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The map label for this gene is ydhD [H]

Identifier: 170757787

GI number: 170757787

Start: 1346662

End: 1348176

Strand: Direct

Name: ydhD [H]

Synonym: CLD_3356

Alternate gene names: 170757787

Gene position: 1346662-1348176 (Clockwise)

Preceding gene: 170756785

Following gene: 170755524

Centisome position: 34.02

GC content: 29.24

Gene sequence:

>1515_bases
ATGTGGAGACAACCTAATATAAGCTATATAGTTAAACCAGGAGATAGTTTATTTACTATTGCTAGATCATATGGTATAAC
TGTTGAACAATTAAAAGAATATAATGGACTTGTTTCTAACGACTTATATGTAGGACAACAAATTTTTATACCTATATCTA
TTTATAAAGTACAAAGAGGAGATAGTTTATATTATATTGCCAAAAAATTTGATACTACCGTAGAAAGTTTAATGGTATTA
AATAACTTGGATAGTATAAATTTAAATATAGGACAAATACTCTATATACCTCTTTATACTGAAGCTATAATGAAAGTAGA
GGACGGAAATATAAGGAGTCAACCTAGTATAAACTCAAAGATACTATACAAAATGGCTAAAGGTGCTAAGCTTCCAATTA
TAGGTGTATATAAGGATTTTTATAAAATAAAATTATTTAATGGAAATGAAGGCTTTGTATCAAAAGCTATAGTAGATTTT
AAAACTTATGGAAATATGAAACCTGTAGTAGCTGTAGATGGATTTTATACATTAGAAGAAGGAGAAACTTTGCCAAGTTC
TTACGAGTCTTTTGTTACTAATATAAATTTAATATCTGAAATATGTTTATTTATGTTTAGGATAGATCCGAGCGATGCTA
CGGCCATAGAAAAGTTTGGGGATTTTACAGATGAGTATGTAAAAGAACTTGTTAATATTGCTCATAGAAATAATGTTAGA
GTACTAGCTGTAGTTCATAATTTGCTTTATAGGCCTGGTGGAACTACAAAGGCTAAAGACTTAGTTAAATCATTAGTGTC
TACTAGAGAAAATAGACAAATTTTTATAAACAATTTAATAAGTCTTATAGAAAAGTACAATTTTGATGGAGTAAATATAG
ATATTGAAGATGTTTATATAGAAGATAAGGATAATTTATCTTCCCTATATTTAGAAATGGGAAGGGAATTTAGAAGAAAA
GGATATTTTTTATCAGCCTCTATACCATCAAGAGTTAGCGATGAACCCTTTAATCCTTTTTCAGATCCTTTTGATTATAG
AATTATAGGAAGTGCTGTAGATGAATTTATAGTTATGTTATATAACGAACATGGATGGCCAGGTAGTGGACCAGGACCAG
TGGTTTCAATAGGATGGATGAATAGAGTATTAAATTATACTATAACTAGAGTTCCAAGAAATAAAGTAGTAGCTGCAGTT
TCAGTGTTTGGATTTGATTTTAATTTAACCACAGGAAGAAACACTTATGTTACTTATGCAGGAGCCATAGAAATAGCTAA
AAGATATGGAAAAGATATAATATTCGATGAAGAAACAAAAACGCCTATGTTTAGTTATGTGGATGAAAATGGTAATAATC
ATGAAGTTTGGTTTGAAAATGCTGAGAGTATATACGCAAAGGCAGAATTAGCTTTCAATAAGGGTATAAAAGGAATAGCT
CTATGGAGATTAGGAATGGAAGACAATAAAATTTGGGATTCTATGAAAAAAGATATAGTAGTTAAAATGGCTTGA

Upstream 100 bases:

>100_bases
AAAAAAACATTATTTCTTTATAAAGAAAGTGTTAATTATATAATCAAAAAAATTATAGTATATATTATAAGAATGAAATC
AATATTAGAAAGGAATAAAT

Downstream 100 bases:

>100_bases
TGGTATAATTTAACTAGTAACCCAGTACATGGTGCTGGGTCCCTCATAATTTTATATAATTAAAGTAAAAAATAGTTATT
GGGGAAAATTCCTTAATTAT

Product: glycosy hydrolase family protein

Products: 1,6-Anhydrobond In The Muramic Acid Residue [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MWRQPNISYIVKPGDSLFTIARSYGITVEQLKEYNGLVSNDLYVGQQIFIPISIYKVQRGDSLYYIAKKFDTTVESLMVL
NNLDSINLNIGQILYIPLYTEAIMKVEDGNIRSQPSINSKILYKMAKGAKLPIIGVYKDFYKIKLFNGNEGFVSKAIVDF
KTYGNMKPVVAVDGFYTLEEGETLPSSYESFVTNINLISEICLFMFRIDPSDATAIEKFGDFTDEYVKELVNIAHRNNVR
VLAVVHNLLYRPGGTTKAKDLVKSLVSTRENRQIFINNLISLIEKYNFDGVNIDIEDVYIEDKDNLSSLYLEMGREFRRK
GYFLSASIPSRVSDEPFNPFSDPFDYRIIGSAVDEFIVMLYNEHGWPGSGPGPVVSIGWMNRVLNYTITRVPRNKVVAAV
SVFGFDFNLTTGRNTYVTYAGAIEIAKRYGKDIIFDEETKTPMFSYVDENGNNHEVWFENAESIYAKAELAFNKGIKGIA
LWRLGMEDNKIWDSMKKDIVVKMA

Sequences:

>Translated_504_residues
MWRQPNISYIVKPGDSLFTIARSYGITVEQLKEYNGLVSNDLYVGQQIFIPISIYKVQRGDSLYYIAKKFDTTVESLMVL
NNLDSINLNIGQILYIPLYTEAIMKVEDGNIRSQPSINSKILYKMAKGAKLPIIGVYKDFYKIKLFNGNEGFVSKAIVDF
KTYGNMKPVVAVDGFYTLEEGETLPSSYESFVTNINLISEICLFMFRIDPSDATAIEKFGDFTDEYVKELVNIAHRNNVR
VLAVVHNLLYRPGGTTKAKDLVKSLVSTRENRQIFINNLISLIEKYNFDGVNIDIEDVYIEDKDNLSSLYLEMGREFRRK
GYFLSASIPSRVSDEPFNPFSDPFDYRIIGSAVDEFIVMLYNEHGWPGSGPGPVVSIGWMNRVLNYTITRVPRNKVVAAV
SVFGFDFNLTTGRNTYVTYAGAIEIAKRYGKDIIFDEETKTPMFSYVDENGNNHEVWFENAESIYAKAELAFNKGIKGIA
LWRLGMEDNKIWDSMKKDIVVKMA
>Mature_504_residues
MWRQPNISYIVKPGDSLFTIARSYGITVEQLKEYNGLVSNDLYVGQQIFIPISIYKVQRGDSLYYIAKKFDTTVESLMVL
NNLDSINLNIGQILYIPLYTEAIMKVEDGNIRSQPSINSKILYKMAKGAKLPIIGVYKDFYKIKLFNGNEGFVSKAIVDF
KTYGNMKPVVAVDGFYTLEEGETLPSSYESFVTNINLISEICLFMFRIDPSDATAIEKFGDFTDEYVKELVNIAHRNNVR
VLAVVHNLLYRPGGTTKAKDLVKSLVSTRENRQIFINNLISLIEKYNFDGVNIDIEDVYIEDKDNLSSLYLEMGREFRRK
GYFLSASIPSRVSDEPFNPFSDPFDYRIIGSAVDEFIVMLYNEHGWPGSGPGPVVSIGWMNRVLNYTITRVPRNKVVAAV
SVFGFDFNLTTGRNTYVTYAGAIEIAKRYGKDIIFDEETKTPMFSYVDENGNNHEVWFENAESIYAKAELAFNKGIKGIA
LWRLGMEDNKIWDSMKKDIVVKMA

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG3858

COG function: function code R; Predicted glycosyl hydrolase

Gene ontology:

Cell location: Spore wall (Probable). Note=Probably localized either on the surface of the outer spore membrane and/or in the inner spore coat [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Homo sapiens, GI4758092, Length=348, Percent_Identity=22.9885057471264, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573679, Length=325, Percent_Identity=23.6923076923077, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011583
- InterPro:   IPR001223
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF00704 Glyco_hydro_18; PF01476 LysM [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 57373; Mature: 57373

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRQPNISYIVKPGDSLFTIARSYGITVEQLKEYNGLVSNDLYVGQQIFIPISIYKVQRG
CCCCCCCCEEECCCCCEEEEHHHCCCCHHHHHHHCCCCCCCEEECCEEEEEEEEEEEECC
DSLYYIAKKFDTTVESLMVLNNLDSINLNIGQILYIPLYTEAIMKVEDGNIRSQPSINSK
CEEEEEEEHHHHHHHHHHHHCCCCCCEECCCEEEEEEEEEEEHEEECCCCCCCCCCCCHH
ILYKMAKGAKLPIIGVYKDFYKIKLFNGNEGFVSKAIVDFKTYGNMKPVVAVDGFYTLEE
HHHHHHCCCCCCEEEEECCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCEEEECC
GETLPSSYESFVTNINLISEICLFMFRIDPSDATAIEKFGDFTDEYVKELVNIAHRNNVR
CCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCE
VLAVVHNLLYRPGGTTKAKDLVKSLVSTRENRQIFINNLISLIEKYNFDGVNIDIEDVYI
EEEEHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEEEEE
EDKDNLSSLYLEMGREFRRKGYFLSASIPSRVSDEPFNPFSDPFDYRIIGSAVDEFIVML
ECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHEEE
YNEHGWPGSGPGPVVSIGWMNRVLNYTITRVPRNKVVAAVSVFGFDFNLTTGRNTYVTYA
ECCCCCCCCCCCCEEEHHHHHHHHHHEEEECCCCCEEEEEEEEEEEEEEECCCCEEEEEE
GAIEIAKRYGKDIIFDEETKTPMFSYVDENGNNHEVWFENAESIYAKAELAFNKGIKGIA
HHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCEEEEECCCHHEEEEEHHHHCCCCEEE
LWRLGMEDNKIWDSMKKDIVVKMA
EEEECCCCCHHHHHHHHCEEEEEC
>Mature Secondary Structure
MWRQPNISYIVKPGDSLFTIARSYGITVEQLKEYNGLVSNDLYVGQQIFIPISIYKVQRG
CCCCCCCCEEECCCCCEEEEHHHCCCCHHHHHHHCCCCCCCEEECCEEEEEEEEEEEECC
DSLYYIAKKFDTTVESLMVLNNLDSINLNIGQILYIPLYTEAIMKVEDGNIRSQPSINSK
CEEEEEEEHHHHHHHHHHHHCCCCCCEECCCEEEEEEEEEEEHEEECCCCCCCCCCCCHH
ILYKMAKGAKLPIIGVYKDFYKIKLFNGNEGFVSKAIVDFKTYGNMKPVVAVDGFYTLEE
HHHHHHCCCCCCEEEEECCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCEEEECC
GETLPSSYESFVTNINLISEICLFMFRIDPSDATAIEKFGDFTDEYVKELVNIAHRNNVR
CCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCE
VLAVVHNLLYRPGGTTKAKDLVKSLVSTRENRQIFINNLISLIEKYNFDGVNIDIEDVYI
EEEEHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEEEEE
EDKDNLSSLYLEMGREFRRKGYFLSASIPSRVSDEPFNPFSDPFDYRIIGSAVDEFIVML
ECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHEEE
YNEHGWPGSGPGPVVSIGWMNRVLNYTITRVPRNKVVAAVSVFGFDFNLTTGRNTYVTYA
ECCCCCCCCCCCCEEEHHHHHHHHHHEEEECCCCCEEEEEEEEEEEEEEECCCCEEEEEE
GAIEIAKRYGKDIIFDEETKTPMFSYVDENGNNHEVWFENAESIYAKAELAFNKGIKGIA
HHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCEEEEECCCHHEEEEEHHHHCCCCEEE
LWRLGMEDNKIWDSMKKDIVVKMA
EEEECCCCCHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 12177332 [H]