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The map label for this gene is trkH

Identifier: 170756451

GI number: 170756451

Start: 1458044

End: 1459489

Strand: Direct

Name: trkH

Synonym: CLD_3240

Alternate gene names: 170756451

Gene position: 1458044-1459489 (Clockwise)

Preceding gene: 170757426

Following gene: 170755999

Centisome position: 36.84

GC content: 31.12

Gene sequence:

>1446_bases
ATGAACTACCCAATAGTATTTAAAGTATTAGGAGATGTAATAAAATATGAAGCTTTAGTTATGATATTTCCTCTTATAGC
ATCCTTATATTATGGTGGCAAAGATGCTAATAGTTTTATAATAACTATTGCAATAATGCTGTGTACTGCAGTTATAATGT
CAAATATTAGACCTAAAAATAGAACTTTTTATGCTAAAGAAGGTTTTTTATCTGTTTCTGTTTGTTGGATAGTTATATCT
TTATTTGGAGCATTACCATTTTATATAAGTGGAGCGATACCTTCCTTTGTAGATTGTATATTTGAAACAGTGTCAGGCTT
TACAACTACGGGAGCTACTATTTTAACAGAAGTAGAATCTTTACCTAGGGGAATATTGTTTTGGAGAAGCTTTACACATT
GGATAGGTGGTATGGGAATATTAATATTTACATTAGCATTAATGCCTTCTATAGGTGGTACTACAATTCATCTTTTAAAG
GCAGAAAGTCCAGGGCCTACTCCAGGGAAAATTGTTCCAAGGATAAAAGAAACAGCTAAAATAATGTATTTAATATATTT
TGCTATGACTATATTACAAATAAGTTTACTTTTAATTGCAGGGATGGAACCTTATGATGCATTAATACATGCCTTTGGTA
CAGCTGGTACTGGAGGGTTTTCCAGTATGAATAGTAGTGTAGGAGCATATAATAATGTATATATAGAAGTTATAATAACA
GTGTTTATGTTATTGTTCGGTGTTAATTTTAATGTATATTTTCAACTAATAGCAGGAAATATTAAACAAGCTTTTAAAAA
TGAAGAAGTGAAATATTATATAGGTATGGTATTGATTGCTATGACAATAATAGCTTTTAATATTAAAGGAATGTATGGGG
GATCTTTAAAGGAAGGTTTTAGGCAATCATCTTTCCAAGTAGCCTCTATTGTAACGACTACAGGTTATGCTACTACTAAT
TTTGATTTGTGGCCAACCCTTAGTAAATCAATATTAGCTTTATTAATGCTTACAGGATGTTGTGCAGGTTCTACCGGTGG
GGGAATTAAAACTGTTCGTATAGTACTTTTGTTTAAAGCTATGAAAAGAGAAATAAGTAAAATTATTCATCCTAGAATGG
TTAATTCAGTAAAACTAGATGGTAAGGCTGTAGAGGATGAAACCATATCGCAGGTTGGATTATTTGTATTTGCCTACGTT
AGTATAATTATAATAGCAGTACTTTTAGTATCTATAGATGGTATGGATATGGAGACCACACTTTCTTCTGTGCTTGCAAC
TATAGGTAATATAGGACCTGGTTTTAAGGTGGTAGGACCTATAGGCAATTTTAGTAGCTATTCATCTTTTAGCAAAATAG
TATTTTCATTTTGTATGTTAGCAGGAAGATTAGAAATATATCCAATGCTAGTAATGTTAAGTCCTTCGAGAATGAGAAAA
ATATAA

Upstream 100 bases:

>100_bases
ATGGAGAGGATTCCATAAAAGATGGTGATAATGTCATTATAGTAACGGAAGAAAATAATATAATGGATATTAATAATATA
CTAGAGGGAGGAAACTTAAT

Downstream 100 bases:

>100_bases
TATAGTTTAACTGATAGTAATAGAAAAGTAGCAGATAGATTTAATTTTAAAAGCACAAATATAAAAAATATACTTCATAT
ATCTTACTTATATGTTTATT

Product: Trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNYPIVFKVLGDVIKYEALVMIFPLIASLYYGGKDANSFIITIAIMLCTAVIMSNIRPKNRTFYAKEGFLSVSVCWIVIS
LFGALPFYISGAIPSFVDCIFETVSGFTTTGATILTEVESLPRGILFWRSFTHWIGGMGILIFTLALMPSIGGTTIHLLK
AESPGPTPGKIVPRIKETAKIMYLIYFAMTILQISLLLIAGMEPYDALIHAFGTAGTGGFSSMNSSVGAYNNVYIEVIIT
VFMLLFGVNFNVYFQLIAGNIKQAFKNEEVKYYIGMVLIAMTIIAFNIKGMYGGSLKEGFRQSSFQVASIVTTTGYATTN
FDLWPTLSKSILALLMLTGCCAGSTGGGIKTVRIVLLFKAMKREISKIIHPRMVNSVKLDGKAVEDETISQVGLFVFAYV
SIIIIAVLLVSIDGMDMETTLSSVLATIGNIGPGFKVVGPIGNFSSYSSFSKIVFSFCMLAGRLEIYPMLVMLSPSRMRK
I

Sequences:

>Translated_481_residues
MNYPIVFKVLGDVIKYEALVMIFPLIASLYYGGKDANSFIITIAIMLCTAVIMSNIRPKNRTFYAKEGFLSVSVCWIVIS
LFGALPFYISGAIPSFVDCIFETVSGFTTTGATILTEVESLPRGILFWRSFTHWIGGMGILIFTLALMPSIGGTTIHLLK
AESPGPTPGKIVPRIKETAKIMYLIYFAMTILQISLLLIAGMEPYDALIHAFGTAGTGGFSSMNSSVGAYNNVYIEVIIT
VFMLLFGVNFNVYFQLIAGNIKQAFKNEEVKYYIGMVLIAMTIIAFNIKGMYGGSLKEGFRQSSFQVASIVTTTGYATTN
FDLWPTLSKSILALLMLTGCCAGSTGGGIKTVRIVLLFKAMKREISKIIHPRMVNSVKLDGKAVEDETISQVGLFVFAYV
SIIIIAVLLVSIDGMDMETTLSSVLATIGNIGPGFKVVGPIGNFSSYSSFSKIVFSFCMLAGRLEIYPMLVMLSPSRMRK
I
>Mature_481_residues
MNYPIVFKVLGDVIKYEALVMIFPLIASLYYGGKDANSFIITIAIMLCTAVIMSNIRPKNRTFYAKEGFLSVSVCWIVIS
LFGALPFYISGAIPSFVDCIFETVSGFTTTGATILTEVESLPRGILFWRSFTHWIGGMGILIFTLALMPSIGGTTIHLLK
AESPGPTPGKIVPRIKETAKIMYLIYFAMTILQISLLLIAGMEPYDALIHAFGTAGTGGFSSMNSSVGAYNNVYIEVIIT
VFMLLFGVNFNVYFQLIAGNIKQAFKNEEVKYYIGMVLIAMTIIAFNIKGMYGGSLKEGFRQSSFQVASIVTTTGYATTN
FDLWPTLSKSILALLMLTGCCAGSTGGGIKTVRIVLLFKAMKREISKIIHPRMVNSVKLDGKAVEDETISQVGLFVFAYV
SIIIIAVLLVSIDGMDMETTLSSVLATIGNIGPGFKVVGPIGNFSSYSSFSKIVFSFCMLAGRLEIYPMLVMLSPSRMRK
I

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=488, Percent_Identity=35.4508196721311, Blast_Score=258, Evalue=9e-70,
Organism=Escherichia coli, GI1787626, Length=481, Percent_Identity=33.0561330561331, Blast_Score=257, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52470; Mature: 52470

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPIVFKVLGDVIKYEALVMIFPLIASLYYGGKDANSFIITIAIMLCTAVIMSNIRPKN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
RTFYAKEGFLSVSVCWIVISLFGALPFYISGAIPSFVDCIFETVSGFTTTGATILTEVES
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LPRGILFWRSFTHWIGGMGILIFTLALMPSIGGTTIHLLKAESPGPTPGKIVPRIKETAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
IMYLIYFAMTILQISLLLIAGMEPYDALIHAFGTAGTGGFSSMNSSVGAYNNVYIEVIIT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHH
VFMLLFGVNFNVYFQLIAGNIKQAFKNEEVKYYIGMVLIAMTIIAFNIKGMYGGSLKEGF
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RQSSFQVASIVTTTGYATTNFDLWPTLSKSILALLMLTGCCAGSTGGGIKTVRIVLLFKA
HHCCCHHHHHEEECCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
MKREISKIIHPRMVNSVKLDGKAVEDETISQVGLFVFAYVSIIIIAVLLVSIDGMDMETT
HHHHHHHHHCHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LSSVLATIGNIGPGFKVVGPIGNFSSYSSFSKIVFSFCMLAGRLEIYPMLVMLSPSRMRK
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHEEEEECHHHHHC
I
C
>Mature Secondary Structure
MNYPIVFKVLGDVIKYEALVMIFPLIASLYYGGKDANSFIITIAIMLCTAVIMSNIRPKN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
RTFYAKEGFLSVSVCWIVISLFGALPFYISGAIPSFVDCIFETVSGFTTTGATILTEVES
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LPRGILFWRSFTHWIGGMGILIFTLALMPSIGGTTIHLLKAESPGPTPGKIVPRIKETAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
IMYLIYFAMTILQISLLLIAGMEPYDALIHAFGTAGTGGFSSMNSSVGAYNNVYIEVIIT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHH
VFMLLFGVNFNVYFQLIAGNIKQAFKNEEVKYYIGMVLIAMTIIAFNIKGMYGGSLKEGF
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RQSSFQVASIVTTTGYATTNFDLWPTLSKSILALLMLTGCCAGSTGGGIKTVRIVLLFKA
HHCCCHHHHHEEECCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
MKREISKIIHPRMVNSVKLDGKAVEDETISQVGLFVFAYVSIIIIAVLLVSIDGMDMETT
HHHHHHHHHCHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LSSVLATIGNIGPGFKVVGPIGNFSSYSSFSKIVFSFCMLAGRLEIYPMLVMLSPSRMRK
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHEEEEECHHHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]