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The map label for this gene is xerC [H]

Identifier: 170757708

GI number: 170757708

Start: 2700571

End: 2701566

Strand: Reverse

Name: xerC [H]

Synonym: CLD_2047

Alternate gene names: 170757708

Gene position: 2701566-2700571 (Counterclockwise)

Preceding gene: 170756871

Following gene: 170754767

Centisome position: 68.25

GC content: 30.32

Gene sequence:

>996_bases
ATGTGTAATACAAATAGCAAGGATGAAGTTGTAATTAAATTAGTTGGGAAATTATCTTTGGAGTTTCCAGAAATAGATCA
ACTAAAAGTTAGAGAAATAGTTGAGGAAGTTCTTTATAAATATAATATATTGCCACAAGAAAAAGCATTAATGACAAGTG
ATGTAGAAGAAAAATTACAAATATACTTAGCATCTAAGAAATTGGATGGATTGAGTTTAGAAACATTAAAAAACTATCAA
TATAATTTAGCTATATTTGCAGATTATTTAAGAAAACCACTAGCAACTATAAATACAATGGATCTAAGAATGTTCTTAGG
GGCTAGATGTAAGAATATGAAGCCAAGTAGTATGAACGGACAAATATCAATTTTAAAAAGTTTCTTTGGTTGGCTTGAAG
CTGAAGAGTATATACCCAAAAATCCTGCAGCTAAACTAAAGCAAACTAAAGAGCCTAAAAGAGTTAGGAAGCCATTAACA
GAGGAAGAGGCTGAATTATTAAGACAAGCTTGCGAAACAGACAGACAAAAGGCATTGACAGAGTTCTTAATATCTACAGG
ATGCAGACTGGATGAAGTTTTTAAAGTAAATAAAGACAATATTAATTGGCATGAAATGAGCCTATTTGTAGTTGGTAAAG
GAGATAAGGAACGAAAAGTTTATTTCAATACAAAAGCCAAAATTTTATTAAAAAAATATTTATTTTCAAGGGAAGATGAT
GATCCTGCATTATTTGTTACATCCAAAAGACCTTATCATAGATTAGGAAAAAGGAGTATTCAAAGAGAATTTAAAAAGAT
AGCGAATATGGCAGGAATAGAAAAGTCAATACATCCTCACTTATTTAGACACTCTTTTGCAACATATAAAATTAATAGTG
GTATGCCAATGCCAATTATACAACACTTAATGGGCCACGAGAGCCCAGCGACTACTCAAATTTATGCGCAACTATCAGAA
GAAACTGTAAAATATGAATATAAAAAAATATCTTAA

Upstream 100 bases:

>100_bases
GAGCTAGTTAGTTTGGACAACCGGTTAGCTCTCTTAAAAATAAACTACTAGAGATATTGTAACATTATTGTATCTCGGTG
GCAATATAGGAGGAAAAATT

Downstream 100 bases:

>100_bases
GGAGTGTAACTATGATTAAAATGAGAGGAAAAACAAAAATACTTGTATTGCCGTACAGGAATTTCAAACATAGAATTAGA
CTTACAAAAAGATATGAAAA

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MCNTNSKDEVVIKLVGKLSLEFPEIDQLKVREIVEEVLYKYNILPQEKALMTSDVEEKLQIYLASKKLDGLSLETLKNYQ
YNLAIFADYLRKPLATINTMDLRMFLGARCKNMKPSSMNGQISILKSFFGWLEAEEYIPKNPAAKLKQTKEPKRVRKPLT
EEEAELLRQACETDRQKALTEFLISTGCRLDEVFKVNKDNINWHEMSLFVVGKGDKERKVYFNTKAKILLKKYLFSREDD
DPALFVTSKRPYHRLGKRSIQREFKKIANMAGIEKSIHPHLFRHSFATYKINSGMPMPIIQHLMGHESPATTQIYAQLSE
ETVKYEYKKIS

Sequences:

>Translated_331_residues
MCNTNSKDEVVIKLVGKLSLEFPEIDQLKVREIVEEVLYKYNILPQEKALMTSDVEEKLQIYLASKKLDGLSLETLKNYQ
YNLAIFADYLRKPLATINTMDLRMFLGARCKNMKPSSMNGQISILKSFFGWLEAEEYIPKNPAAKLKQTKEPKRVRKPLT
EEEAELLRQACETDRQKALTEFLISTGCRLDEVFKVNKDNINWHEMSLFVVGKGDKERKVYFNTKAKILLKKYLFSREDD
DPALFVTSKRPYHRLGKRSIQREFKKIANMAGIEKSIHPHLFRHSFATYKINSGMPMPIIQHLMGHESPATTQIYAQLSE
ETVKYEYKKIS
>Mature_331_residues
MCNTNSKDEVVIKLVGKLSLEFPEIDQLKVREIVEEVLYKYNILPQEKALMTSDVEEKLQIYLASKKLDGLSLETLKNYQ
YNLAIFADYLRKPLATINTMDLRMFLGARCKNMKPSSMNGQISILKSFFGWLEAEEYIPKNPAAKLKQTKEPKRVRKPLT
EEEAELLRQACETDRQKALTEFLISTGCRLDEVFKVNKDNINWHEMSLFVVGKGDKERKVYFNTKAKILLKKYLFSREDD
DPALFVTSKRPYHRLGKRSIQREFKKIANMAGIEKSIHPHLFRHSFATYKINSGMPMPIIQHLMGHESPATTQIYAQLSE
ETVKYEYKKIS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=281, Percent_Identity=31.3167259786477, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=28.8659793814433, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38472; Mature: 38472

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNTNSKDEVVIKLVGKLSLEFPEIDQLKVREIVEEVLYKYNILPQEKALMTSDVEEKLQ
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IYLASKKLDGLSLETLKNYQYNLAIFADYLRKPLATINTMDLRMFLGARCKNMKPSSMNG
HHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QISILKSFFGWLEAEEYIPKNPAAKLKQTKEPKRVRKPLTEEEAELLRQACETDRQKALT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EFLISTGCRLDEVFKVNKDNINWHEMSLFVVGKGDKERKVYFNTKAKILLKKYLFSREDD
HHHHHCCCCHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCC
DPALFVTSKRPYHRLGKRSIQREFKKIANMAGIEKSIHPHLFRHSFATYKINSGMPMPII
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHCCEEEEECCCCCHHHH
QHLMGHESPATTQIYAQLSEETVKYEYKKIS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCNTNSKDEVVIKLVGKLSLEFPEIDQLKVREIVEEVLYKYNILPQEKALMTSDVEEKLQ
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IYLASKKLDGLSLETLKNYQYNLAIFADYLRKPLATINTMDLRMFLGARCKNMKPSSMNG
HHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QISILKSFFGWLEAEEYIPKNPAAKLKQTKEPKRVRKPLTEEEAELLRQACETDRQKALT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EFLISTGCRLDEVFKVNKDNINWHEMSLFVVGKGDKERKVYFNTKAKILLKKYLFSREDD
HHHHHCCCCHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCC
DPALFVTSKRPYHRLGKRSIQREFKKIANMAGIEKSIHPHLFRHSFATYKINSGMPMPII
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHCCEEEEECCCCCHHHH
QHLMGHESPATTQIYAQLSEETVKYEYKKIS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]