Click here to switch to the map view.

The map label for this gene is nagA

Identifier: 170756790

GI number: 170756790

Start: 3027356

End: 3028498

Strand: Reverse

Name: nagA

Synonym: CLD_1740

Alternate gene names: 170756790

Gene position: 3028498-3027356 (Counterclockwise)

Preceding gene: 170755798

Following gene: 170756475

Centisome position: 76.51

GC content: 30.18

Gene sequence:

>1143_bases
ATGAAGGCTATAGTCAATGGAAAGATTATAATAGGTAATGAAATATTAGAAAATAAAGTCTTGTTATTTGAAAAAAAGAT
AGTTGATATATTAGATAGAAAGAATATTTATTTAAGTAAGGATTACCAGATTATTGATGCTAAAGGACTATATGTTTCTC
CAGGATTTATAGACGTTCATATACACGGCTCAGGTGGAAAAGATGTTATGGATGGAGAGCTAGAGTCTATAAGAATTATA
AGCAATACTATAACTAAAAGAGGTGTGACCTCATTTTTACCAACTACTATGACTATGGCTAAAGAACATATATATAAGGC
CTTAGATGTTATAAAACAGGCCATGAACATGGATTTAGGTGGTGCTAAGGTTTTAGGAGCACACTTAGAAGGTCCTTTTA
TTAATCCAAAATATAAAGGGGCTCAAAAGGAGGACTTTATAAAGAATCCAAGCTTTGATTTTATTAAAGGTTATGAGAAT
GTAATAAAAATAATTACTTTAGCCCCAGAGAAAGACGAGAATTTTCAGTTTTTAAAGGATATTAAGGAAAATACAGATAT
AGTTTTATCTATAGGACATTCAGATGCAACCTATGAGCAGGCTATGGCTGCTATAGATAATGGAATAAGTCGTGCTACGC
ATACTTTTAATGCCATGACTCCTTTAAATCATAGAAAACCGGGAATAATAGGTGCTATTATGAATACTGATATATCTTGC
GAACTTATAGCGGATAATATTCATGTTCATAAGGGAGCTGTTAATATTCTTACTAAAATTAAAGGTAAAGATAAGATTAT
TTTAATTACAGATTCAATGAGAGCCGGATGTATGAACAATGGTATATGGGAACTAGGAGGACAGAAAGTTATTGTAAAAA
ATGGTTCTGCTAGATTAGAGGATAATACTTTAGCGGGAAGTATTTTGACTTTAGATAATGCAGTTAAGAATATGAAAAAT
AATATAGAAGCTTCTCTATGTGAAGTTATATCTATGGTAACAGTTAATCCAGCCAAGGATATAAATATATATGACAGAAA
AGGAAGTATTGAAAAAGGAAAAGATGCTGATATTGTTATTTTTGATAAAGACATTAATATTAGTATGACAATTGTTGATG
GAAATATTGTTTATAAAAAATGA

Upstream 100 bases:

>100_bases
CTAATATAATGGATAATGTTAAAGATATAAGTAATAAGCTAAAAGAGCAAGTCTATTATCCTTTAAAAAGCTAATATTTT
TAGATATGAGGTGATCAAAT

Downstream 100 bases:

>100_bases
AGTATTATGACTTAAATTATTAGACACAATTAGTTATTGATTTAATAAAAGAGAAATTTAAATTTTAATGAGGTGTGTTT
TTATGAGAATTATAGTAGTG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKAIVNGKIIIGNEILENKVLLFEKKIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVHIHGSGGKDVMDGELESIRII
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLGGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYEN
VIKIITLAPEKDENFQFLKDIKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGIWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVYKK

Sequences:

>Translated_380_residues
MKAIVNGKIIIGNEILENKVLLFEKKIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVHIHGSGGKDVMDGELESIRII
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLGGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYEN
VIKIITLAPEKDENFQFLKDIKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGIWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVYKK
>Mature_380_residues
MKAIVNGKIIIGNEILENKVLLFEKKIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVHIHGSGGKDVMDGELESIRII
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLGGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYEN
VIKIITLAPEKDENFQFLKDIKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGIWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVYKK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=416, Percent_Identity=27.8846153846154, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI224922791, Length=416, Percent_Identity=28.125, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1786892, Length=389, Percent_Identity=33.4190231362468, Blast_Score=199, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17553768, Length=373, Percent_Identity=31.9034852546917, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI19920392, Length=395, Percent_Identity=30.379746835443, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281361140, Length=409, Percent_Identity=30.0733496332518, Blast_Score=180, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41889; Mature: 41889

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVNGKIIIGNEILENKVLLFEKKIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVH
CCEEECCEEEECCHHHCCCEEEHHHHHHHHHCCCCEEEECCEEEEECCCEEECCCEEEEE
IHGSGGKDVMDGELESIRIISNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLG
EECCCCCCCCCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYENVIKIITLAPEKDENFQFLKD
CCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHEEEEEEECCCCCCCHHHHHH
IKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
HHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCEEEEEECCCCEE
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGIWELGGQKVIVKNGSARLE
EEEECCEEEECCHHEEHHEECCCCEEEEEECCCCCCCCCCCEEECCCCEEEEECCCCEEC
DNTLAGSILTLDNAVKNMKNNIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEE
FDKDINISMTIVDGNIVYKK
EECCCEEEEEEEECEEEEEC
>Mature Secondary Structure
MKAIVNGKIIIGNEILENKVLLFEKKIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVH
CCEEECCEEEECCHHHCCCEEEHHHHHHHHHCCCCEEEECCEEEEECCCEEECCCEEEEE
IHGSGGKDVMDGELESIRIISNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLG
EECCCCCCCCCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYENVIKIITLAPEKDENFQFLKD
CCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHEEEEEEECCCCCCCHHHHHH
IKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
HHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCEEEEEECCCCEE
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGIWELGGQKVIVKNGSARLE
EEEECCEEEECCHHEEHHEECCCCEEEEEECCCCCCCCCCCEEECCCCEEEEECCCCEEC
DNTLAGSILTLDNAVKNMKNNIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEE
FDKDINISMTIVDGNIVYKK
EECCCEEEEEEEECEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]