Click here to switch to the map view.

The map label for this gene is ubiE [C]

Identifier: 170756710

GI number: 170756710

Start: 882046

End: 882699

Strand: Direct

Name: ubiE [C]

Synonym: CLD_3800

Alternate gene names: 170756710

Gene position: 882046-882699 (Clockwise)

Preceding gene: 170755886

Following gene: 170757534

Centisome position: 22.28

GC content: 31.65

Gene sequence:

>654_bases
ATGAGTGATTTAAAGAAGATGAGTGATTCTAAAAAGATAAGTAATTTTAAAAAGGTAGATGTTAGAAATGCTGTTCGTAA
TAGTTATAGAAAGATAGCTATTGGAAATGCAAAAGAGGATGGCTGCTGTGGTGGAAGTATTAATCTTAAAAAATCTTCCA
TAGAGATATCACGTAAGATTGGATATTCTAATGAAGAAATATCAACTGTTCCAGAGGAAGCTAATATGGGATTAGGTTGT
GGAAATCCCCAATTAATAGCTAATATTAAAGAAGGGGAGACTGTTATAGACCTTGGAAGTGGAGGAGGATTTGACTGTTT
TTTAGCTTCAAAGAAAGTTGGGGTTAAGGGATATATTATTGGAGTTGACATGACTCCAGAGATGATTAGTAAATCAAGAA
TTATGTCTAGGAAATATAGGTATAGAAATGTAGACTTTAGATTAGGTGAAATTGAAAATCTTCCTGTAGCAGATAATACC
GCGGATGTAATTATTTCAAATTGTGTTATAAATTTATCTCCCAATAAACAAAGAGTATATAATGAAGCTTATCGTGTATT
AAAAAAAGGTGGTAGAATTGCTATTTCTGATATAGTTCTTATTAGAGAATTAACCAAGGAGATGAAGCAAGATGAGAAAC
TTTATTGTGGATGA

Upstream 100 bases:

>100_bases
AATGAAGTTTTATAAAAGAAGTTTGGATAGTACCTAAGAACCTTACGACTTTAGTCGTGAGAGGTTCAGCACTGGATAGT
TAAAGTAGGGAGGAAAAAAG

Downstream 100 bases:

>100_bases
GTTACTGGGGCATCTTCAGTTGAAGAGTTAAAATTATATTTAGAAAAGGCTGGTTTTAGTGATATTAAAATTGAAACTAA
AGAAGTCTCAAAGGAATATG

Product: UbiE/COQ5 family methlytransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Arsenite S-Adenosylmethyltransferase; Methyltransferase; Arsenite Methyltransferase; SAM-Dependent Methyltransferase; UbiE/COQ5 Methyltransferase; Methyltransferase-Like; UbiE/COQ5 Family Methlytransferase; Methyltransferase Domain Family; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; Arsenic Methyltransferase; 2-Heptaprenyl-1 4-Naphthoquinone Methyltransferase; Protein Containing Methyltransferase Domain; ArsR Family Transcriptional Regulator; SAM-Dependent Methyltransferases; Cyclopropane-Fatty-Acyl-Phospholipid Synthase; Methyltransferase UbiE/COQ5 Family; Methyltransferase UbiE-Family; Radical SAM Domain-Containing Protein; Transcriptional Regulator ArsR Family; Methyltransferase Domain Family Protein

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSDLKKMSDSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSNEEISTVPEEANMGLGC
GNPQLIANIKEGETVIDLGSGGGFDCFLASKKVGVKGYIIGVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNT
ADVIISNCVINLSPNKQRVYNEAYRVLKKGGRIAISDIVLIRELTKEMKQDEKLYCG

Sequences:

>Translated_217_residues
MSDLKKMSDSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSNEEISTVPEEANMGLGC
GNPQLIANIKEGETVIDLGSGGGFDCFLASKKVGVKGYIIGVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNT
ADVIISNCVINLSPNKQRVYNEAYRVLKKGGRIAISDIVLIRELTKEMKQDEKLYCG
>Mature_216_residues
SDLKKMSDSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSNEEISTVPEEANMGLGCG
NPQLIANIKEGETVIDLGSGGGFDCFLASKKVGVKGYIIGVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTA
DVIISNCVINLSPNKQRVYNEAYRVLKKGGRIAISDIVLIRELTKEMKQDEKLYCG

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109389364, Length=161, Percent_Identity=39.1304347826087, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 24014; Mature: 23883

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKKMSDSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKI
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEHHHEEHHHHC
GYSNEEISTVPEEANMGLGCGNPQLIANIKEGETVIDLGSGGGFDCFLASKKVGVKGYII
CCCCCHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCEEEEE
GVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTADVIISNCVINLSPNKQRVY
EECCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHEEEEEEEEEECCCHHHHH
NEAYRVLKKGGRIAISDIVLIRELTKEMKQDEKLYCG
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDLKKMSDSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKI
CHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEHHHEEHHHHC
GYSNEEISTVPEEANMGLGCGNPQLIANIKEGETVIDLGSGGGFDCFLASKKVGVKGYII
CCCCCHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCEEEEE
GVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTADVIISNCVINLSPNKQRVY
EECCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHEEEEEEEEEECCCHHHHH
NEAYRVLKKGGRIAISDIVLIRELTKEMKQDEKLYCG
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA