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The map label for this gene is stc [H]

Identifier: 170757048

GI number: 170757048

Start: 2097167

End: 2099257

Strand: Reverse

Name: stc [H]

Synonym: CLD_2665

Alternate gene names: 170757048

Gene position: 2099257-2097167 (Counterclockwise)

Preceding gene: 170757456

Following gene: 170754717

Centisome position: 53.04

GC content: 43.85

Gene sequence:

>2091_bases
ATGAGAAAATTATGGAGGAATCATGAAGGAATCATGAAAAAAACGATGTCTGTAGTGGCTTTGGATGCCAGAGCCGGAGA
GTTTTATGCAAAAGAAATCAATGAACTGTTTGGGGAATATGTGGAGATAGCATCCTACAATGTGAGTGACGGGTCTGCCG
TGGGAACGTTGCCAAAGGCAGATTTATTTGTGATTTCAACAGATGCATATGGTTCCGCAGAAGAGGTGGCCCGTCATGTT
CCTATAGACAGCCTTACCATGGGAATTGAAGTTTCCTACCGGTGGAGTACGTTGCAAAACCTTAGTATGATACCAAAGGG
AACCCGAGCTCTTTTTGTAAATATGACAGATACCATGGCTCGAGAGGCTATTGCACAGCTGCAACAGCTGGGGGTAAACC
ATATTCGTTTTATTCCATTTTACCCAGGTGCTGTTTTGGAAGAGCCGGTGGATATGGCTGTAACGCCGGAGGAGGAGAGA
TATGTACCTCAGAGCGTAAAGAAAGTTTTAAATATCGGACACCGTTCCTGTACCTCGGGAATGATGATTGAGATTGCCTT
GCGTATGGGACTTGAACAGTTGTTAGAGACGAAAAAATTCCAAAATTATTTCCAGGCGATGGCAACGAATAATTATAGTT
TTAATCAGATATATGCCCGCTCTAGAAGACTGGAAAGCCAATTCCATATTTTAATGGAAATATTGGATGAGGGACTGGTA
GGCGTTAATGAAAAGGGGGAGATTTTTGCATGCAATAAAAAAGCCTGCCAGATTGCAAAAATTGCGGAAAATCTTGTTAT
TGGCAGGTGCGGGGAAAAAGTATTTCCCTATATTCCCTTTTACAGTGCATTGAAGGATAAGAAAGAAATTTCGCCTAAAG
TGATTAAGCTAGGCGGCGTAAACGTAAGTATTGAAGTTATACCGGTTCTGCGGCAGAAGAAATGCATTGGTGCATTTGCT
ACTCTGCAGGAATTTAGTGAGCTGGAGTCCAAACAGAATGAGTTAAGAAGCCAGCTGCTGAAAAAGGGCTATTGTGCCAA
GTACACCTTTAATGATGTAATCGGAGAATCAGATTGTATCTGCCAGACAAAGGGGATTTTAAAGAGGATGGCGGCTACCG
AAAGTCCAGTTTTAATTGTAGGTGAAACAGGAACGGGAAAAGAACTGCTGGCTCATGCGGTGCATTGTGCATCTAAGCGG
AGCAAAGGTCCTTTTATTGCCATTAATGTGGCAGCTATGCCGGAAAATCTTCTGGAAAGCGAGCTTTTTGGATATGAAGA
GGGTGCATTTACCGGCGCAAAAAAAGGCGGACGCCCTGGGCTGTTTGAATTCGCCCATGGTGGTACATTATTCCTCGATG
AAGTAGAAGGTATGAGCCAGGCCATGCAGGTAAAGCTTCTGAGAGTTCTGCAAGAAGGCGAAGTCATGCGCGTAGGTGGT
AGCAGAATTGTAAGCGTTGATGTCAGAATTGTTGCAGCAACCAATGAATCTTTGGATCAGAAGGTGGAAGAAGGAGGTTT
CCGAAAGGATCTGTATTATCGTCTGAATACCTTGACGGTTGTAGTACCGCTGTTACGGGAACGGGGAGAGGATGTCTTTC
TTTTGATGGAGCATTTTAAAGAGGAGCTCCAGGGTGACTTTAAGTTATCGGAGGAAGTTAAAGACTTTCTGCGTCAGTAT
TCCTGGCCGGGAAATATCCGGGAACTGCATAACACAGTGGAATACTTTGTTTATACCGGTAAACGAGTGATTGATATGAA
TGATTTACCGCCTACTATTTTCCATGACCGGGCATCCAGACCGGTGAATGTGGAGAAGAAGGAGAGACTGCAGGAAGTGA
TTTTGCCATTCTGGTTCGTTCTGGAACAGCTTTATGTGGCAGCAGAGCGGAATGAGTTTATCGGAAGGGATAAGCTGCTG
TTGAAGGCGAAGAAGCAGTATCTTCTATTGTCCCAAAAAGAGATTAGGCATATTTTAAAGGACATGGAGAAAAAAGGTTT
TGTAAAAATCGGAAAAGGAAGAGGCGGCAGCAGGATTACCCTGAAGGGGAAGGAATACTGGCAGAGTCGGGATAAGTCTT
TGGATAAATAG

Upstream 100 bases:

>100_bases
TACATTCTTAAATGATCAAAAAGTTACATTCTAATCTAATCTTGACATTTATACAAAATTGCATTCACTTATTCTTTAAG
CTATAATAAATGTAGGTAAT

Downstream 100 bases:

>100_bases
AAAAACATATAGAAAGAAAGCAGTGCCAAGTTATAATATACTTAGCACTGCCTTTTATAAGTCTTAAATTATAGTGATAA
ATAAATTTTTTATTTATATT

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEISPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICQTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRIVSVDVRIVAATNESLDQKVEEGGFRKDLYYRLNTLTVVVPLLRERGEDVFLLMEHFKEELQGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKRVIDMNDLPPTIFHDRASRPVNVEKKERLQEVILPFWFVLEQLYVAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRHILKDMEKKGFVKIGKGRGGSRITLKGKEYWQSRDKSLDK

Sequences:

>Translated_696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEISPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICQTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRIVSVDVRIVAATNESLDQKVEEGGFRKDLYYRLNTLTVVVPLLRERGEDVFLLMEHFKEELQGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKRVIDMNDLPPTIFHDRASRPVNVEKKERLQEVILPFWFVLEQLYVAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRHILKDMEKKGFVKIGKGRGGSRITLKGKEYWQSRDKSLDK
>Mature_696_residues
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKADLFVISTDAYGSAEEVARHV
PIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMAREAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEER
YVPQSVKKVLNIGHRSCTSGMMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEISPKVIKLGGVNVSIEVIPVLRQKKCIGAFA
TLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCICQTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKR
SKGPFIAINVAAMPENLLESELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
SRIVSVDVRIVAATNESLDQKVEEGGFRKDLYYRLNTLTVVVPLLRERGEDVFLLMEHFKEELQGDFKLSEEVKDFLRQY
SWPGNIRELHNTVEYFVYTGKRVIDMNDLPPTIFHDRASRPVNVEKKERLQEVILPFWFVLEQLYVAAERNEFIGRDKLL
LKAKKQYLLLSQKEIRHILKDMEKKGFVKIGKGRGGSRITLKGKEYWQSRDKSLDK

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=278, Percent_Identity=44.2446043165468, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1789233, Length=259, Percent_Identity=45.1737451737452, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1790299, Length=251, Percent_Identity=49.003984063745, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1790437, Length=269, Percent_Identity=46.0966542750929, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1786524, Length=266, Percent_Identity=44.3609022556391, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI87082117, Length=266, Percent_Identity=44.3609022556391, Blast_Score=212, Evalue=8e-56,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=48.7179487179487, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082152, Length=234, Percent_Identity=48.7179487179487, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1788905, Length=219, Percent_Identity=47.945205479452, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789087, Length=257, Percent_Identity=42.8015564202335, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787583, Length=348, Percent_Identity=32.4712643678161, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI87081858, Length=409, Percent_Identity=26.8948655256724, Blast_Score=149, Evalue=7e-37,
Organism=Escherichia coli, GI1789828, Length=285, Percent_Identity=32.9824561403509, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 78734; Mature: 78734

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKA
CCCHHHCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DLFVISTDAYGSAEEVARHVPIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMA
CEEEEECCCCCCHHHHHHHCCCCCEEEEEEEEEEHHHHHCCCCCCCCCEEEEEECHHHHH
REAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEERYVPQSVKKVLNIGHRSCTSG
HHHHHHHHHCCCCEEEEEECCCCHHHCCCCCCEECCCHHCCCHHHHHHHHHCCCCCCCCC
MMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEISPKVIKLGGV
CCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCC
NVSIEVIPVLRQKKCIGAFATLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCI
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCH
CQTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKRSKGPFIAINVAAMPENLLES
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
ELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
HHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECC
SRIVSVDVRIVAATNESLDQKVEEGGFRKDLYYRLNTLTVVVPLLRERGEDVFLLMEHFK
CEEEEEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
EELQGDFKLSEEVKDFLRQYSWPGNIRELHNTVEYFVYTGKRVIDMNDLPPTIFHDRASR
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCEEEECCCCCCHHHHCCCCC
PVNVEKKERLQEVILPFWFVLEQLYVAAERNEFIGRDKLLLKAKKQYLLLSQKEIRHILK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMEKKGFVKIGKGRGGSRITLKGKEYWQSRDKSLDK
HHHHCCCEEEECCCCCCEEEECCHHHHHHHHCCCCC
>Mature Secondary Structure
MRKLWRNHEGIMKKTMSVVALDARAGEFYAKEINELFGEYVEIASYNVSDGSAVGTLPKA
CCCHHHCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DLFVISTDAYGSAEEVARHVPIDSLTMGIEVSYRWSTLQNLSMIPKGTRALFVNMTDTMA
CEEEEECCCCCCHHHHHHHCCCCCEEEEEEEEEEHHHHHCCCCCCCCCEEEEEECHHHHH
REAIAQLQQLGVNHIRFIPFYPGAVLEEPVDMAVTPEEERYVPQSVKKVLNIGHRSCTSG
HHHHHHHHHCCCCEEEEEECCCCHHHCCCCCCEECCCHHCCCHHHHHHHHHCCCCCCCCC
MMIEIALRMGLEQLLETKKFQNYFQAMATNNYSFNQIYARSRRLESQFHILMEILDEGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVNEKGEIFACNKKACQIAKIAENLVIGRCGEKVFPYIPFYSALKDKKEISPKVIKLGGV
CCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCC
NVSIEVIPVLRQKKCIGAFATLQEFSELESKQNELRSQLLKKGYCAKYTFNDVIGESDCI
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCH
CQTKGILKRMAATESPVLIVGETGTGKELLAHAVHCASKRSKGPFIAINVAAMPENLLES
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHH
ELFGYEEGAFTGAKKGGRPGLFEFAHGGTLFLDEVEGMSQAMQVKLLRVLQEGEVMRVGG
HHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECC
SRIVSVDVRIVAATNESLDQKVEEGGFRKDLYYRLNTLTVVVPLLRERGEDVFLLMEHFK
CEEEEEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
EELQGDFKLSEEVKDFLRQYSWPGNIRELHNTVEYFVYTGKRVIDMNDLPPTIFHDRASR
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCEEEECCCCCCHHHHCCCCC
PVNVEKKERLQEVILPFWFVLEQLYVAAERNEFIGRDKLLLKAKKQYLLLSQKEIRHILK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMEKKGFVKIGKGRGGSRITLKGKEYWQSRDKSLDK
HHHHCCCEEEECCCCCCEEEECCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA