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The map label for this gene is trxB

Identifier: 170755998

GI number: 170755998

Start: 1390715

End: 1391656

Strand: Direct

Name: trxB

Synonym: CLD_3308

Alternate gene names: 170755998

Gene position: 1390715-1391656 (Clockwise)

Preceding gene: 170754908

Following gene: 170754951

Centisome position: 35.13

GC content: 32.48

Gene sequence:

>942_bases
ATGGAAAATCTTTATGATGTTATAATCATAGGTTCTGGTCCAGCAGGATTATCAGCAGGTTTATATGCTGCAAGAGCTAG
ATTAAAAACTTTAATATTAGAGAGAAATAAAGCAGGTGGACAGATAGTAATAACAGATGAAGTGGCTAACTATCCAGGAT
CTATAAGAGATGCTACAGGAGCAAGTTTAGTAGCTAGAATGGAAGAACAAGTGGATGAATTTGGAGCGGAAAGAAAAAAA
GATAATGTTAAAGAGGTAGATTTTACTGGCAAAATAAAAATTATAAAGGGAGAAAAGGAAGAGTATAAAGCAAAATCTGT
AATTATAGCTACTGGTGCTGCTCCTAGGCATATAGGTTGCAAAGGTGAAAATGAATTAATAGGAAAGGGAGTATCCTATT
GTGCTACGTGTGATGCTGACTTTTTTACAGATTTAGAAGTGTTCGTAATAGGTGGAGGAGATTCAGCTTTAGAAGAAGCT
TTATATCTTACTAAGTTTGCAAGAAAGGTAACAGTAGTTCATAGAAGAGATGCCCTAAGAGGAGCTAAATCAATACAAGA
AAAAGTGTTTAAAAATCCTAAAATAGAAATTATGTGGGATTCTGTAGTAGAAGAAATAAAAGGCGATGGAATAGTAGAAT
CTGCAGTATTTAAAAATAAAAAAACAGGAGAAATAACTGAATACTTTGCAGATGAAGATGATGGAACTTTTGGAATATTT
GTTTTTGTAGGATATTTACCTATAAACAATTTATTTAAAGATATTGTTATTATGAATGAAGCAGGATATATAAAAACTAA
CGATAGAATGGAAACAAATATAGAGGGTATATTTGCTGCCGGTGATATAAGAGAAAAATCATTAAGACAGGTAGTTACTG
CAGCTGCAGATGGTGCTATAGCAGCAGTAGAAGCTTATAAATATGTTGAAGATACTTTTTAA

Upstream 100 bases:

>100_bases
AATAGTTTCACGTGTTAATTTTATTTAAACAATTGAATTGATAAAAATATAATTTAATAAATATAAACATCTGAATATTA
AATTATAGGGGGGATAAGAT

Downstream 100 bases:

>100_bases
ATATAAAAAATTTATTTGAAAGGCGGTTATAAAATGTTAGTAATTGATAAGAAAACTTTTGAAGACGAGGTATTAAAATC
AGATGGTTATACGTTAGTAG

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MENLYDVIIIGSGPAGLSAGLYAARARLKTLILERNKAGGQIVITDEVANYPGSIRDATGASLVARMEEQVDEFGAERKK
DNVKEVDFTGKIKIIKGEKEEYKAKSVIIATGAAPRHIGCKGENELIGKGVSYCATCDADFFTDLEVFVIGGGDSALEEA
LYLTKFARKVTVVHRRDALRGAKSIQEKVFKNPKIEIMWDSVVEEIKGDGIVESAVFKNKKTGEITEYFADEDDGTFGIF
VFVGYLPINNLFKDIVIMNEAGYIKTNDRMETNIEGIFAAGDIREKSLRQVVTAAADGAIAAVEAYKYVEDTF

Sequences:

>Translated_313_residues
MENLYDVIIIGSGPAGLSAGLYAARARLKTLILERNKAGGQIVITDEVANYPGSIRDATGASLVARMEEQVDEFGAERKK
DNVKEVDFTGKIKIIKGEKEEYKAKSVIIATGAAPRHIGCKGENELIGKGVSYCATCDADFFTDLEVFVIGGGDSALEEA
LYLTKFARKVTVVHRRDALRGAKSIQEKVFKNPKIEIMWDSVVEEIKGDGIVESAVFKNKKTGEITEYFADEDDGTFGIF
VFVGYLPINNLFKDIVIMNEAGYIKTNDRMETNIEGIFAAGDIREKSLRQVVTAAADGAIAAVEAYKYVEDTF
>Mature_313_residues
MENLYDVIIIGSGPAGLSAGLYAARARLKTLILERNKAGGQIVITDEVANYPGSIRDATGASLVARMEEQVDEFGAERKK
DNVKEVDFTGKIKIIKGEKEEYKAKSVIIATGAAPRHIGCKGENELIGKGVSYCATCDADFFTDLEVFVIGGGDSALEEA
LYLTKFARKVTVVHRRDALRGAKSIQEKVFKNPKIEIMWDSVVEEIKGDGIVESAVFKNKKTGEITEYFADEDDGTFGIF
VFVGYLPINNLFKDIVIMNEAGYIKTNDRMETNIEGIFAAGDIREKSLRQVVTAAADGAIAAVEAYKYVEDTF

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=36.4217252396166, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87081763, Length=319, Percent_Identity=33.2288401253918, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=39.2405063291139, Blast_Score=200, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=36.1635220125786, Blast_Score=189, Evalue=7e-49,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34238; Mature: 34238

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLYDVIIIGSGPAGLSAGLYAARARLKTLILERNKAGGQIVITDEVANYPGSIRDATG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCH
ASLVARMEEQVDEFGAERKKDNVKEVDFTGKIKIIKGEKEEYKAKSVIIATGAAPRHIGC
HHHHHHHHHHHHHHCCHHCCCCCEEECCCCEEEEEECCHHHHCCEEEEEEECCCCCCCCC
KGENELIGKGVSYCATCDADFFTDLEVFVIGGGDSALEEALYLTKFARKVTVVHRRDALR
CCCCHHHHCCCCCEEECCCCHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAKSIQEKVFKNPKIEIMWDSVVEEIKGDGIVESAVFKNKKTGEITEYFADEDDGTFGIF
HHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHCCCCCCCEEEE
VFVGYLPINNLFKDIVIMNEAGYIKTNDRMETNIEGIFAAGDIREKSLRQVVTAAADGAI
EEEEHHCHHHHHHHEEEECCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHH
AAVEAYKYVEDTF
HHHHHHHHHHHCC
>Mature Secondary Structure
MENLYDVIIIGSGPAGLSAGLYAARARLKTLILERNKAGGQIVITDEVANYPGSIRDATG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCH
ASLVARMEEQVDEFGAERKKDNVKEVDFTGKIKIIKGEKEEYKAKSVIIATGAAPRHIGC
HHHHHHHHHHHHHHCCHHCCCCCEEECCCCEEEEEECCHHHHCCEEEEEEECCCCCCCCC
KGENELIGKGVSYCATCDADFFTDLEVFVIGGGDSALEEALYLTKFARKVTVVHRRDALR
CCCCHHHHCCCCCEEECCCCHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAKSIQEKVFKNPKIEIMWDSVVEEIKGDGIVESAVFKNKKTGEITEYFADEDDGTFGIF
HHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHCCCCCCCEEEE
VFVGYLPINNLFKDIVIMNEAGYIKTNDRMETNIEGIFAAGDIREKSLRQVVTAAADGAI
EEEEHHCHHHHHHHEEEECCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHH
AAVEAYKYVEDTF
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8223622; 2537814 [H]