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The map label for this gene is lspA

Identifier: 170757577

GI number: 170757577

Start: 1638728

End: 1639171

Strand: Direct

Name: lspA

Synonym: CLD_3075

Alternate gene names: 170757577

Gene position: 1638728-1639171 (Clockwise)

Preceding gene: 170756818

Following gene: 170756442

Centisome position: 41.4

GC content: 23.87

Gene sequence:

>444_bases
TTGGGAATAATTGTATTGATATTGGGTATATTTTTAGATAGAATAAGTAAAATATGGGCTTTAAATACATTAGCTTCTGG
TAAAGATATAGTTGTAATAAAAAATTTATTTACCTTTTCTTATTTAGAAAATAGGGGAGCAGCTTTTGGAATATTTCAAA
ATAGATTAATATTTCTGAGTTTAATAACTGCAATTGTAATTTTAGGAGTAGTATATTTTATTGTAAAGTACAAGCCGACT
TCAAAATTACTAAAAATATCTTTATCATTAATAATAAGTGGTGCTATAGGTAATTTAATAGATAGGATTTATTATAAATT
TGTAGTAGATTTTATTATGTTACACTATAAAGATGTTTATTATTTCCCTACATTTAATGTAGCGGATATGTTAGTAGTTA
TAGGTACTGTATTACTAGCTATATACATATTAAAGGAAGAGTAG

Upstream 100 bases:

>100_bases
TAAATATAATTTATATATATTATTAATTTAAAAGTCAATAGTATTTATAAAAATTCTATTTAATAACAAGATGTGACTTT
ATAGCAATAGGGGGGATACT

Downstream 100 bases:

>100_bases
TTTATGGAAAAAATAAGTTTACAAGTAGAAAAAGAATTTGATAATGTAAGATTAGATTTATACTTATCAAAAATATTTGA
AGACAAATCTAGATCTTATC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MGIIVLILGIFLDRISKIWALNTLASGKDIVVIKNLFTFSYLENRGAAFGIFQNRLIFLSLITAIVILGVVYFIVKYKPT
SKLLKISLSLIISGAIGNLIDRIYYKFVVDFIMLHYKDVYYFPTFNVADMLVVIGTVLLAIYILKEE

Sequences:

>Translated_147_residues
MGIIVLILGIFLDRISKIWALNTLASGKDIVVIKNLFTFSYLENRGAAFGIFQNRLIFLSLITAIVILGVVYFIVKYKPT
SKLLKISLSLIISGAIGNLIDRIYYKFVVDFIMLHYKDVYYFPTFNVADMLVVIGTVLLAIYILKEE
>Mature_146_residues
GIIVLILGIFLDRISKIWALNTLASGKDIVVIKNLFTFSYLENRGAAFGIFQNRLIFLSLITAIVILGVVYFIVKYKPTS
KLLKISLSLIISGAIGNLIDRIYYKFVVDFIMLHYKDVYYFPTFNVADMLVVIGTVLLAIYILKEE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=134, Percent_Identity=36.5671641791045, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 16680; Mature: 16548

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIIVLILGIFLDRISKIWALNTLASGKDIVVIKNLFTFSYLENRGAAFGIFQNRLIFLS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEHHHHHHHHHHH
LITAIVILGVVYFIVKYKPTSKLLKISLSLIISGAIGNLIDRIYYKFVVDFIMLHYKDVY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YFPTFNVADMLVVIGTVLLAIYILKEE
EECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GIIVLILGIFLDRISKIWALNTLASGKDIVVIKNLFTFSYLENRGAAFGIFQNRLIFLS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEHHHHHHHHHHH
LITAIVILGVVYFIVKYKPTSKLLKISLSLIISGAIGNLIDRIYYKFVVDFIMLHYKDVY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YFPTFNVADMLVVIGTVLLAIYILKEE
EECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA