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The map label for this gene is wtpB [H]

Identifier: 170757795

GI number: 170757795

Start: 1235607

End: 1236470

Strand: Direct

Name: wtpB [H]

Synonym: CLD_3453

Alternate gene names: 170757795

Gene position: 1235607-1236470 (Clockwise)

Preceding gene: 170756755

Following gene: 170754910

Centisome position: 31.22

GC content: 26.39

Gene sequence:

>864_bases
GTGAAAGAAAAGATGAAACCTTATATATTATTATTACCAGTTACAATAATAATAGTTTCTATATTAGGAGTAGGAATAAT
AAATTGCCTAAGTCAAAGCTTAGGCTATTTTCCTACAGTGGGCTTGAATGAAATTACACTTAAATACTATAAAGAGATTC
TAACTTCTAGGGAATTTGTAGAATCTTTAAAGTTTAGTTTATTTACCTGTATTTTATCTTCTTTAATAGCTGAATTTATT
GGTGTTGTTTTAGCTTATATTATATTTACGCATAAGAAGAGGAGTAAAATTTTAGATGTTATATATAAGATACCTATAAT
AATACCTCATACTGTTGCAGTTTTACTTATTATAAATATGCTATCACAAAATGGAATATTGGCTAGAATACTATATAATT
TAGGATTAATAAGTTCTAGAAATATTTTTCCTAATCTTATAATGGATAAATGGGGAATAGGTATAATAATAACTTATGTA
TGGAAGGAGATACCTTTTATTATACTGGTTATCTATGCTGTATTAACTAATATAGATGAAAAAATGTGGTATCTTTCAAG
AACACTGGGGGCTAGTAAAACACAAACTTTTTTTTATGTCATATTTCCTATGCTTGTGCCCTCTATTTTATCTTCTTTTA
TAATAATCTTTGCTTTTTCTTTTGGAGCTTTTGAGGTACCTTATTTGTTAGGACCAACTACTCCAAAATCACTTCCAGTT
AAGGCATATATAGAATATTCTAATCCAGATTTAACCAATAGGCCTTATGCTATGGTAATAAATACTATACTTATAGTTAT
ATCGACCTTCTTAATAATTTTGTATAGAAAATCTTTGGATATTTTTAAAAAAGAATCTAAATAA

Upstream 100 bases:

>100_bases
CAAAGTGAATTGCTACCACACAGATTACCAGAGTTGCCAGCAGAATTAGTACCAATTATAGAAAAAATATGGCAAGAAAA
TATACCAGGAGATAAATAAA

Downstream 100 bases:

>100_bases
TAAATAGGAAAGGAAAATATTATAAATGAGAAATAAAAAAATAATTTCTAATATAATAATATATAGCTTCGCATTTTTCT
TTCTATTTCCTATAATAATA

Product: ABC transporter, permease protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKEKMKPYILLLPVTIIIVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEILTSREFVESLKFSLFTCILSSLIAEFI
GVVLAYIIFTHKKRSKILDVIYKIPIIIPHTVAVLLIINMLSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYV
WKEIPFIILVIYAVLTNIDEKMWYLSRTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLPV
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFKKESK

Sequences:

>Translated_287_residues
MKEKMKPYILLLPVTIIIVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEILTSREFVESLKFSLFTCILSSLIAEFI
GVVLAYIIFTHKKRSKILDVIYKIPIIIPHTVAVLLIINMLSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYV
WKEIPFIILVIYAVLTNIDEKMWYLSRTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLPV
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFKKESK
>Mature_287_residues
MKEKMKPYILLLPVTIIIVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEILTSREFVESLKFSLFTCILSSLIAEFI
GVVLAYIIFTHKKRSKILDVIYKIPIIIPHTVAVLLIINMLSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYV
WKEIPFIILVIYAVLTNIDEKMWYLSRTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLPV
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFKKESK

Specific function: Part of the ABC transporter complex wtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1176

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=184, Percent_Identity=24.4565217391304, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787369, Length=245, Percent_Identity=26.530612244898, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32717; Mature: 32717

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKMKPYILLLPVTIIIVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEILTSREFV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
ESLKFSLFTCILSSLIAEFIGVVLAYIIFTHKKRSKILDVIYKIPIIIPHTVAVLLIINM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYVWKEIPFIILVIYAVLTNIDE
HHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
KMWYLSRTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEECCCCCCCCCE
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFKKESK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEKMKPYILLLPVTIIIVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEILTSREFV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
ESLKFSLFTCILSSLIAEFIGVVLAYIIFTHKKRSKILDVIYKIPIIIPHTVAVLLIINM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYVWKEIPFIILVIYAVLTNIDE
HHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
KMWYLSRTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEECCCCCCCCCE
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFKKESK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]