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The map label for this gene is glpX

Identifier: 170756632

GI number: 170756632

Start: 2795815

End: 2796789

Strand: Reverse

Name: glpX

Synonym: CLD_1949

Alternate gene names: 170756632

Gene position: 2796789-2795815 (Counterclockwise)

Preceding gene: 170755013

Following gene: 170754842

Centisome position: 70.66

GC content: 36.31

Gene sequence:

>975_bases
ATGCTAAATACAGATATTGCTATGGGACTTGCTAGAGTAACAGAAGCAGCAGCGTTAAGTGCATCAAAATTTATGGGTAG
AGGAGACAAAAATGCGGCGGATCAAGCAGCAGTGGATGGCATGCACAAAGCTTTTCAAATAATGCCCATAAGAGGTAAGG
TTGTTATAGGAGAAGGAGAATTAGATGAGGCTCCTATGCTATATATAGGTGAAGAAGTTGGAATTGGTGCAGAGGATATG
GTAGAAATGGATATAGCTGTAGATCCAGTAGATGGAACTAAACTTATAGCAAAGGGTTTAGAAAATGCTATAGCCGTGGT
AGCTATGGGACCTAAAGGAAGTTTATTTCATGCACCAGATATGTATATGAAGAAAATAGCTGTAGGAGCAGGGGCTAAGG
GAGCTATAGATATAAATAAATCCCCTAAAGAGAATATATTAAATGTAGCTAGAGCTCTAAATAAAGATGTAACAGAACTT
ACAGTTATAGTTCAAGAAAGAGATAGACATGATTATATAGTAAAAGATGCAAGAGAAGTAGGCGCTAGAGTTAAGCTTTT
TGGAGAAGGAGATGTAGCAGCAGTATTAGCCTGTGGATTTGAAGATACTGGAGTAGATATAATGATGGGAACCGGTGGAG
CTCCAGAAGGTGTTATAGCAGCAGCTGCCATAAAATGTATGGGCGGTGAAATACAAGCACAACTTTGTCCAACTAGTCAA
GAAGAAATAGAAAGATGTAAGACTATGGGAATAAAAGATCATGAAGCTATACTTTATATAGATGATTTAGTAAAAAGTGA
TGATGTTTATTTTGCAGCTACAGCTATAACAGATTGTGATTTGTTAAAGGGAGTAGTTTACAATAGAAATGAGAAGGCTA
TTACAAATTCTATAGTTATGAGATCTAAAACTGGTACTATTAGATTTGTTAAAGCTTGTCATAACTTAGCTAAAAGCGCT
ATAGTAGTTGAATAA

Upstream 100 bases:

>100_bases
ATATGATATGCTAATTAAGAGATTTTAATGAAATAAAAGTAAAAAATATATATAAATTATTATTTGTATACAATAAACCA
TGATTTGAGGGGGAAAATAT

Downstream 100 bases:

>100_bases
AATAATCTAAAAAATTAATTTAGTTCTTTAATGATCCTTATATATAAGAGTATGTATTAAACTCCATTATGGCTTAATAC
ATACTCTTTTAATTTATAGA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGELDEAPMLYIGEEVGIGAEDM
VEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPDMYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTEL
TVIVQERDRHDYIVKDAREVGARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEIQAQLCPTSQ
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVMRSKTGTIRFVKACHNLAKSA
IVVE

Sequences:

>Translated_324_residues
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGELDEAPMLYIGEEVGIGAEDM
VEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPDMYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTEL
TVIVQERDRHDYIVKDAREVGARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEIQAQLCPTSQ
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVMRSKTGTIRFVKACHNLAKSA
IVVE
>Mature_324_residues
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGELDEAPMLYIGEEVGIGAEDM
VEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPDMYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTEL
TVIVQERDRHDYIVKDAREVGARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEIQAQLCPTSQ
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVMRSKTGTIRFVKACHNLAKSA
IVVE

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=330, Percent_Identity=44.5454545454545, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI1789298, Length=323, Percent_Identity=42.4148606811146, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34417; Mature: 34417

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEECCEEEECCCC
LDEAPMLYIGEEVGIGAEDMVEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPD
CCCCCEEEECCCCCCCHHHHEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCEEECCH
MYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTELTVIVQERDRHDYIVKDAREV
HHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHC
GARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEIQAQLCPTSQ
CCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCH
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVM
HHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHEEE
RSKTGTIRFVKACHNLAKSAIVVE
ECCCCCHHHHHHHHHHHHCCEECC
>Mature Secondary Structure
MLNTDIAMGLARVTEAAALSASKFMGRGDKNAADQAAVDGMHKAFQIMPIRGKVVIGEGE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEECCEEEECCCC
LDEAPMLYIGEEVGIGAEDMVEMDIAVDPVDGTKLIAKGLENAIAVVAMGPKGSLFHAPD
CCCCCEEEECCCCCCCHHHHEEEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCEEECCH
MYMKKIAVGAGAKGAIDINKSPKENILNVARALNKDVTELTVIVQERDRHDYIVKDAREV
HHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHC
GARVKLFGEGDVAAVLACGFEDTGVDIMMGTGGAPEGVIAAAAIKCMGGEIQAQLCPTSQ
CCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCH
EEIERCKTMGIKDHEAILYIDDLVKSDDVYFAATAITDCDLLKGVVYNRNEKAITNSIVM
HHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHEEE
RSKTGTIRFVKACHNLAKSAIVVE
ECCCCCHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]