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The map label for this gene is pgcA [H]

Identifier: 170756131

GI number: 170756131

Start: 3932029

End: 3933750

Strand: Reverse

Name: pgcA [H]

Synonym: CLD_0855

Alternate gene names: 170756131

Gene position: 3933750-3932029 (Counterclockwise)

Preceding gene: 170756938

Following gene: 170755260

Centisome position: 99.38

GC content: 29.21

Gene sequence:

>1722_bases
ATGGATTACAAAAAAGTATATAAAGAATGGTTAGATAATGATTATATTGATGAAGATATAAAAAAAGAATTAAAGGAGAT
AATAAATAATGAAAAGGAAATAGAAGATAGATTTTATAAAGAATTAGAATTTGGAACTGCAGGCCTTAGAGGAAAAATCG
GAGCAGGTACAAATAGAATGAATATATACAATATATCTAAGGTTACTCAGGGATTAGCAGATTATATAACAGAAAAAGGT
GAAGAATATATAAATAGGGGTGTTGCTATAGCTTTTGATTGCAGACATTATTCAAAAGAATTTGCTAAAACTGCAGCCTT
AGTTTTGGCTGGTAATGGAATAAAGAGTTATTTATTTGAAGATTTAAGACCAACGCCAGAATTATCTTTTGCAGTTAGAA
AATTGAATACGGCTGCAGGTATAGTTATAACTGCAAGTCATAATCCAAAGGATTATAATGGTTATAAAGTATATTGGGAA
GATGGTGCTCAAGTTTTAACTCAAATAGCAAATGGTATTACTGAGAAAATAAAATCTATTGGTAAATTTAGTGATATAAA
AACTATGAGTGAGGAAAAAGCTTTAAAAAGTGGGTTATTAAATATATTAGGAGAAGATATAGATTTTGAATATATAGAAA
GGGTTAAATCTTTAAGTATAAGAGAAGATATCGATAAGGATATAAAAGTTATTTATACACCTTTAAATGGAACAGGAAAT
ATTCCTGTTAGACGTGTTTTAAGAGAAAGAGGGTTTACTAACATTATAGTAGTTCCAGAGCAGGAAAACCCTGATCCAGA
CTTTACAACAGTAGGATATCCAAATCCAGAGGATACAAAAGCATTTAGATATGCAGAAAACTTAGGAAAAAAAGTAGATG
CAGAATTACTTATAGCAACAGATCCAGATTGTGATAGATTAGCTATAGAGGTTAAAGATAAAAATGGTGAGTATTTAGCC
TTTAATGGTAATCAAACAGGAGCTATTCTTATAAATTATATAGTATCAAATATGAAAGAGATGGGTAAATTACCTAAGGG
TGCTGCTATAGTTAAATCCATAGTTACTGGGGATTTAGGTAAAGTTATTGGAGAAGAATACGGAGTAGAAACCTATGAAG
CATTAACTGGATTTAAAAACATATGTGGTAAAATACCTAATTTAAAAGAAGAAGGTAAAGAATTTATATTCGGATATGAA
GAAAGTATAGGGTATGTTACAGGTACATTTGTTAGAGATAAAGATGGAGTAAGTTCAAGTATGCTTTTATGTGAGGCAGC
AGCTTATTATAAAACTAAGGGTAAAACATTAATAGATGTACTTAATGAAATATATGAAAAGCATGGATATTATAGAGAAA
AGCAAATATCACTAATATTAGAAGGGATAGAGGGTAAAAAGAGAATAGATAGAATGATGGAATCATATAGGAAAAGTTTC
CCGAAGGAAATAGCAGGAGCAAAGCTTTTAACTTATATAGATTATCAGGATAGAATAGAATACGATATTATAAAAAATGA
TAGAAAGCCATGTAGAATACCTAGATCAAATGTATTAAGATTCTTTTTAGATGATGGCAGTTGGTATGCAGTAAGGCCAT
CAGGTACAGAACCTAAAATAAAATTATATGTATATACAAAAGGTAAAAGTATTAAAGCTGCTGAAGAAAAAATAAAAGCT
ATAGAAAAGGAAGTTTTAGATAAACTTAATTCAGTAAAATAG

Upstream 100 bases:

>100_bases
GAGTATATAAAATAATATTATTTAAGAAGGAAATACATAAAAAATATTGAAATTAATAATTAATGGAATAAAAGCTTTCA
GTTAAGAGGAGAGATAATAT

Downstream 100 bases:

>100_bases
ATTAATTTAATAAAATTTTATATAATAGTAAGATATTTTAATATTATGATATGTGTTTTTGATTAAAAATAAAGAAAAGA
TTATTTTATAGAAATAATAA

Product: phosphoglucomutase/phosphomannomutase family protein

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MDYKKVYKEWLDNDYIDEDIKKELKEIINNEKEIEDRFYKELEFGTAGLRGKIGAGTNRMNIYNISKVTQGLADYITEKG
EEYINRGVAIAFDCRHYSKEFAKTAALVLAGNGIKSYLFEDLRPTPELSFAVRKLNTAAGIVITASHNPKDYNGYKVYWE
DGAQVLTQIANGITEKIKSIGKFSDIKTMSEEKALKSGLLNILGEDIDFEYIERVKSLSIREDIDKDIKVIYTPLNGTGN
IPVRRVLRERGFTNIIVVPEQENPDPDFTTVGYPNPEDTKAFRYAENLGKKVDAELLIATDPDCDRLAIEVKDKNGEYLA
FNGNQTGAILINYIVSNMKEMGKLPKGAAIVKSIVTGDLGKVIGEEYGVETYEALTGFKNICGKIPNLKEEGKEFIFGYE
ESIGYVTGTFVRDKDGVSSSMLLCEAAAYYKTKGKTLIDVLNEIYEKHGYYREKQISLILEGIEGKKRIDRMMESYRKSF
PKEIAGAKLLTYIDYQDRIEYDIIKNDRKPCRIPRSNVLRFFLDDGSWYAVRPSGTEPKIKLYVYTKGKSIKAAEEKIKA
IEKEVLDKLNSVK

Sequences:

>Translated_573_residues
MDYKKVYKEWLDNDYIDEDIKKELKEIINNEKEIEDRFYKELEFGTAGLRGKIGAGTNRMNIYNISKVTQGLADYITEKG
EEYINRGVAIAFDCRHYSKEFAKTAALVLAGNGIKSYLFEDLRPTPELSFAVRKLNTAAGIVITASHNPKDYNGYKVYWE
DGAQVLTQIANGITEKIKSIGKFSDIKTMSEEKALKSGLLNILGEDIDFEYIERVKSLSIREDIDKDIKVIYTPLNGTGN
IPVRRVLRERGFTNIIVVPEQENPDPDFTTVGYPNPEDTKAFRYAENLGKKVDAELLIATDPDCDRLAIEVKDKNGEYLA
FNGNQTGAILINYIVSNMKEMGKLPKGAAIVKSIVTGDLGKVIGEEYGVETYEALTGFKNICGKIPNLKEEGKEFIFGYE
ESIGYVTGTFVRDKDGVSSSMLLCEAAAYYKTKGKTLIDVLNEIYEKHGYYREKQISLILEGIEGKKRIDRMMESYRKSF
PKEIAGAKLLTYIDYQDRIEYDIIKNDRKPCRIPRSNVLRFFLDDGSWYAVRPSGTEPKIKLYVYTKGKSIKAAEEKIKA
IEKEVLDKLNSVK
>Mature_573_residues
MDYKKVYKEWLDNDYIDEDIKKELKEIINNEKEIEDRFYKELEFGTAGLRGKIGAGTNRMNIYNISKVTQGLADYITEKG
EEYINRGVAIAFDCRHYSKEFAKTAALVLAGNGIKSYLFEDLRPTPELSFAVRKLNTAAGIVITASHNPKDYNGYKVYWE
DGAQVLTQIANGITEKIKSIGKFSDIKTMSEEKALKSGLLNILGEDIDFEYIERVKSLSIREDIDKDIKVIYTPLNGTGN
IPVRRVLRERGFTNIIVVPEQENPDPDFTTVGYPNPEDTKAFRYAENLGKKVDAELLIATDPDCDRLAIEVKDKNGEYLA
FNGNQTGAILINYIVSNMKEMGKLPKGAAIVKSIVTGDLGKVIGEEYGVETYEALTGFKNICGKIPNLKEEGKEFIFGYE
ESIGYVTGTFVRDKDGVSSSMLLCEAAAYYKTKGKTLIDVLNEIYEKHGYYREKQISLILEGIEGKKRIDRMMESYRKSF
PKEIAGAKLLTYIDYQDRIEYDIIKNDRKPCRIPRSNVLRFFLDDGSWYAVRPSGTEPKIKLYVYTKGKSIKAAEEKIKA
IEKEVLDKLNSVK

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=561, Percent_Identity=33.8680926916221, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI31377548, Length=585, Percent_Identity=33.1623931623932, Blast_Score=278, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI71993870, Length=589, Percent_Identity=33.616298811545, Blast_Score=282, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI71993878, Length=321, Percent_Identity=34.8909657320872, Blast_Score=171, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6323934, Length=550, Percent_Identity=32.9090909090909, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI20129809, Length=534, Percent_Identity=30.7116104868914, Blast_Score=252, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24651977, Length=429, Percent_Identity=33.1002331002331, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24653722, Length=466, Percent_Identity=32.8326180257511, Blast_Score=212, Evalue=6e-55,
Organism=Drosophila melanogaster, GI17864244, Length=549, Percent_Identity=23.6794171220401, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 64959; Mature: 64959

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKKVYKEWLDNDYIDEDIKKELKEIINNEKEIEDRFYKELEFGTAGLRGKIGAGTNRM
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
NIYNISKVTQGLADYITEKGEEYINRGVAIAFDCRHYSKEFAKTAALVLAGNGIKSYLFE
EEEEHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHHEEECCCHHHHHHH
DLRPTPELSFAVRKLNTAAGIVITASHNPKDYNGYKVYWEDGAQVLTQIANGITEKIKSI
HCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
GKFSDIKTMSEEKALKSGLLNILGEDIDFEYIERVKSLSIREDIDKDIKVIYTPLNGTGN
HCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
IPVRRVLRERGFTNIIVVPEQENPDPDFTTVGYPNPEDTKAFRYAENLGKKVDAELLIAT
CHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEC
DPDCDRLAIEVKDKNGEYLAFNGNQTGAILINYIVSNMKEMGKLPKGAAIVKSIVTGDLG
CCCCCEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KVIGEEYGVETYEALTGFKNICGKIPNLKEEGKEFIFGYEESIGYVTGTFVRDKDGVSSS
HHHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCHHEEEEHHHCCCCEEEEEEECCCCCCHH
MLLCEAAAYYKTKGKTLIDVLNEIYEKHGYYREKQISLILEGIEGKKRIDRMMESYRKSF
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
PKEIAGAKLLTYIDYQDRIEYDIIKNDRKPCRIPRSNVLRFFLDDGSWYAVRPSGTEPKI
CHHHCCCCEEEEECHHHCCEEHHHCCCCCCCCCCHHHEEEEEEECCCEEEECCCCCCCEE
KLYVYTKGKSIKAAEEKIKAIEKEVLDKLNSVK
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYKKVYKEWLDNDYIDEDIKKELKEIINNEKEIEDRFYKELEFGTAGLRGKIGAGTNRM
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
NIYNISKVTQGLADYITEKGEEYINRGVAIAFDCRHYSKEFAKTAALVLAGNGIKSYLFE
EEEEHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHHEEECCCHHHHHHH
DLRPTPELSFAVRKLNTAAGIVITASHNPKDYNGYKVYWEDGAQVLTQIANGITEKIKSI
HCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
GKFSDIKTMSEEKALKSGLLNILGEDIDFEYIERVKSLSIREDIDKDIKVIYTPLNGTGN
HCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
IPVRRVLRERGFTNIIVVPEQENPDPDFTTVGYPNPEDTKAFRYAENLGKKVDAELLIAT
CHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEC
DPDCDRLAIEVKDKNGEYLAFNGNQTGAILINYIVSNMKEMGKLPKGAAIVKSIVTGDLG
CCCCCEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KVIGEEYGVETYEALTGFKNICGKIPNLKEEGKEFIFGYEESIGYVTGTFVRDKDGVSSS
HHHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCHHEEEEHHHCCCCEEEEEEECCCCCCHH
MLLCEAAAYYKTKGKTLIDVLNEIYEKHGYYREKQISLILEGIEGKKRIDRMMESYRKSF
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
PKEIAGAKLLTYIDYQDRIEYDIIKNDRKPCRIPRSNVLRFFLDDGSWYAVRPSGTEPKI
CHHHCCCCEEEEECHHHCCEEHHHCCCCCCCCCCHHHEEEEEEECCCEEEECCCCCCCEE
KLYVYTKGKSIKAAEEKIKAIEKEVLDKLNSVK
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]