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The map label for this gene is lepB

Identifier: 170757120

GI number: 170757120

Start: 696553

End: 697161

Strand: Direct

Name: lepB

Synonym: CLD_0178

Alternate gene names: 170757120

Gene position: 696553-697161 (Clockwise)

Preceding gene: 170756149

Following gene: 170754978

Centisome position: 17.6

GC content: 28.08

Gene sequence:

>609_bases
ATGGATAAGAGAAAAGTTAAAAAAGAGATTGAAAGTTGGATTTTTTCTATTTTGGGGGCTATTCTTATTGCAGGTTTAGT
TAATAGTAAGGTTTTTGCAAAGGTCCGAGTACAACAAAGCTCTATGGAGAATACTTTACTTACTAATGAACAATTAGTAG
TAGATAAATTAAGCTATAACTTTGTAGAACCTAAAAAAGGAGATATAATTATTTTTCATGAAAATAAAGAAAAGGGAACT
ATAGCTGAGGATACTTTAGAAATGGTAGATAATATAATATCCATATTTAATAATAACAATAATTATATAGAAAAAGATGA
TAGATTAATTAAAAGAGTAATTGGTATTCCAGGGGATGAAATTGATATTAAAGATGGACATTTATATTTAAATGGTAAAA
GACTTGAAGAACCCTATGTAAAAGGGGAAACTATTGAAAGAGAATTTAAACTTCCTATTCAGGTTCCAGAAAACAAATTG
TTTGTTTTAGGTGATAACAGAATGATAAGTAAGGATAGTAGGATGTTTGGGCTTATTGATTATAAGCAAGTTGAAGGTAA
GGCAATATACAGGGTATATCCTTTCGATCACATAGGAAATATAAAGTAA

Upstream 100 bases:

>100_bases
ATTAGCTATTTTTATTATGATAAGAGAAATTAATTAATGTTTAAATTAATTACTATCATAGCATTGTGATTTAATTTTTG
AATTAGAGGGGGAAAATATT

Downstream 100 bases:

>100_bases
AATTGATTATAAATATTGTGTTTAGGTAACGCAATTTTATTATTATAATAATTTGAAAACTAAATTAAAATTATAAAAAA
TTAAAGTGGTATTTATTTTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase IB; Leader peptidase IB [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDEIDIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQVPENKL
FVLGDNRMISKDSRMFGLIDYKQVEGKAIYRVYPFDHIGNIK

Sequences:

>Translated_202_residues
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDEIDIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQVPENKL
FVLGDNRMISKDSRMFGLIDYKQVEGKAIYRVYPFDHIGNIK
>Mature_202_residues
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDEIDIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQVPENKL
FVLGDNRMISKDSRMFGLIDYKQVEGKAIYRVYPFDHIGNIK

Specific function: Essential for cell viability [H]

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23347; Mature: 23347

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCHHHCCCCEEEEEECCCC
FVEPKKGDIIIFHENKEKGTIAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDE
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCCE
IDIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQVPENKLFVLGDNRMISKDSRMFGLID
EEEECCEEEECCCCCCCCCCCCCCCCEEEECCEECCCCEEEEEECCEEECCCCCEEEEEE
YKQVEGKAIYRVYPFDHIGNIK
EEECCCEEEEEEECCHHCCCCC
>Mature Secondary Structure
MDKRKVKKEIESWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCHHHCCCCEEEEEECCCC
FVEPKKGDIIIFHENKEKGTIAEDTLEMVDNIISIFNNNNNYIEKDDRLIKRVIGIPGDE
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCCE
IDIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQVPENKLFVLGDNRMISKDSRMFGLID
EEEECCEEEECCCCCCCCCCCCCCCCEEEECCEECCCCEEEEEECCEEECCCCCEEEEEE
YKQVEGKAIYRVYPFDHIGNIK
EEECCCEEEEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA