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The map label for this gene is endo I [H]

Identifier: 170756935

GI number: 170756935

Start: 859849

End: 861702

Strand: Direct

Name: endo I [H]

Synonym: CLD_0024

Alternate gene names: 170756935

Gene position: 859849-861702 (Clockwise)

Preceding gene: 170756706

Following gene: 170755675

Centisome position: 21.72

GC content: 32.52

Gene sequence:

>1854_bases
ATGAAAAACACCAAATTAATAAAATTAGTAGCTGGTATTATGGCTGCTACATTTTCACTGTCGCTTTTGACAACAAAAGT
AGAGGCAAAAAATATTGAAAATAAAAATACTAAAAATGAAGTTAAACAAACTGTTAATAATAAAGATTTAGAAAGAAAGT
TAATTGGATATTTCCCAGAGTGGGCCTATAATAGTGAAGCTCAAGGGTATTTTAAGGTTACTGATTTGCAATGGGATTCT
TTAACTCATATTCAATATTCCTTTGCAATGGTGGATCAAGCTACAAATAAAATTAAATTAGGGGACAAACATGCCGCACT
GGAAGAGGAATTTAAAAATCATAATTTATCTTATAAAGGGAAAAAGGTAGAGTTAGATCCAAATCTCCCGTATAAAGGAC
ACTTTAATTTATTACAAACTATGAAAAAACAATATCCTGATGTTAATTTGCTTATATCAGTAGGTGGGTGGGCTGGAAGT
AGAGGATTCTATACAATGCTTGATACGGATGAAGGAATAAATACCTTTGCAGATTCTTGCGTTGATTTTATAAAAAAGTA
TAACTTTGATGGTGTTGATATTGACTTTGAATATCCATCTTCAACAAGTCAGTCAGGAAATCCAGCGGATTTTGACTTAT
CTGAACCTAGAAGGGCTAAATTAAATGAGAGATATAATATACTCATGAAAACATTAAGGGAAAAAATAGATGCGGCTTCT
AAAAAGGATAATAAAGATTATATATTATCTGCTGCAGTTACAGCATCACCTTGGGTACTTGGTGGAGTCAAAGATAACAT
CTATGCTAAGTATCTAGATTTCTTAAGTGTTATGTCCTATGACTATCATGGCGGATGGAATGAATATGTTGAAAATTTAG
CAGGTATTTATCCAGATCCAAAAGATAGGGAAACTGCCAGTCAAATCATGCCAACACTTTGTATGGATTGGGCTTATAGA
TATTACAGAGGAGTTTTGCCACCTGAAAAAATATTAATGGGTATACCATACTATACTAGAGGATGGGAAAATGTACAAGG
TGGACAAAATGGACTTCATGGATCAAGTAGGACCCCTGCATCTGGTAAGTATAATATCTGGGGAGACGATTTAGATAACG
ATGGAAAGCTAGAGCCAGCAGGTGCTAACCCATTATGGCATGTATTAAACCTTATGGAAAAAGATAAAAATTTAAAAGTA
TATTGGGATGATGTGGAAAAGGTGCCATATGTTTGGCAAAATCAAGAGAGAGCTTTCTTATCTTTTGAGAATGAAAGATC
TATTGATGAAAGACTTAATTATATTAAAAATAAAAATCTAGGTGGAGCATTAATTTGGGTTATGAACGGTGATTATGGAT
TAAATCCTAATTATGAAGAAGGTTCAAGTGATATAAATAAAGGAAAGTATACTTTCGGTGATACTTTAACTAAGAGATTA
AGTAATGGCTTAACTAATATGGGAGCATGCAGTAAAACAACAGAGGATTCTAATAATTCCCTAGAACCTATAAATGTTTC
AGTGGACTTCGATGGTAGCTATGATCATCCAAATTACACTTATGATATAAAGGTAAAAAATTATACAGGTAAAGAAATTA
AGGGAGGATGGGAAGTATCCTTTGATTTACCAAAATCAGCATTATATAAGTCTTCCTGGGGAGGTAACTACACTTTAAAA
GATAATGGAGATTTTACAACAGTTACAATAAAATCTGGTAACTGGCAAAATATTAATGCTGGTGCTACCGTTAATCTCCA
AGGGATGATAGGACTATGCTTTTCAGATGTTAGAAATATTAAATTTAATGGTATGAAACCTGTAGGAAATCAAAAAATTA
TTCAACAAAAATAG

Upstream 100 bases:

>100_bases
AGTTACTGAGACAATATAGCCCAAATTCATATTTGAAACCAAATAGCAAGATTATCATAGCATAGTATTATAATATAGAA
ATAAAATAGGAGGATTTACA

Downstream 100 bases:

>100_bases
AGATAGAAAATTAAATTATAAAGAAAAGTAAAATAAAACAGTGCCTATGTATTTTATAATGCTAAGCACTGTTTTATTTG
ATTAAAAGGATGAAATCATA

Product: glycosy hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNNKDLERKLIGYFPEWAYNSEAQGYFKVTDLQWDS
LTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNHNLSYKGKKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGS
RGFYTMLDTDEGINTFADSCVDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
KKDNKDYILSAAVTASPWVLGGVKDNIYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDPKDRETASQIMPTLCMDWAYR
YYRGVLPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPASGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDKNLKV
YWDDVEKVPYVWQNQERAFLSFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
SNGLTNMGACSKTTEDSNNSLEPINVSVDFDGSYDHPNYTYDIKVKNYTGKEIKGGWEVSFDLPKSALYKSSWGGNYTLK
DNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNIKFNGMKPVGNQKIIQQK

Sequences:

>Translated_617_residues
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNNKDLERKLIGYFPEWAYNSEAQGYFKVTDLQWDS
LTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNHNLSYKGKKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGS
RGFYTMLDTDEGINTFADSCVDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
KKDNKDYILSAAVTASPWVLGGVKDNIYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDPKDRETASQIMPTLCMDWAYR
YYRGVLPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPASGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDKNLKV
YWDDVEKVPYVWQNQERAFLSFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
SNGLTNMGACSKTTEDSNNSLEPINVSVDFDGSYDHPNYTYDIKVKNYTGKEIKGGWEVSFDLPKSALYKSSWGGNYTLK
DNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNIKFNGMKPVGNQKIIQQK
>Mature_617_residues
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNNKDLERKLIGYFPEWAYNSEAQGYFKVTDLQWDS
LTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNHNLSYKGKKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGS
RGFYTMLDTDEGINTFADSCVDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
KKDNKDYILSAAVTASPWVLGGVKDNIYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDPKDRETASQIMPTLCMDWAYR
YYRGVLPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPASGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDKNLKV
YWDDVEKVPYVWQNQERAFLSFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
SNGLTNMGACSKTTEDSNNSLEPINVSVDFDGSYDHPNYTYDIKVKNYTGKEIKGGWEVSFDLPKSALYKSSWGGNYTLK
DNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNIKFNGMKPVGNQKIIQQK

Specific function: Hydrolyzes chitin oligosaccharides; (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5,6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin, glucosamine oligosaccharides, glycoproteins and glycopeptides containing (GlcNAc)2 [H]

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 18 family [H]

Homologues:

Organism=Homo sapiens, GI4502809, Length=437, Percent_Identity=27.2311212814645, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI58386720, Length=409, Percent_Identity=25.1833740831296, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI133893286, Length=461, Percent_Identity=24.9457700650759, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI68533255, Length=415, Percent_Identity=24.578313253012, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI68533253, Length=415, Percent_Identity=24.578313253012, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI42542398, Length=347, Percent_Identity=25.6484149855908, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI144226251, Length=403, Percent_Identity=22.8287841191067, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI68533260, Length=333, Percent_Identity=25.8258258258258, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71995504, Length=413, Percent_Identity=28.0871670702179, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17559362, Length=405, Percent_Identity=28.8888888888889, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17563680, Length=403, Percent_Identity=27.2952853598015, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17551250, Length=488, Percent_Identity=23.7704918032787, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17535565, Length=333, Percent_Identity=28.2282282282282, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17531695, Length=442, Percent_Identity=23.9819004524887, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17535567, Length=314, Percent_Identity=27.7070063694268, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535569, Length=467, Percent_Identity=26.9807280513919, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI32564165, Length=485, Percent_Identity=23.9175257731959, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536195, Length=317, Percent_Identity=27.1293375394322, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17531683, Length=312, Percent_Identity=24.0384615384615, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320579, Length=395, Percent_Identity=23.5443037974684, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330815, Length=474, Percent_Identity=27.6371308016878, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24655584, Length=409, Percent_Identity=25.6723716381418, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45550474, Length=406, Percent_Identity=26.6009852216749, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21358195, Length=406, Percent_Identity=25.615763546798, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI116007452, Length=407, Percent_Identity=24.0786240786241, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI22024049, Length=402, Percent_Identity=23.8805970149254, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221329807, Length=413, Percent_Identity=21.5496368038741, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI161077700, Length=413, Percent_Identity=21.5496368038741, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24640248, Length=417, Percent_Identity=25.1798561151079, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573679, Length=411, Percent_Identity=23.3576642335766, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003610
- InterPro:   IPR009470
- InterPro:   IPR011583
- InterPro:   IPR001223
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF02839 CBM_5_12; PF06483 ChiC; PF00704 Glyco_hydro_18 [H]

EC number: =3.2.1.14 [H]

Molecular weight: Translated: 69909; Mature: 69909

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNNKDLERKLIGYFPE
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCC
WAYNSEAQGYFKVTDLQWDSLTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNHNLSYKG
CCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCC
KKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGSRGFYTMLDTDEGINTFADSC
CEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
VDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KKDNKDYILSAAVTASPWVLGGVKDNIYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDP
CCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
KDRETASQIMPTLCMDWAYRYYRGVLPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCHHCCCCCCCCCCCCCCCCCCCCC
SGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDKNLKVYWDDVEKVPYVWQNQERAFL
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEECCCCCEEE
SFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
EECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
SNGLTNMGACSKTTEDSNNSLEPINVSVDFDGSYDHPNYTYDIKVKNYTGKEIKGGWEVS
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEE
FDLPKSALYKSSWGGNYTLKDNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNI
ECCCHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCCC
KFNGMKPVGNQKIIQQK
EECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNNKDLERKLIGYFPE
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCC
WAYNSEAQGYFKVTDLQWDSLTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNHNLSYKG
CCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCC
KKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGSRGFYTMLDTDEGINTFADSC
CEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
VDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KKDNKDYILSAAVTASPWVLGGVKDNIYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDP
CCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
KDRETASQIMPTLCMDWAYRYYRGVLPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCHHCCCCCCCCCCCCCCCCCCCCC
SGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDKNLKVYWDDVEKVPYVWQNQERAFL
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEECCCCCEEE
SFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
EECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
SNGLTNMGACSKTTEDSNNSLEPINVSVDFDGSYDHPNYTYDIKVKNYTGKEIKGGWEVS
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEE
FDLPKSALYKSSWGGNYTLKDNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNI
ECCCHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCCC
KFNGMKPVGNQKIIQQK
EECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969204 [H]