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The map label for this gene is expZ [H]

Identifier: 170756628

GI number: 170756628

Start: 3065255

End: 3066733

Strand: Reverse

Name: expZ [H]

Synonym: CLD_1709

Alternate gene names: 170756628

Gene position: 3066733-3065255 (Counterclockwise)

Preceding gene: 170756276

Following gene: 170754770

Centisome position: 77.48

GC content: 31.98

Gene sequence:

>1479_bases
ATGTCTTTAATAAATGTTACAAACCTAACCTTTGCTTATGAAGGTAGCTATGATAATATTTTTGAAAATGTAAGTTTTCA
AATTGATACCGATTGGAAATTGGGCTTCACTGGAAGAAATGGAAGAGGAAAGACTACTTTTCTAAATCTTTTGCTTGAGA
AATACGAATATAATGGAAACATTTCAGCTGATATGACTTTTGAATATTTTCCTTATGAGGTGCAGGAGCAGAGCAATTTC
ACCATAGATATCATAAGGGAGATTAGTCCAAATTCAATGGATTGGGAAATAGTAAAAGAATTATCTTTGTTAGATATGGA
CTACGATGCTTTATATAGACAGTTTTATACACTATCTAAAGGAGAGCAGACTAAAGCACTGTTGGCTGCTATGTTTTTGA
AGGAGAGCTCCTTCTTGCTTATTGATGAGCCTACCAATCATTTGGATGCTGAAGCTAGGCAAAAACTAAGTAATTACTTG
AAAAAAAAGAAAGGATTTATTCTGATTTCACATGATAGGTCTTTTCTGGATAATTGTGTTGACCATATCTTGTCTATTAA
TAAAACTAATATTGAAATACAAAAAGGAAATTTTTCTTCATTGTGGAGAAACAAAGAATTACAAGATGGTTTTGAGCTAG
CAGAAAACGAAAAATTGAAAAAAGATATTAACAGACTTTCAAGCTCGGCAAAGCGTACATCTACGTGGTCAGATAGTGTT
GAAGGCAGCAAGCATGGAACTACCAATTCTGGGAGCAAATTAGATAAAGGATATGTTGGACATAAAGCTGCAAAAATGAT
GAAGCGTGCTAAAAATATAGAAGCTAGACAACAAAACATGATTGAGGAAAAATCAAAGCTTCTTAAAAATATTGAATCTA
ATGAAAGTTTAAAAATAGTACCGCTTACTTTCCATGATAAAAAGCTTGTAGAACTTACAGATGTTGCAATTGAATATGAT
GATAGAATTGTCTGTGAAGGAGTAAGCTTCACTATAGAGCAAGGTGAAAGAATTGCTATTCAAGGAAAGAATGGCAGCGG
AAAATCAAGTATATTGAAATTAATCTATGGAGAAGACATCCCCCATAGTGGAATTGTAAGAAAGAATAATAAGTTAATCA
TTTCGTATGTTTCACAAGATACTTCAGATTTATATGGTAATTTATCTGAATATGCAGATAAACACTGTATTGACGAGAGT
TTATTTAAATCGATACTTAGAAAGCTTGATTTTTCAAGAGAACAGTTTGAAAAGAATATCGAGGATTTTAGTGGAGGACA
GAAGAAAAAGGTATTGATTGCCGAAAGTTTGTGTGAACAGGCACATTTGTATATTTGGGATGAACCATTGAATTTTATTG
ATGTCATTTCTCGTATGCAGATTGAGAAATTGTTAATTGAACATGAACCTACAATTTTGTTTATTGAGCATGATAGTGCA
TTTTGTGAAAATGTTGCAACAAAAACAATAAAATTGTAA

Upstream 100 bases:

>100_bases
AGTCGGATATTGCAGGCGACACTTATATGGAGTAATAACAAAGTCGCCTATTGTTCCGACTTTGTTATTTATACTATTAA
ATACAGAGGAGGACAAAAAT

Downstream 100 bases:

>100_bases
AGGTAGAAATGGCGATTAATATGTTTAATGGGAATATGAAAGTAACACACAATAGGCTCCATGCAAAGCCAGATGTTTTG
GGCGACGCTTGCATGGAGTA

Product: drug resistance ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLEKYEYNGNISADMTFEYFPYEVQEQSNF
TIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYL
KKKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSLWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYD
DRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDES
LFKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAESLCEQAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
FCENVATKTIKL

Sequences:

>Translated_492_residues
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLEKYEYNGNISADMTFEYFPYEVQEQSNF
TIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYL
KKKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSLWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYD
DRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDES
LFKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAESLCEQAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
FCENVATKTIKL
>Mature_491_residues
SLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLEKYEYNGNISADMTFEYFPYEVQEQSNFT
IDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSKGEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLK
KKKGFILISHDRSFLDNCVDHILSINKTNIEIQKGNFSSLWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSVE
GSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIVPLTFHDKKLVELTDVAIEYDD
RIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDIPHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDESL
FKSILRKLDFSREQFEKNIEDFSGGQKKKVLIAESLCEQAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSAF
CENVATKTIKL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27881506, Length=526, Percent_Identity=23.7642585551331, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI148612853, Length=537, Percent_Identity=23.6499068901304, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI10947137, Length=526, Percent_Identity=23.7642585551331, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI10947135, Length=400, Percent_Identity=25.5, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI69354671, Length=400, Percent_Identity=25.5, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI157502203, Length=201, Percent_Identity=29.3532338308458, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI157502201, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI90421313, Length=184, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=25.1417769376182, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789751, Length=505, Percent_Identity=25.5445544554455, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=25.4752851711027, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787182, Length=547, Percent_Identity=23.9488117001828, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789962, Length=197, Percent_Identity=26.3959390862944, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081709, Length=198, Percent_Identity=25.7575757575758, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=519, Percent_Identity=22.3506743737958, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17555318, Length=381, Percent_Identity=25.9842519685039, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17553372, Length=508, Percent_Identity=24.0157480314961, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320874, Length=539, Percent_Identity=20.5936920222635, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321121, Length=385, Percent_Identity=24.1558441558442, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325030, Length=186, Percent_Identity=27.4193548387097, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24641342, Length=529, Percent_Identity=26.2759924385633, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24642252, Length=538, Percent_Identity=23.6059479553903, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859989, Length=538, Percent_Identity=23.6059479553903, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24666836, Length=519, Percent_Identity=22.5433526011561, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI45550390, Length=173, Percent_Identity=26.5895953757225, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 56498; Mature: 56367

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLEKYEYNGN
CCEEEEEEEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHCCCC
ISADMTFEYFPYEVQEQSNFTIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSK
CCEEEEEEECCCEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLKKKKGFILISHDRSFLDNCV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
DHILSINKTNIEIQKGNFSSLWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
HHHHCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCC
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PLTFHDKKLVELTDVAIEYDDRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDI
EEEECCCHHEEHHHEEEECCCEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHEECCCC
PHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDESLFKSILRKLDFSREQFEKNI
CCCCEEECCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EDFSGGQKKKVLIAESLCEQAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
HHHCCCCCEEEHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHH
FCENVATKTIKL
HHHHHHHHHCCC
>Mature Secondary Structure 
SLINVTNLTFAYEGSYDNIFENVSFQIDTDWKLGFTGRNGRGKTTFLNLLLEKYEYNGN
CEEEEEEEEEEEECCHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHCCCC
ISADMTFEYFPYEVQEQSNFTIDIIREISPNSMDWEIVKELSLLDMDYDALYRQFYTLSK
CCEEEEEEECCCEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GEQTKALLAAMFLKESSFLLIDEPTNHLDAEARQKLSNYLKKKKGFILISHDRSFLDNCV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHH
DHILSINKTNIEIQKGNFSSLWRNKELQDGFELAENEKLKKDINRLSSSAKRTSTWSDSV
HHHHCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCC
EGSKHGTTNSGSKLDKGYVGHKAAKMMKRAKNIEARQQNMIEEKSKLLKNIESNESLKIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PLTFHDKKLVELTDVAIEYDDRIVCEGVSFTIEQGERIAIQGKNGSGKSSILKLIYGEDI
EEEECCCHHEEHHHEEEECCCEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHEECCCC
PHSGIVRKNNKLIISYVSQDTSDLYGNLSEYADKHCIDESLFKSILRKLDFSREQFEKNI
CCCCEEECCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EDFSGGQKKKVLIAESLCEQAHLYIWDEPLNFIDVISRMQIEKLLIEHEPTILFIEHDSA
HHHCCCCCEEEHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHH
FCENVATKTIKL
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]