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The map label for this gene is pgcA [H]

Identifier: 170755958

GI number: 170755958

Start: 3370172

End: 3371899

Strand: Reverse

Name: pgcA [H]

Synonym: CLD_1425

Alternate gene names: 170755958

Gene position: 3371899-3370172 (Counterclockwise)

Preceding gene: 170757176

Following gene: 170755556

Centisome position: 85.19

GC content: 25.64

Gene sequence:

>1728_bases
ATGAACTATAAATATGCTTACAATTCATGGATGAATTCTTGTTTTTTAGAAAAAAGAGAAAAAGAACAATTAAAAAACAT
AGATGATGAACAAGAGATAAAAGACAGATTCTATAAAGATTTAAGCTTTGGAACAGGTGGAATAAGAGGGGTAGCTGGTT
TAGGTACAAATAGAATAAATAAATATACTATAGCTAAAGCTACGGAAGGGTTATCAAATTATCTAATTCATAATTTTAAA
GAAAAAGGTATATCTGTTGCAATAGCCTATGATTGTAGAAATGATTCTTTAGATTTCGCTAAAAAAGCTAGTGAAGTATT
ATGCTCATATGGTATAAGAGTATATATATTTAGTGATATAATGTGCACACCTATACTATCCTATGCTGTTAGAGAACTAA
AATGTAAAGCTGGAATAGTTATAACTGCATCACATAATAGTAAAGAGTATAATGGGTACAAAGTATATAATCATAATGGA
AATCAAATAACAGATAAAGAAGCACAAGAGATAGCTGAGTATATAAAAGAAGTAGAGGACTTAGGTTGTATAAAGTATAT
GGATATAAATGATGCAAAGGAAAAAAATTTATACGAATTTGTACCAATAGAGATATTAAATAAATATTTTTATAATGTAA
AAAATTTAACTTTAAGAAAAGATATTGTAAAAAATTATGAAAAGAATTTTAAAATATTATATACACCACTACATGGAACT
GGAAATGTTCCAGTAAGAAGAGCCTTATGTGAAATTGGATATAATAATGTTTTTGTAGTTAAGGATCAAGAAAAACCCAA
TGGAAATTTCCCAACAGTAAAATATCCTAATCCAGAGGATAATAAAGCTTTCTATGCTTCTTTAAAAGAGGCAGAAAATA
TAAATCCTGATGTAATAATAGCTACCGATCCTGATTGTGATAGAGTAGGGATTATGGTTAGGGATCATAGTACAAGATAT
GTAGCTTTAAATGGAAATGAATTAGGTGTAATTCTTACTAATTATATATTAAGTTCCTTAGAAGAAGAAAAAAAAATACC
TGAAAATTCAGTGCTTTTAAAAACCATAGTAACTACAGATATGGTTAAAAGTATATGTAAAGACTATGGAGTTAAGGTAG
AAGAAGTTTTAACAGGTTTTAAATATATAGGAGAGAAAATAGAAGAATTTAAGAAAAATGGGCAAAATAAATTTATATTT
GGGTTTGAGGAAAGCTATGGATATTTATTTGGGGACTTTGTTAGAGAGAAAGATGGAATAATAAGCTCTGTGTTAATATG
TGAAATGGCTTTATATTATAAGATTCAAAATAAAAATTTATTTGATGTTTTAACAGAGCTTTATGATAAATATGGATATT
ATAAAGAAAAATTAATATCCATGGAGTTTAAAGGAGAAGAGGGCAAAAATAAAATAGAAAATATAATCAATAATTTAAGA
ATTCATGATTCTAAAACTATATTTAATGAAGAAATACTAATAAAAGAAGATTATAAAACAGGTTTAAAAATAAATATGAA
TAAAAAGAAAGAATATATTAATAAGCTTCCTAAATCTAATGTTTTAAAATTCCATTTAAATAACGGTACTAATTTTGTAA
TTAGACCATCTGGAACAGAACCTAAAATAAAAATATATTTATCATCAGTACACACAACAGCTGAAGGGGCTGAAATGAAG
ATAAATAAGCTAGAAAAAAATATAAAGAATATGATAAATAAATTTTAA

Upstream 100 bases:

>100_bases
TATAGATTTTATAAAATAAAATGGGGTGAAATTTTATTTAGAGTACAATTATTTATGTTTTTTAATATAATGTAGTATGA
AATTTTATTGGAGGTAGTAA

Downstream 100 bases:

>100_bases
AACTACAAATATTTAAATTATGCATAGGATAATTTAAAAAATTATCCTATGCATAATTTAAATATTTTTGTATTTTCATT
GTTTAATCATTTATATTATT

Product: phosphoglucomutase/phosphomannomutase family protein

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MNYKYAYNSWMNSCFLEKREKEQLKNIDDEQEIKDRFYKDLSFGTGGIRGVAGLGTNRINKYTIAKATEGLSNYLIHNFK
EKGISVAIAYDCRNDSLDFAKKASEVLCSYGIRVYIFSDIMCTPILSYAVRELKCKAGIVITASHNSKEYNGYKVYNHNG
NQITDKEAQEIAEYIKEVEDLGCIKYMDINDAKEKNLYEFVPIEILNKYFYNVKNLTLRKDIVKNYEKNFKILYTPLHGT
GNVPVRRALCEIGYNNVFVVKDQEKPNGNFPTVKYPNPEDNKAFYASLKEAENINPDVIIATDPDCDRVGIMVRDHSTRY
VALNGNELGVILTNYILSSLEEEKKIPENSVLLKTIVTTDMVKSICKDYGVKVEEVLTGFKYIGEKIEEFKKNGQNKFIF
GFEESYGYLFGDFVREKDGIISSVLICEMALYYKIQNKNLFDVLTELYDKYGYYKEKLISMEFKGEEGKNKIENIINNLR
IHDSKTIFNEEILIKEDYKTGLKINMNKKKEYINKLPKSNVLKFHLNNGTNFVIRPSGTEPKIKIYLSSVHTTAEGAEMK
INKLEKNIKNMINKF

Sequences:

>Translated_575_residues
MNYKYAYNSWMNSCFLEKREKEQLKNIDDEQEIKDRFYKDLSFGTGGIRGVAGLGTNRINKYTIAKATEGLSNYLIHNFK
EKGISVAIAYDCRNDSLDFAKKASEVLCSYGIRVYIFSDIMCTPILSYAVRELKCKAGIVITASHNSKEYNGYKVYNHNG
NQITDKEAQEIAEYIKEVEDLGCIKYMDINDAKEKNLYEFVPIEILNKYFYNVKNLTLRKDIVKNYEKNFKILYTPLHGT
GNVPVRRALCEIGYNNVFVVKDQEKPNGNFPTVKYPNPEDNKAFYASLKEAENINPDVIIATDPDCDRVGIMVRDHSTRY
VALNGNELGVILTNYILSSLEEEKKIPENSVLLKTIVTTDMVKSICKDYGVKVEEVLTGFKYIGEKIEEFKKNGQNKFIF
GFEESYGYLFGDFVREKDGIISSVLICEMALYYKIQNKNLFDVLTELYDKYGYYKEKLISMEFKGEEGKNKIENIINNLR
IHDSKTIFNEEILIKEDYKTGLKINMNKKKEYINKLPKSNVLKFHLNNGTNFVIRPSGTEPKIKIYLSSVHTTAEGAEMK
INKLEKNIKNMINKF
>Mature_575_residues
MNYKYAYNSWMNSCFLEKREKEQLKNIDDEQEIKDRFYKDLSFGTGGIRGVAGLGTNRINKYTIAKATEGLSNYLIHNFK
EKGISVAIAYDCRNDSLDFAKKASEVLCSYGIRVYIFSDIMCTPILSYAVRELKCKAGIVITASHNSKEYNGYKVYNHNG
NQITDKEAQEIAEYIKEVEDLGCIKYMDINDAKEKNLYEFVPIEILNKYFYNVKNLTLRKDIVKNYEKNFKILYTPLHGT
GNVPVRRALCEIGYNNVFVVKDQEKPNGNFPTVKYPNPEDNKAFYASLKEAENINPDVIIATDPDCDRVGIMVRDHSTRY
VALNGNELGVILTNYILSSLEEEKKIPENSVLLKTIVTTDMVKSICKDYGVKVEEVLTGFKYIGEKIEEFKKNGQNKFIF
GFEESYGYLFGDFVREKDGIISSVLICEMALYYKIQNKNLFDVLTELYDKYGYYKEKLISMEFKGEEGKNKIENIINNLR
IHDSKTIFNEEILIKEDYKTGLKINMNKKKEYINKLPKSNVLKFHLNNGTNFVIRPSGTEPKIKIYLSSVHTTAEGAEMK
INKLEKNIKNMINKF

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=542, Percent_Identity=32.6568265682657, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI31377548, Length=584, Percent_Identity=32.7054794520548, Blast_Score=276, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71993870, Length=554, Percent_Identity=31.9494584837545, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71993878, Length=311, Percent_Identity=34.4051446945338, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6323934, Length=582, Percent_Identity=29.553264604811, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI20129809, Length=563, Percent_Identity=28.7744227353464, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24653722, Length=535, Percent_Identity=28.2242990654206, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24651977, Length=519, Percent_Identity=28.131021194605, Blast_Score=216, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 66325; Mature: 66325

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKYAYNSWMNSCFLEKREKEQLKNIDDEQEIKDRFYKDLSFGTGGIRGVAGLGTNRIN
CCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCC
KYTIAKATEGLSNYLIHNFKEKGISVAIAYDCRNDSLDFAKKASEVLCSYGIRVYIFSDI
EEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHH
MCTPILSYAVRELKCKAGIVITASHNSKEYNGYKVYNHNGNQITDKEAQEIAEYIKEVED
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LGCIKYMDINDAKEKNLYEFVPIEILNKYFYNVKNLTLRKDIVKNYEKNFKILYTPLHGT
CCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCC
GNVPVRRALCEIGYNNVFVVKDQEKPNGNFPTVKYPNPEDNKAFYASLKEAENINPDVII
CCCHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCEEE
ATDPDCDRVGIMVRDHSTRYVALNGNELGVILTNYILSSLEEEKKIPENSVLLKTIVTTD
EECCCCCEEEEEEEECCEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
MVKSICKDYGVKVEEVLTGFKYIGEKIEEFKKNGQNKFIFGFEESYGYLFGDFVREKDGI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCH
ISSVLICEMALYYKIQNKNLFDVLTELYDKYGYYKEKLISMEFKGEEGKNKIENIINNLR
HHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCHHHHHHEEEEECCCCCHHHHHHHHHHCE
IHDSKTIFNEEILIKEDYKTGLKINMNKKKEYINKLPKSNVLKFHLNNGTNFVIRPSGTE
ECCCCEEECCEEEEEECCCCCCEEECCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCC
PKIKIYLSSVHTTAEGAEMKINKLEKNIKNMINKF
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYKYAYNSWMNSCFLEKREKEQLKNIDDEQEIKDRFYKDLSFGTGGIRGVAGLGTNRIN
CCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCC
KYTIAKATEGLSNYLIHNFKEKGISVAIAYDCRNDSLDFAKKASEVLCSYGIRVYIFSDI
EEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHH
MCTPILSYAVRELKCKAGIVITASHNSKEYNGYKVYNHNGNQITDKEAQEIAEYIKEVED
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LGCIKYMDINDAKEKNLYEFVPIEILNKYFYNVKNLTLRKDIVKNYEKNFKILYTPLHGT
CCCEEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCC
GNVPVRRALCEIGYNNVFVVKDQEKPNGNFPTVKYPNPEDNKAFYASLKEAENINPDVII
CCCHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCEEE
ATDPDCDRVGIMVRDHSTRYVALNGNELGVILTNYILSSLEEEKKIPENSVLLKTIVTTD
EECCCCCEEEEEEEECCEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
MVKSICKDYGVKVEEVLTGFKYIGEKIEEFKKNGQNKFIFGFEESYGYLFGDFVREKDGI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCH
ISSVLICEMALYYKIQNKNLFDVLTELYDKYGYYKEKLISMEFKGEEGKNKIENIINNLR
HHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCHHHHHHEEEEECCCCCHHHHHHHHHHCE
IHDSKTIFNEEILIKEDYKTGLKINMNKKKEYINKLPKSNVLKFHLNNGTNFVIRPSGTE
ECCCCEEECCEEEEEECCCCCCEEECCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCC
PKIKIYLSSVHTTAEGAEMKINKLEKNIKNMINKF
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]