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The map label for this gene is patA [H]

Identifier: 170757046

GI number: 170757046

Start: 3417574

End: 3418743

Strand: Reverse

Name: patA [H]

Synonym: CLD_1381

Alternate gene names: 170757046

Gene position: 3418743-3417574 (Counterclockwise)

Preceding gene: 170757162

Following gene: 170755527

Centisome position: 86.37

GC content: 27.86

Gene sequence:

>1170_bases
ATGGATTATATAAAAGCTGAAGAAATTATTTCGGAAAAAGTTAAAAATATAGAGATTTCTGGTATAAGGAGGTTTTTTAA
CAAAGTTTCAAATTATAAGGATGTTATTTCCTTAACTTTAGGGCAACCAGATTTTAAACTTCCAAATAGAATAAAAGAGG
AATTAGTAAAGTCTATAGAAGAGGATAAAACAACCTATACAGCTAATGCAGGATTAAAAGATTTAAGATTAGAAATAGAA
AAATATCTTAAAACTATGGATATTAATTATAATTCAGAAGAGATATGTATAACTGTAGGTGGTAGTGAAGGATTAATGTG
TGTATTTTCTACATTACTAAATGAAGGAGACAAAGTTTTAATACCAACACCTGCATATCCTGCTTATGAAAGCTGTGTAA
AATTATTAGGTGGACAAATATTAAATTATAAATTAAAAAATGATTTTTCTATAGATTTTTCAGATTTAGAAAATATAATA
GAAAAAGAAAAACCTAAGGTTATGGTATTATCTTATCCGTCTAATCCCACAGGAGCTATACTTTCTAAGGAAGAAAGTTA
TAAGCTATATAATATAATAAAAGAAAACAATATCATAGTAATAAGTGATGAAATATACAGTTCCTTATGTTTTGAAGAGA
AATATTATTCTATAGCTCAGTATGGAGATATAAAAGACAAGGTTATATTAGTTAGTGGATTTTCAAAAATGTTTTCAATG
ACTGGACTTAGAATAGGGTATGTTTGTGCAAATGATGAGTTCATAAATTCTATAATAAAAGTTCATCAATATAATGTATC
TTGTGCGCCTTCTATATGTCAGTGGGGAGCTTATGCAGGATTAAAATACTGTATGGAAGATGTAGCTTATATGAAAGAGG
AATTTATAAAAAGAAGAGATTTTGTATATAATAGACTAAAATACATGGAAATAGATACATATCTTCCTAAGGGAGCTTTT
TATATATTTCCTTCCATAAAAAAATATAATATGACTAGTGAAGAATTTTGTGAAAGACTTTTGAAGGAAGCTAAAGTGGC
TATAGTTCCTGGCTCAGCCTTTGGAGAAATGGGAGAGGGATATATTAGAATATCTTATGCCTATAGCATGGAAGAATTAA
ATGAAGCACTAAACAGAATGGAAGCGTGGTTAAATAAAATCACGATATAA

Upstream 100 bases:

>100_bases
ATGTAAATTTAATAAAACATATTGGTTTTAATATTTTAAAAATATAGAAAGGAAGGAGAGGTTATGGTTTATTAACATTA
CCATAACATGATAATATTTT

Downstream 100 bases:

>100_bases
GGAAATTATGACTTAAAAGGTAGTTTACCTGTGGCCTATTAAAAAGGGATATGTGACGAGATCGGCAAATCAATTCGCTA
AGAGGTTCTAATTTGTTTTT

Product: aminotransferase, classes I and II

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDYIKAEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPNRIKEELVKSIEEDKTTYTANAGLKDLRLEIE
KYLKTMDINYNSEEICITVGGSEGLMCVFSTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRDFVYNRLKYMEIDTYLPKGAF
YIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEAWLNKITI

Sequences:

>Translated_389_residues
MDYIKAEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPNRIKEELVKSIEEDKTTYTANAGLKDLRLEIE
KYLKTMDINYNSEEICITVGGSEGLMCVFSTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRDFVYNRLKYMEIDTYLPKGAF
YIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEAWLNKITI
>Mature_389_residues
MDYIKAEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPNRIKEELVKSIEEDKTTYTANAGLKDLRLEIE
KYLKTMDINYNSEEICITVGGSEGLMCVFSTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRDFVYNRLKYMEIDTYLPKGAF
YIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEAWLNKITI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=398, Percent_Identity=25.8793969849246, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI56713254, Length=398, Percent_Identity=25.8793969849246, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI95147551, Length=404, Percent_Identity=22.029702970297, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI169881279, Length=404, Percent_Identity=22.029702970297, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI4507369, Length=369, Percent_Identity=23.0352303523035, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7705897, Length=390, Percent_Identity=24.3589743589744, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI33469970, Length=390, Percent_Identity=24.3589743589744, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=23.3062330623306, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=23.3062330623306, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI169881281, Length=387, Percent_Identity=20.1550387596899, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI187936925, Length=376, Percent_Identity=23.4042553191489, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI14211921, Length=376, Percent_Identity=23.4042553191489, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=28.9256198347107, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=24.5179063360882, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=26.7379679144385, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790797, Length=391, Percent_Identity=21.7391304347826, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787710, Length=207, Percent_Identity=26.0869565217391, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788332, Length=184, Percent_Identity=24.4565217391304, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=25.8760107816712, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=365, Percent_Identity=25.2054794520548, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=365, Percent_Identity=25.2054794520548, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=367, Percent_Identity=25.3405994550409, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71981209, Length=374, Percent_Identity=25.4010695187166, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=213, Percent_Identity=27.2300469483568, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=298, Percent_Identity=24.496644295302, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323118, Length=425, Percent_Identity=26.3529411764706, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320317, Length=364, Percent_Identity=25.8241758241758, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=24.4845360824742, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=24.4845360824742, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=24.4845360824742, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=24.4845360824742, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24641770, Length=337, Percent_Identity=25.5192878338279, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641760, Length=337, Percent_Identity=25.5192878338279, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641768, Length=337, Percent_Identity=25.5192878338279, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641766, Length=337, Percent_Identity=25.5192878338279, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641764, Length=337, Percent_Identity=25.5192878338279, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45551451, Length=337, Percent_Identity=25.5192878338279, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=22.1354166666667, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 44687; Mature: 44687

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYIKAEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPNRIKEELVKSIE
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHEEEECCCCCCCCCHHHHHHHHHHHH
EDKTTYTANAGLKDLRLEIEKYLKTMDINYNSEEICITVGGSEGLMCVFSTLLNEGDKVL
HCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEE
IPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENIIEKEKPKVMVLSYPSNPTGAI
EECCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCE
LSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
ECCCCCCHHHHEEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHH
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRD
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYNRLKYMEIDTYLPKGAFYIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEG
HHHHHHHEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHCCCCC
YIRISYAYSMEELNEALNRMEAWLNKITI
EEEEEEEECHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYIKAEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPNRIKEELVKSIE
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHEEEECCCCCCCCCHHHHHHHHHHHH
EDKTTYTANAGLKDLRLEIEKYLKTMDINYNSEEICITVGGSEGLMCVFSTLLNEGDKVL
HCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEE
IPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENIIEKEKPKVMVLSYPSNPTGAI
EECCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCE
LSKEESYKLYNIIKENNIIVISDEIYSSLCFEEKYYSIAQYGDIKDKVILVSGFSKMFSM
ECCCCCCHHHHEEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHH
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMEDVAYMKEEFIKRRD
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYNRLKYMEIDTYLPKGAFYIFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEG
HHHHHHHEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHCCCCC
YIRISYAYSMEELNEALNRMEAWLNKITI
EEEEEEEECHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]