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The map label for this gene is resE [H]

Identifier: 170757632

GI number: 170757632

Start: 828859

End: 829896

Strand: Direct

Name: resE [H]

Synonym: CLD_0057

Alternate gene names: 170757632

Gene position: 828859-829896 (Clockwise)

Preceding gene: 170755464

Following gene: 170757092

Centisome position: 20.94

GC content: 34.97

Gene sequence:

>1038_bases
ATGAAAATATTGGTAAACAGGAAAATCAAAAAACTTTTTCGTTTGGTATTGCTGTTTATAGTAGCATTCACCTTGATTTC
TGCTGTTTTCATAGTTTTGAAATTTGAAACTGTAGCATTGTGTATATTGGTATGTTCTTTGTGCATGAGTATTTTGATAT
TGGCAATAGGTTATAGGTATTTCAAGGAACAAAATATAATCATGGAAAATGCGGTAATGCAAATCAAAGAATATATTTCT
GGAAATCAAAACGCACGTATTGAATGTGATGATGAAGGAGAGCTATACAGACTATTTCATGAAGTAAATTCCTTAGTTTC
TATTTTAAATGCCCACGCTGAAAATGAGGGAAAAGCAAAAAAATTTTTGAAAGATACCATTTCCGATATTTCCCACCAGT
TAAAAACTCCGCTTGCTGCCCTTAATATCTACAATGGAATTATGCAAGAAGAAGCAAAGAGTTTACCGACAATCAAAGAG
TTTACTGTTCTTTCAGAGCAGGAGCTTGACAGAATAGAAATACTGGTGCAAAATCTCTTGAAAATTACAAAACTCGATGC
CGGAACAATCGTGATTGAGAAAGCTGAAGAAAATGTATCTGAAATGATGGGTAGTATAGAAAGGCACTTTTCATTTCGTG
CCAAGCAGGAGGAAAAGGAAATATATCTGTCCGGCGATGATGACGTCACCTTATTATGTGACCGTAATTGGCTAATTGAA
GCAATCAGTAATATTGTTAAAAACGCTTTTGACCATACGCAAAAAGGAAATGCTATATATATTGAATGGAAACAATTTGC
GTCTGTTATTCAAGTCATCATAAAAGACAACGGAAGCGGTATTCACCCAGAGGATTTGCACCATATTTTCAAAAGATTTT
ATCGCAGTCGTTTTTCTAAAGACACGCAAGGTATCGGACTTGGGTTACCGCTTGTGAAAGCTATTGTTGAAGCACACAGC
GGAACAATCGAAGTTGACAGCGAATTGGGTATTGGCACTACTTTTACAATCAATTTTTTAATTCCTACAAAATTGTAG

Upstream 100 bases:

>100_bases
GACTGCGTACAAAAATCGAAGATAATCCGGGAGAGCCTCAAAAAATAGTGACTGTTCGGCGTATGGGGTATAAATGGAGT
ACTGTTGATTGGGGTGTACG

Downstream 100 bases:

>100_bases
GGTAAGTGTCATATAGTAGTAAGATTGACATGATAATCTTTCAATATCAAGACAGAAAGAGGTAGATAACCTATGAATTT
ATTGGAAGTTAGATCAATTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKILVNRKIKKLFRLVLLFIVAFTLISAVFIVLKFETVALCILVCSLCMSILILAIGYRYFKEQNIIMENAVMQIKEYIS
GNQNARIECDDEGELYRLFHEVNSLVSILNAHAENEGKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPTIKE
FTVLSEQELDRIEILVQNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEEKEIYLSGDDDVTLLCDRNWLIE
AISNIVKNAFDHTQKGNAIYIEWKQFASVIQVIIKDNGSGIHPEDLHHIFKRFYRSRFSKDTQGIGLGLPLVKAIVEAHS
GTIEVDSELGIGTTFTINFLIPTKL

Sequences:

>Translated_345_residues
MKILVNRKIKKLFRLVLLFIVAFTLISAVFIVLKFETVALCILVCSLCMSILILAIGYRYFKEQNIIMENAVMQIKEYIS
GNQNARIECDDEGELYRLFHEVNSLVSILNAHAENEGKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPTIKE
FTVLSEQELDRIEILVQNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEEKEIYLSGDDDVTLLCDRNWLIE
AISNIVKNAFDHTQKGNAIYIEWKQFASVIQVIIKDNGSGIHPEDLHHIFKRFYRSRFSKDTQGIGLGLPLVKAIVEAHS
GTIEVDSELGIGTTFTINFLIPTKL
>Mature_345_residues
MKILVNRKIKKLFRLVLLFIVAFTLISAVFIVLKFETVALCILVCSLCMSILILAIGYRYFKEQNIIMENAVMQIKEYIS
GNQNARIECDDEGELYRLFHEVNSLVSILNAHAENEGKAKKFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPTIKE
FTVLSEQELDRIEILVQNLLKITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEEKEIYLSGDDDVTLLCDRNWLIE
AISNIVKNAFDHTQKGNAIYIEWKQFASVIQVIIKDNGSGIHPEDLHHIFKRFYRSRFSKDTQGIGLGLPLVKAIVEAHS
GTIEVDSELGIGTTFTINFLIPTKL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=31.7991631799163, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786783, Length=214, Percent_Identity=30.3738317757009, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=26.6932270916335, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788279, Length=293, Percent_Identity=24.9146757679181, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=335, Percent_Identity=25.3731343283582, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=25.2173913043478, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=26.1467889908257, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=280, Percent_Identity=25, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=218, Percent_Identity=27.9816513761468, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786912, Length=220, Percent_Identity=26.3636363636364, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=23.6, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=24.7826086956522, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789403, Length=198, Percent_Identity=26.2626262626263, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39182; Mature: 39182

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVNRKIKKLFRLVLLFIVAFTLISAVFIVLKFETVALCILVCSLCMSILILAIGYRY
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKEQNIIMENAVMQIKEYISGNQNARIECDDEGELYRLFHEVNSLVSILNAHAENEGKAK
HHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
KFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPTIKEFTVLSEQELDRIEILVQNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHH
KITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEEKEIYLSGDDDVTLLCDRNWLIE
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCHHHH
AISNIVKNAFDHTQKGNAIYIEWKQFASVIQVIIKDNGSGIHPEDLHHIFKRFYRSRFSK
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
DTQGIGLGLPLVKAIVEAHSGTIEVDSELGIGTTFTINFLIPTKL
CCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MKILVNRKIKKLFRLVLLFIVAFTLISAVFIVLKFETVALCILVCSLCMSILILAIGYRY
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKEQNIIMENAVMQIKEYISGNQNARIECDDEGELYRLFHEVNSLVSILNAHAENEGKAK
HHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
KFLKDTISDISHQLKTPLAALNIYNGIMQEEAKSLPTIKEFTVLSEQELDRIEILVQNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHH
KITKLDAGTIVIEKAEENVSEMMGSIERHFSFRAKQEEKEIYLSGDDDVTLLCDRNWLIE
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCHHHH
AISNIVKNAFDHTQKGNAIYIEWKQFASVIQVIIKDNGSGIHPEDLHHIFKRFYRSRFSK
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
DTQGIGLGLPLVKAIVEAHSGTIEVDSELGIGTTFTINFLIPTKL
CCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]