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The map label for this gene is selA

Identifier: 170757431

GI number: 170757431

Start: 3228376

End: 3229764

Strand: Reverse

Name: selA

Synonym: CLD_1568

Alternate gene names: 170757431

Gene position: 3229764-3228376 (Counterclockwise)

Preceding gene: 170754564

Following gene: 170757801

Centisome position: 81.6

GC content: 30.02

Gene sequence:

>1389_bases
ATGGATAAAAAACAATTATTACGTAATTTACCTAAAATAGATGAGCTGTTGAAGGAAGAAATTGTTAATAGATATCTACA
AGAAAATTCTAGAACCTTAGTAGTAGATAGTCTTAGGCAATCTATAGATCACTATAGAGGCGAGATTTTAAAAAATAATA
TAGATAGTTTTACTAAGGAAAATGTTGTAAATTATTTCATAGATACTTTAGAAGAAAATAAAAGTACTAAATTTAAAAAA
GTTATTAATGCTACAGGTGTGGTAATACATACGAATTTAGGAAGATCCTTATTAGCTAAAGAGGCGATAGAAAATGTGAT
AAAGGTATCTGAAAACTATAGCAATCTAGAATATGACTTAAAAGATGGGAAAAGAGGATCAAGATATAGTCATGTAGAGG
AATTGATTAAGAAAGTTACAGGGGCTGAAGCTGCTATGGTAGTTAATAACAATGCAGCAGCAGTTATGTTAGCTCTAAAT
ACTCTTTGTGAGGGAAGAGAAGCTATAGTATCAAGAGGTCAGCTAGTAGAGATAGGCGGATCTTTCAGGATACCAGATGT
AATGAAGTTTAGTAGAGCTCATTTAGTTGAAGTAGGTACTACAAATAGAACACATTTATATGATTATGAAAATAATATAA
ATGAAAATACAGGAGTTTTACTTAAAGTCCATACTTCAAATTTTAAAATAATGGGTTTTACAGAAGAGGTATCTTCAGAA
GAAATGGTACAATTAGGTGGAAAATATAAATTACCTGTAATGGAGGACATAGGTAGTGGTACTTTGGTTGACTTTTCTAA
GTATGGCTTTACTTATGAACCAACTGTTCAAAGTAGCCTTGAAAAGGGGGTAGATGTGGTAACATTTAGTGGAGATAAAA
TGTTAGGAGGACCACAAGCAGGAATAATAGTAGGTAAAAAGAAATACATAGATAAAATGAAAAAGAATCAATTAACTAGA
GCCTTAAGAATAGATAAAATGACTTTGGCGGCTTTAGAAGGAACTTTAAAATGCTATATAGACGAAAAGGAAGCTATAGA
AAATATTCCAACATTAAACATGATTTTAAGTTCCAAAGATATCCATAAAAAAAGAGCCCAAAGATTGAAAAGAAGACTTC
AAAATAATGTTAAAGACTTTAATTTTAAAGTATCAGAGGATCTTTCTATGGTAGGCGGAGGCTCTATGCCAGGGGAGAGA
ATACCTACCTATGTGGTAAAAGTGAATAGTGATAAAATAACAGCAGAAAAGATAGAAGAAAAATTAAGATTAAGTAAAAA
TCCTATAATAGTTAGAGTAAGCAAAGATGAAGTAATATTAGACGTGAGAACTTTATTTGAGAGAGATTTTAATATAATAG
TAGAAGAATTTAAAAAATTATTAAAATAA

Upstream 100 bases:

>100_bases
AAGGAAACAAGATAAATATATAATAGTTGAATAAAATATTATACTATTTATGACAATAAGTATTGAATATACAACATAAT
TAAGGAATGGAGAATAGGGC

Downstream 100 bases:

>100_bases
TTGAGAATGGTGATGTTTATGAAGAACGTAATAATAGGAACAGCTGGACATATAGATCATGGTAAAACCACTTTAATAAA
AGCATTAACAGGAAGAGAAA

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDHYRGEILKNNIDSFTKENVVNYFIDTLEENKSTKFKK
VINATGVVIHTNLGRSLLAKEAIENVIKVSENYSNLEYDLKDGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALN
TLCEGREAIVSRGQLVEIGGSFRIPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQAGIIVGKKKYIDKMKKNQLTR
ALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKDIHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGER
IPTYVVKVNSDKITAEKIEEKLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK

Sequences:

>Translated_462_residues
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDHYRGEILKNNIDSFTKENVVNYFIDTLEENKSTKFKK
VINATGVVIHTNLGRSLLAKEAIENVIKVSENYSNLEYDLKDGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALN
TLCEGREAIVSRGQLVEIGGSFRIPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQAGIIVGKKKYIDKMKKNQLTR
ALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKDIHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGER
IPTYVVKVNSDKITAEKIEEKLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK
>Mature_462_residues
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDHYRGEILKNNIDSFTKENVVNYFIDTLEENKSTKFKK
VINATGVVIHTNLGRSLLAKEAIENVIKVSENYSNLEYDLKDGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALN
TLCEGREAIVSRGQLVEIGGSFRIPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQAGIIVGKKKYIDKMKKNQLTR
ALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKDIHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGER
IPTYVVKVNSDKITAEKIEEKLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=448, Percent_Identity=43.3035714285714, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 52307; Mature: 52307

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDHYRGEILKNNIDSFTKE
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVNYFIDTLEENKSTKFKKVINATGVVIHTNLGRSLLAKEAIENVIKVSENYSNLEYDL
HHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEC
KDGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALNTLCEGREAIVSRGQLVEIGG
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHCCHHHHHCCCCEEEECC
SFRIPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
CCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEHHHHCHH
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQA
HHHHCCCCCCCCHHHHCCCCCEEEHHHCCCEECCHHHHHHHCCCEEEEECCCCCCCCCCC
GIIVGKKKYIDKMKKNQLTRALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKD
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCHHHHHCCCH
IHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGERIPTYVVKVNSDKITAEKIEE
HHHHHHHHHHHHHHCCHHHCCEEECCCHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
KLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK
HHHCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDHYRGEILKNNIDSFTKE
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVNYFIDTLEENKSTKFKKVINATGVVIHTNLGRSLLAKEAIENVIKVSENYSNLEYDL
HHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEC
KDGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALNTLCEGREAIVSRGQLVEIGG
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHCCHHHHHCCCCEEEECC
SFRIPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
CCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEHHHHCHH
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQA
HHHHCCCCCCCCHHHHCCCCCEEEHHHCCCEECCHHHHHHHCCCEEEEECCCCCCCCCCC
GIIVGKKKYIDKMKKNQLTRALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKD
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCHHHHHCCCH
IHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGERIPTYVVKVNSDKITAEKIEE
HHHHHHHHHHHHHHCCHHHCCEEECCCHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
KLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK
HHHCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA