGAGAGGGAGAAGATAGCAGTGTTTAAAAAAATACTTGTGGCTAATAGAGGTGAGATTGCTGTTAGA
ACAATTAGAGCCTGTAGAGA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MEKFLDINEIKRIIPHRYPFLLVDKITELEEGKSAVGYKNVTVNEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEE
FKGKIAYFGGINKAKFRKKVVPGDELKLSIELTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK

Sequences:

>Translated_144_residues
MEKFLDINEIKRIIPHRYPFLLVDKITELEEGKSAVGYKNVTVNEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEE
FKGKIAYFGGINKAKFRKKVVPGDELKLSIELTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK
>Mature_144_residues
MEKFLDINEIKRIIPHRYPFLLVDKITELEEGKSAVGYKNVTVNEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEE
FKGKIAYFGGINKAKFRKKVVPGDELKLSIELTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=46.7153284671533, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 15790; Mature: 15790

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKFLDINEIKRIIPHRYPFLLVDKITELEEGKSAVGYKNVTVNEYFFNGHFPEEPVMPG
CCCCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCH
VLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDELKLSIELTKIKGVAG
HHHHHHHHHHCEEEEEECHHCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEEEEECCCCC
VGKAVATVDGKVAAEAELLFVIGK
CCCEEEECCCCEECCEEEEEEEEC
>Mature Secondary Structure
MEKFLDINEIKRIIPHRYPFLLVDKITELEEGKSAVGYKNVTVNEYFFNGHFPEEPVMPG
CCCCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCH
VLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDELKLSIELTKIKGVAG
HHHHHHHHHHCEEEEEECHHCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEEEEECCCCC
VGKAVATVDGKVAAEAELLFVIGK
CCCEEEECCCCEECCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA