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The map label for this gene is aroB

Identifier: 170756308

GI number: 170756308

Start: 1633235

End: 1634323

Strand: Direct

Name: aroB

Synonym: CLD_3080

Alternate gene names: 170756308

Gene position: 1633235-1634323 (Clockwise)

Preceding gene: 170755812

Following gene: 170757343

Centisome position: 41.26

GC content: 25.62

Gene sequence:

>1089_bases
ATGAAAGAAATAATATTAGAAAGTTTAGAACTTAAACATAGGGTATACATAAATAATAACTTAAATAGATTTCACAATAT
ACTTTTAGAAAATAGGATAAAGGATAGCGATAGTATATTTATAATAACAGACGAAAATGTATATAACTTATATAAACATA
AAATGGAACAGTTTATAAATAAAAATAAGTATTTTGTATTTGTCATGGAACCAGGGGAAGAAAATAAAAATATTAATACA
ATAAATAAAATATATGATTTTTTAATGGATAATAATGCTAATAGACATAGTGTATTAATAGCTTTTGGTGGAGGAATAGT
AGGAGATATTACAGGATTTGTAGCATCTACATATATGAGGGGGTTACGTTTTATAAATATACCTACTACCCTATTAGCTC
AAGTAGACAGCTCAATAGGAGGAAAAGTAGGATATAACCATAGAGAAATAAAAAACTTAATAGGTAATTTTTACAATCCA
GTCTTTGTTTATGTTAGTACTAGTTTTTTAAAAACTTTAAGTAAAAGGGAGTTTTTAAATGGATTAGGAGAAATAATAAA
ATATTCTTTAATAAGGGAGAATGATTTAGCTTATTTTATAGAAAAGAATATTAAATTTATATTAGAAAGAGAGCAAGATA
AGCTTATTCATATAGTGAAGGAATGTTTATCTATAAAAGCAGCTATTGTAGAAGAAGACTTTAGGGATTTAGGTATGAGG
AATTCCTTAAATTTTGGTCATACCGTAGGGCATGCAATAGAAGCTAATTCTAGTTACAGGATATCTCATGGAGAAGCAGT
GGCTTTAGGTATACTAGTAGCCTTAAAATTGTCAGAAAAAAAGCTAAATCTAGATAAAAACATATATAATAATGTGGTAC
AGTTATATAAAAAGTTAAATTTACCACTTTTCTATAAAGTTGACAACTATAAAACATTTTTGTATGCTATAAGACATGAT
AAAAAAAATAGAGAAAAAATTAGATTTGCTTTACTAGAGAAAGTAGGTAAAGTAAAGGTAAAAGTAGAAGTAGAAGAAAA
TGAGATTATTAAAGCTATAAAAGAAAGTATAGATAGGGAGGAAAAATAA

Upstream 100 bases:

>100_bases
ATTTTTATAGGTTATTCTAAAGTTTCATAGAGAAGCATTTGTTATAATAGCAATTTACAATGATTTCAGAATTACTTTAT
ATATGAAAGTAGGTGAATTT

Downstream 100 bases:

>100_bases
ATGACAATAGGTATTATAGGTGCAATGGATGAGGAATTAGAATTATTATTAAAGGAATTAGATTTGGAAAAAAAACAAGT
TAAAGCCAATATGACATTTA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFINKNKYFVFVMEPGEENKNINT
INKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMRGLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNP
VFVYVSTSFLKTLSKREFLNGLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLNLPLFYKVDNYKTFLYAIRHD
KKNREKIRFALLEKVGKVKVKVEVEENEIIKAIKESIDREEK

Sequences:

>Translated_362_residues
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFINKNKYFVFVMEPGEENKNINT
INKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMRGLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNP
VFVYVSTSFLKTLSKREFLNGLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLNLPLFYKVDNYKTFLYAIRHD
KKNREKIRFALLEKVGKVKVKVEVEENEIIKAIKESIDREEK
>Mature_362_residues
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFINKNKYFVFVMEPGEENKNINT
INKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMRGLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNP
VFVYVSTSFLKTLSKREFLNGLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLNLPLFYKVDNYKTFLYAIRHD
KKNREKIRFALLEKVGKVKVKVEVEENEIIKAIKESIDREEK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=329, Percent_Identity=35.258358662614, Blast_Score=210, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6320332, Length=360, Percent_Identity=33.0555555555556, Blast_Score=179, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 42053; Mature: 42053

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFIN
CHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHC
KNKYFVFVMEPGEENKNINTINKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
GLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNPVFVYVSTSFLKTLSKREFLN
CCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHH
GLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
HHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLN
CCCCCCCHHCCEEECCCCEEECCCCHHHHHHHHHHEECCHHCCCCHHHHHHHHHHHHHCC
LPLFYKVDNYKTFLYAIRHDKKNREKIRFALLEKVGKVKVKVEVEENEIIKAIKESIDRE
CCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHCCC
EK
CC
>Mature Secondary Structure
MKEIILESLELKHRVYINNNLNRFHNILLENRIKDSDSIFIITDENVYNLYKHKMEQFIN
CHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHC
KNKYFVFVMEPGEENKNINTINKIYDFLMDNNANRHSVLIAFGGGIVGDITGFVASTYMR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
GLRFINIPTTLLAQVDSSIGGKVGYNHREIKNLIGNFYNPVFVYVSTSFLKTLSKREFLN
CCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHH
GLGEIIKYSLIRENDLAYFIEKNIKFILEREQDKLIHIVKECLSIKAAIVEEDFRDLGMR
HHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSLNFGHTVGHAIEANSSYRISHGEAVALGILVALKLSEKKLNLDKNIYNNVVQLYKKLN
CCCCCCCHHCCEEECCCCEEECCCCHHHHHHHHHHEECCHHCCCCHHHHHHHHHHHHHCC
LPLFYKVDNYKTFLYAIRHDKKNREKIRFALLEKVGKVKVKVEVEENEIIKAIKESIDRE
CCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHCCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]