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The map label for this gene is tlpC [H]

Identifier: 170756049

GI number: 170756049

Start: 849669

End: 851135

Strand: Direct

Name: tlpC [H]

Synonym: CLD_0034

Alternate gene names: 170756049

Gene position: 849669-851135 (Clockwise)

Preceding gene: 170754982

Following gene: 170755488

Centisome position: 21.47

GC content: 28.22

Gene sequence:

>1467_bases
ATGGATTACAAAAAAAACGTGGAATTGAAGAATAAAATTATGTTGGCAGGATTTATAGCATCCGTAGTATTAAGAGCAAT
TTTTGATATAATTTTAAAGGTAGATAGGAATGCCATATTAATATTAGTTGGACTTTCCATACCTTTAGCTGTAATAGATT
TTATATTAATAAAAAAGAAATTCATTATTCAAACAATGTATTATACGGTAATGATGTACATTGCTGTTATATGTATAATG
TTTATATCAGACCCAAATTGGGCTAATTTTATTTTGATATATTATGGTGTTATATTAATGAGTGTATATCAAGATTTAAT
GATATTAATTATTGAAGCAATTTTGGCTACAGTACTTGTAGTGTATTTCTTCTTAGGCTATAAAACAACACTCTTTGCTT
CCGTAGGATACTATGAATTAGTATTTTATATAGCATACATAGTAGCAGGAACGGCTATATTATCGATTAATGCCATTACT
ACCAAAAGTATTTATAAAGATTTAGAAGAAACTCATAAAGCTACTGAAGAAGCTAAATCTAGAGCAGAGTTGTTGCTAGA
AAAAATATATAGTACTATAAAAGTTTTAACAGCAACTAATGAGAAAATAAAAAGTGGAATTTCTGTAGCAGGACAAATAG
CAGAAGAAATAACTAGCTCTACAAGCGATGTTGCTAATAGTGCAACCAAAGAAGTTGATGTAATGATTGGAATGAAAGCC
TCAATAGAGGGTGGAGTAGAAAAAGTAGAAGAAGTTACGAATGCTATTAAAACTATGGAGGAATCATCCAAGTCAACTGA
AAATGTTGTATTAGAAGGTAATAATAAAGTAGATATATTATCTTCGGAAATGAATAAGGTAAATACAAATATTTTAAGTG
TGGTATCCATGATAAATGAATTAAGTGATGAAAATACAAAAATAGTTCATATTATTAGCAGTATTACAAAAATATCAGAG
CAAACCAATCTATTAGCCCTTAATGCATCAATAGAAGCAGCTAGAGCTGGAGAGTATGGAAAAAGTTTTGCTGTAGTTGC
AGAAGAAGTAAGAAAACTTGCTGAGGATTCGAAAGAATCTACAGATCAAATAGAATTAATATTGAATAATATATCTAATA
AAACAAAGGTAGTTGCAGAAGAAATATTAAAAGAAGAAAAGTCAATCGAATTATGTAATGAGCATACAAATGATGTTAAA
GAGTTATTTAAAGATGTTAATAAGAATACTTCTAATGTATTAAGTTATTCAAGCAGTGTTGGATCACAATCTATATTGCT
TGAAAGTACGATGAAAAATACATTAAGTTCAGTAAATAATATTAGCGAAACTGTAGAATCCACTGCAACTGCTATGGAAG
AAATTTTTACGGCTATTGATGAGCTTAATAATAGCATAATTGGTATAACAAGTAGTTATGATGAAATAGATGATATATGT
AATGAATTAAACTCTATAAGTGAATAA

Upstream 100 bases:

>100_bases
ATAAATTAAGAAAATTATGCAGAAAAATGTTGAATGTGGTAAAGTTGTGTAGTGATATTACGAATAATAATAATGGTATA
TTGACCAAGGGGGTGTAGTA

Downstream 100 bases:

>100_bases
AATAGATAATATAAAAAGATGGTTATTGCAAATTAGCAGTGACCATCTTTTTTGTATAGCATAGTTATAAAGGATAATGT
TAAAAGATAAGACTAATGGA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MDYKKNVELKNKIMLAGFIASVVLRAIFDIILKVDRNAILILVGLSIPLAVIDFILIKKKFIIQTMYYTVMMYIAVICIM
FISDPNWANFILIYYGVILMSVYQDLMILIIEAILATVLVVYFFLGYKTTLFASVGYYELVFYIAYIVAGTAILSINAIT
TKSIYKDLEETHKATEEAKSRAELLLEKIYSTIKVLTATNEKIKSGISVAGQIAEEITSSTSDVANSATKEVDVMIGMKA
SIEGGVEKVEEVTNAIKTMEESSKSTENVVLEGNNKVDILSSEMNKVNTNILSVVSMINELSDENTKIVHIISSITKISE
QTNLLALNASIEAARAGEYGKSFAVVAEEVRKLAEDSKESTDQIELILNNISNKTKVVAEEILKEEKSIELCNEHTNDVK
ELFKDVNKNTSNVLSYSSSVGSQSILLESTMKNTLSSVNNISETVESTATAMEEIFTAIDELNNSIIGITSSYDEIDDIC
NELNSISE

Sequences:

>Translated_488_residues
MDYKKNVELKNKIMLAGFIASVVLRAIFDIILKVDRNAILILVGLSIPLAVIDFILIKKKFIIQTMYYTVMMYIAVICIM
FISDPNWANFILIYYGVILMSVYQDLMILIIEAILATVLVVYFFLGYKTTLFASVGYYELVFYIAYIVAGTAILSINAIT
TKSIYKDLEETHKATEEAKSRAELLLEKIYSTIKVLTATNEKIKSGISVAGQIAEEITSSTSDVANSATKEVDVMIGMKA
SIEGGVEKVEEVTNAIKTMEESSKSTENVVLEGNNKVDILSSEMNKVNTNILSVVSMINELSDENTKIVHIISSITKISE
QTNLLALNASIEAARAGEYGKSFAVVAEEVRKLAEDSKESTDQIELILNNISNKTKVVAEEILKEEKSIELCNEHTNDVK
ELFKDVNKNTSNVLSYSSSVGSQSILLESTMKNTLSSVNNISETVESTATAMEEIFTAIDELNNSIIGITSSYDEIDDIC
NELNSISE
>Mature_488_residues
MDYKKNVELKNKIMLAGFIASVVLRAIFDIILKVDRNAILILVGLSIPLAVIDFILIKKKFIIQTMYYTVMMYIAVICIM
FISDPNWANFILIYYGVILMSVYQDLMILIIEAILATVLVVYFFLGYKTTLFASVGYYELVFYIAYIVAGTAILSINAIT
TKSIYKDLEETHKATEEAKSRAELLLEKIYSTIKVLTATNEKIKSGISVAGQIAEEITSSTSDVANSATKEVDVMIGMKA
SIEGGVEKVEEVTNAIKTMEESSKSTENVVLEGNNKVDILSSEMNKVNTNILSVVSMINELSDENTKIVHIISSITKISE
QTNLLALNASIEAARAGEYGKSFAVVAEEVRKLAEDSKESTDQIELILNNISNKTKVVAEEILKEEKSIELCNEHTNDVK
ELFKDVNKNTSNVLSYSSSVGSQSILLESTMKNTLSSVNNISETVESTATAMEEIFTAIDELNNSIIGITSSYDEIDDIC
NELNSISE

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=265, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788195, Length=193, Percent_Identity=29.5336787564767, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789453, Length=118, Percent_Identity=34.7457627118644, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787690, Length=283, Percent_Identity=26.8551236749117, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788194, Length=167, Percent_Identity=30.5389221556886, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 53916; Mature: 53916

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKKNVELKNKIMLAGFIASVVLRAIFDIILKVDRNAILILVGLSIPLAVIDFILIKKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHH
FIIQTMYYTVMMYIAVICIMFISDPNWANFILIYYGVILMSVYQDLMILIIEAILATVLV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYFFLGYKTTLFASVGYYELVFYIAYIVAGTAILSINAITTKSIYKDLEETHKATEEAKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
RAELLLEKIYSTIKVLTATNEKIKSGISVAGQIAEEITSSTSDVANSATKEVDVMIGMKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCHH
SIEGGVEKVEEVTNAIKTMEESSKSTENVVLEGNNKVDILSSEMNKVNTNILSVVSMINE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
LSDENTKIVHIISSITKISEQTNLLALNASIEAARAGEYGKSFAVVAEEVRKLAEDSKES
HCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
TDQIELILNNISNKTKVVAEEILKEEKSIELCNEHTNDVKELFKDVNKNTSNVLSYSSSV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCC
GSQSILLESTMKNTLSSVNNISETVESTATAMEEIFTAIDELNNSIIGITSSYDEIDDIC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHH
NELNSISE
HHHHCCCC
>Mature Secondary Structure
MDYKKNVELKNKIMLAGFIASVVLRAIFDIILKVDRNAILILVGLSIPLAVIDFILIKKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHH
FIIQTMYYTVMMYIAVICIMFISDPNWANFILIYYGVILMSVYQDLMILIIEAILATVLV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYFFLGYKTTLFASVGYYELVFYIAYIVAGTAILSINAITTKSIYKDLEETHKATEEAKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
RAELLLEKIYSTIKVLTATNEKIKSGISVAGQIAEEITSSTSDVANSATKEVDVMIGMKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCHH
SIEGGVEKVEEVTNAIKTMEESSKSTENVVLEGNNKVDILSSEMNKVNTNILSVVSMINE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
LSDENTKIVHIISSITKISEQTNLLALNASIEAARAGEYGKSFAVVAEEVRKLAEDSKES
HCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
TDQIELILNNISNKTKVVAEEILKEEKSIELCNEHTNDVKELFKDVNKNTSNVLSYSSSV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCC
GSQSILLESTMKNTLSSVNNISETVESTATAMEEIFTAIDELNNSIIGITSSYDEIDDIC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHH
NELNSISE
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]