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The map label for this gene is yeiT [H]

Identifier: 170757075

GI number: 170757075

Start: 3007698

End: 3009014

Strand: Reverse

Name: yeiT [H]

Synonym: CLD_1755

Alternate gene names: 170757075

Gene position: 3009014-3007698 (Counterclockwise)

Preceding gene: 170756273

Following gene: 170754614

Centisome position: 76.02

GC content: 33.03

Gene sequence:

>1317_bases
TTGGAAAATAAATTAACTTATATGAAAGAAAGAGAAGAAGTTTTTACACCTCTTCTAGCTATTGAAGAAGCATCAAGATG
TTTGCTATGTCATGATGCACCCTGTACAAAGGCGTGTCCAGCAGGTACAAATCCCGGAAAATTCATACGTTCATTACGTT
TTAGAAATTTTAATGGGGCCGTAGCTACAATTCGTGAAAATAATATATTAGGAGGAGTCTGTGCAAGAGTCTGTCCTACA
GATAAATATTGTGAAGGAGCCTGTAGTAGATGTGGTATAGATAAGCCTATTCAAATAGGGAGACTTCAACGCTATTTAGC
AGATTATGAACAATCAATAGGAATAAAAATTTTAGAAGCTGTACAAGCTACAAAAGAAAAAGTAGCTATTATAGGTTCAG
GTCCAAGTGGACTTGCAGCGGCAGCTCAATTAGCTTTAGAAGGCTATAAAGTAACTGTATTTGAAGCTAAAAATCAATTA
GGTGGATGGTTAACTTATGGAATACCAGAAGATAGGCTTCCACAAAAAGTTGTTGAAAATGAAATTGGATACATAAAGAA
TTTAGGTGTCCATTTTAGAACTAACTGTAAAGTTGGAAGAGATGTTAGTATAGATGATCTTAGAGAAGAAGGGTTTAAAG
CATTTTTAATAGCAGTAGGCATGCAAAAGAGTAAAGATATGGAAGTAAAAGGTAATAATTTAGAAGGAGTTGTTGCTGGA
ACAAATTTTTTAGCAGAAGCTAAAATTTCTAAGGGAAAAGTTAAAGTTGGCAGCAAAGTTATAGTTATAGGTGGAGGAGA
TGTTGCTATGGATTGTGCTGTAACTGCTAAATTATTAGGATCAGAAGATGTTAAGATAGTTTATAGAAGAACTATAGAAA
GAATGCCAGCAGATAGAAAGGAAATAGCTTATACCCAAGATTTAAATATACCAATATTTACAGGATTAAAGCCAGCTGAA
ATAATTGGACAAGCTGGAAAAGTGGATAGATTTAAAGCTACAGGAATGTTTGATGATTCAGAATTAAATCTTCCAGCAGA
TATGATTATATTTGCTATTGGACAAGAAGCAGAAGAAATAAAAGAATTAAAAGAAGCAGTAAAAGAAGTAGCTGCAACAA
AGGAAGTAACAATAGTAGAATTTAATGAAAAAGGAACAATTAAAACCCTAGATTATGCTACTAATATAGATGGGATTTTT
GCTTCAGGAGATATAATTGAAGGAGATAAAACTGTTGTAAATGCTGTAAAAGAAGGAAAAGAAGCAGCAAAGGCCATAGC
AAAATATTTATTAGCTAAGAAAGAAGGTGTAAGATAA

Upstream 100 bases:

>100_bases
AATAGACCATTTCTAAGTTAGAAATGGTCTATTTTTTTTGTTAAACTATTGTTATAACTGCAATTAACCTTTAAATATTA
AATATAAAGGAGGAATAATA

Downstream 100 bases:

>100_bases
TGAAAAGAAGAGATCTTTCCATAGAATTTTGTGGAGTAAAGTGTGAAAATCCATTTTTCTTATCATCATCACCAGTAGGA
AACTGTTACGAAATGTGTGC

Product: pyridine nucleotide-disulphide oxidoreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGAVATIRENNILGGVCARVCPT
DKYCEGACSRCGIDKPIQIGRLQRYLADYEQSIGIKILEAVQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEAKNQL
GGWLTYGIPEDRLPQKVVENEIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLIAVGMQKSKDMEVKGNNLEGVVAG
TNFLAEAKISKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRKEIAYTQDLNIPIFTGLKPAE
IIGQAGKVDRFKATGMFDDSELNLPADMIIFAIGQEAEEIKELKEAVKEVAATKEVTIVEFNEKGTIKTLDYATNIDGIF
ASGDIIEGDKTVVNAVKEGKEAAKAIAKYLLAKKEGVR

Sequences:

>Translated_438_residues
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGAVATIRENNILGGVCARVCPT
DKYCEGACSRCGIDKPIQIGRLQRYLADYEQSIGIKILEAVQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEAKNQL
GGWLTYGIPEDRLPQKVVENEIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLIAVGMQKSKDMEVKGNNLEGVVAG
TNFLAEAKISKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRKEIAYTQDLNIPIFTGLKPAE
IIGQAGKVDRFKATGMFDDSELNLPADMIIFAIGQEAEEIKELKEAVKEVAATKEVTIVEFNEKGTIKTLDYATNIDGIF
ASGDIIEGDKTVVNAVKEGKEAAKAIAKYLLAKKEGVR
>Mature_438_residues
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGAVATIRENNILGGVCARVCPT
DKYCEGACSRCGIDKPIQIGRLQRYLADYEQSIGIKILEAVQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEAKNQL
GGWLTYGIPEDRLPQKVVENEIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLIAVGMQKSKDMEVKGNNLEGVVAG
TNFLAEAKISKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRKEIAYTQDLNIPIFTGLKPAE
IIGQAGKVDRFKATGMFDDSELNLPADMIIFAIGQEAEEIKELKEAVKEVAATKEVTIVEFNEKGTIKTLDYATNIDGIF
ASGDIIEGDKTVVNAVKEGKEAAKAIAKYLLAKKEGVR

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli glutamate synthase [NADPH] small chain (GltD) and to E.coli AegA [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=449, Percent_Identity=30.7349665924276, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI237757300, Length=87, Percent_Identity=43.6781609195402, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1788468, Length=424, Percent_Identity=45.2830188679245, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1788811, Length=454, Percent_Identity=31.7180616740088, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789606, Length=445, Percent_Identity=31.0112359550562, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI87082180, Length=442, Percent_Identity=29.8642533936652, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1789243, Length=442, Percent_Identity=29.4117647058824, Blast_Score=137, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71984108, Length=445, Percent_Identity=29.6629213483146, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17570289, Length=465, Percent_Identity=28.6021505376344, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17543860, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320030, Length=480, Percent_Identity=29.1666666666667, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24640763, Length=437, Percent_Identity=30.8924485125858, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI18858217, Length=437, Percent_Identity=30.8924485125858, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28574881, Length=466, Percent_Identity=29.6137339055794, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24665539, Length=466, Percent_Identity=29.6137339055794, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24665547, Length=466, Percent_Identity=29.6137339055794, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24665543, Length=466, Percent_Identity=29.6137339055794, Blast_Score=158, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 47610; Mature: 47610

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGA
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC
VATIRENNILGGVCARVCPTDKYCEGACSRCGIDKPIQIGRLQRYLADYEQSIGIKILEA
EEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEAKNQLGGWLTYGIPEDRLPQKVVEN
HHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHH
EIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLIAVGMQKSKDMEVKGNNLEGVVAG
HHHHHHHCCEEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCEECCCCCCEEEEC
TNFLAEAKISKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRK
CCEEEECCCCCCEEEECCEEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EIAYTQDLNIPIFTGLKPAEIIGQAGKVDRFKATGMFDDSELNLPADMIIFAIGQEAEEI
HCEEEECCCCEEECCCCHHHHHCCCCCCCCEEECCCCCCCCCCCCHHHEEEEECCCHHHH
KELKEAVKEVAATKEVTIVEFNEKGTIKTLDYATNIDGIFASGDIIEGDKTVVNAVKEGK
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEECCCEECCCHHHHHHHHHHH
EAAKAIAKYLLAKKEGVR
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MENKLTYMKEREEVFTPLLAIEEASRCLLCHDAPCTKACPAGTNPGKFIRSLRFRNFNGA
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC
VATIRENNILGGVCARVCPTDKYCEGACSRCGIDKPIQIGRLQRYLADYEQSIGIKILEA
EEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEAKNQLGGWLTYGIPEDRLPQKVVEN
HHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHH
EIGYIKNLGVHFRTNCKVGRDVSIDDLREEGFKAFLIAVGMQKSKDMEVKGNNLEGVVAG
HHHHHHHCCEEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCEECCCCCCEEEEC
TNFLAEAKISKGKVKVGSKVIVIGGGDVAMDCAVTAKLLGSEDVKIVYRRTIERMPADRK
CCEEEECCCCCCEEEECCEEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EIAYTQDLNIPIFTGLKPAEIIGQAGKVDRFKATGMFDDSELNLPADMIIFAIGQEAEEI
HCEEEECCCCEEECCCCHHHHHCCCCCCCCEEECCCCCCCCCCCCHHHEEEEECCCHHHH
KELKEAVKEVAATKEVTIVEFNEKGTIKTLDYATNIDGIFASGDIIEGDKTVVNAVKEGK
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEECCCEECCCHHHHHHHHHHH
EAAKAIAKYLLAKKEGVR
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]