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The map label for this gene is nirC [H]

Identifier: 170756005

GI number: 170756005

Start: 1067976

End: 1068752

Strand: Direct

Name: nirC [H]

Synonym: CLD_3604

Alternate gene names: 170756005

Gene position: 1067976-1068752 (Clockwise)

Preceding gene: 170756563

Following gene: 170754948

Centisome position: 26.98

GC content: 32.05

Gene sequence:

>777_bases
ATGTATAGTGAAGAAATTAACAAGATTAGTAATGTAGCAGAAAACAAAAGGGACTTATTAAGAAATAATAGAGTAGGCTA
TTTAATATCTTCTGCTCTTGCGGGAATATATGTAGGCATAGGTACTATACTCATATTTACACTAGGCGGAAATTTAGAAT
CTGTTAATTCTTCTTATGTAAAGCTTATCATGGGTTTATCTTTCGGCATAGCTTTAAGTCTTGTTATTATGGCTGGATCA
GAACTTTTTACAGGAAATAATATGGTTATGGCCATAGGAACATTAAATAAGAAAACTACATGGAAGGATGCCTTAAGCAT
ATGGGGGAATAGCTTTGCAGGAAATTTAATAGGATCAATGCTTTTAGCTTTAATATTTGTTAATACAGGATTAGCAAAAG
GATCTGTAGGTAAATTTATTTTAAAAACAGCAGAAACAAAGATGACGTTACAACCTATGGAATTATTTTTAAGAGGTTTG
CTGTGCAATATTTTAGTCTGTTTAGCTGTATGGTGTAGCTTAAAGATGAAAGAAGAGGCAGGAAAACTCATAATGATATT
TTGGTGCTTATTTGCCTTTATATCATCAGGATTTGAACACAGTGTGGCAAATATGACTTTGCTTTCTATAGCTTTATTTA
TACCACATGGAGTTGGAATATCTGTAAATGGAATGGCATACAATTTAATTTTTGTTACTTTGGGAAACATTATAGGCGGA
GCATTATTTGTGGGAGCAGCCTATTATAAGATATCAGAAAATAGTTTTAAGAGGTGA

Upstream 100 bases:

>100_bases
AGAGTATGTGATTTTCATCACATACTTTTTTTTGTATGCACTATAGAATAGAGTATAAGAAATAATGGAGTTATTAAAAA
AAGAAAGGAGATGTTGGATC

Downstream 100 bases:

>100_bases
AATATGATGGGTTTTAAGATTAGAAAAGAAAATTTTAATAATGCTTTAAAAAATTTAAGAAAAGATTTTAAAGTTTACGC
ACCAGCCACATTAGAAGGGA

Product: formate/nitrite transporter family protein

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MYSEEINKISNVAENKRDLLRNNRVGYLISSALAGIYVGIGTILIFTLGGNLESVNSSYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSMLLALIFVNTGLAKGSVGKFILKTAETKMTLQPMELFLRGL
LCNILVCLAVWCSLKMKEEAGKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGVGISVNGMAYNLIFVTLGNIIGG
ALFVGAAYYKISENSFKR

Sequences:

>Translated_258_residues
MYSEEINKISNVAENKRDLLRNNRVGYLISSALAGIYVGIGTILIFTLGGNLESVNSSYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSMLLALIFVNTGLAKGSVGKFILKTAETKMTLQPMELFLRGL
LCNILVCLAVWCSLKMKEEAGKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGVGISVNGMAYNLIFVTLGNIIGG
ALFVGAAYYKISENSFKR
>Mature_258_residues
MYSEEINKISNVAENKRDLLRNNRVGYLISSALAGIYVGIGTILIFTLGGNLESVNSSYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSMLLALIFVNTGLAKGSVGKFILKTAETKMTLQPMELFLRGL
LCNILVCLAVWCSLKMKEEAGKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGVGISVNGMAYNLIFVTLGNIIGG
ALFVGAAYYKISENSFKR

Specific function: May act as a nitrite transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=256, Percent_Identity=43.359375, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1787132, Length=238, Percent_Identity=31.0924369747899, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788837, Length=264, Percent_Identity=28.4090909090909, Blast_Score=81, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321779, Length=225, Percent_Identity=31.1111111111111, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 27912; Mature: 27912

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSEEINKISNVAENKRDLLRNNRVGYLISSALAGIYVGIGTILIFTLGGNLESVNSSYV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KLIMGLSFGIALSLVIMAGSELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSM
HHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHH
LLALIFVNTGLAKGSVGKFILKTAETKMTLQPMELFLRGLLCNILVCLAVWCSLKMKEEA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
GKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGVGISVNGMAYNLIFVTLGNIIGG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
ALFVGAAYYKISENSFKR
HHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MYSEEINKISNVAENKRDLLRNNRVGYLISSALAGIYVGIGTILIFTLGGNLESVNSSYV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KLIMGLSFGIALSLVIMAGSELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSM
HHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHH
LLALIFVNTGLAKGSVGKFILKTAETKMTLQPMELFLRGLLCNILVCLAVWCSLKMKEEA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
GKLIMIFWCLFAFISSGFEHSVANMTLLSIALFIPHGVGISVNGMAYNLIFVTLGNIIGG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
ALFVGAAYYKISENSFKR
HHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1987123; 11677609 [H]