Click here to switch to the map view.

The map label for this gene is lip2 [H]

Identifier: 170755893

GI number: 170755893

Start: 2372678

End: 2373724

Strand: Reverse

Name: lip2 [H]

Synonym: CLD_2393

Alternate gene names: 170755893

Gene position: 2373724-2372678 (Counterclockwise)

Preceding gene: 170755516

Following gene: 170757164

Centisome position: 59.97

GC content: 30.56

Gene sequence:

>1047_bases
ATGGAGGTAAATGAAGTGAAAAAAGTAATAAAGGTAGTATCAGTTATTCTAGTTATACTTGTAATATCTGGATTTTTTAT
TATTAAAAATTTAACTGAGACCAAGGATGGTAAGCTTAATATGTATGTTGCTGCAAACTTGCAGTTATATAAAATCCTTA
ATCTTAAATCAATCAATAGTAAATCAATTGAAGAAATTAGAGGAAACTTAAATAAGCAATCAACTAAGTGGTCCAATAAA
CCTATACTATTTTCCAATATCAAAAATCTTGATATAAAAATGAACAATGAGAAAATACCAGTACGAATATATACACCTGA
AAATGGTAGTAATTTTCCTATAATCATTTATTCACATGGTGGTTTTTGGATTGGAGGAAATGTTGATACTAGTGATAGGG
TCTGTAGAAAGCTTTCACAGAACACAAAAGCAATTGTAATATCTGTAAACTATAGGCTTGCGCCAGAAAATTCTTTTCCC
GCTGGTCTTAATGATGTATATAATGTGCTTCAGTGGACTTATAAAAACGCAAAAAGCATAAATGGAGATGAAAAACATAT
AGCAGTTGTAGGGGATAGTGCAGGTGGAAATCTTTCTGCTGCAGTTTCATCAATGTCGCGGGATAAAAATGGGCCTCCTA
TAACATGTCAGGTATTAATATATCCATCTACAAATATATTTGAACTGAACAGTAAATCCTGGTCTTATTTTTCTAATAGT
GTTAATGTTTCAAGAGAAGATATGGAAAAGTATATTTCAATTTATGCACCGAAAAAAGAAGATAGAAAAAATCCTTATGC
ATCTCCACTTTTATCTAAGGACTTTAGCAAATTACCTGATACGCTTGTAGTAACAGCAGAAATTGATCCTCTTAGAGATG
AAGGAGAAGCGTATGCTAATAAACTAAAGGAATCTGGGGTTAAAGTAGATGTTGCTCGATATAAAGGTATTACTCATGGA
TTTATTACAATGGATAAAATTACAAATAAAGCAGACGAAGCATTAAATCAAATTTCGTTATATATACAAAAAGAATTTCA
AAAATAA

Upstream 100 bases:

>100_bases
TTAGAAATTAATGTTGAAGGATTTTAAGTATATTAAAATACGTAAAGGAAAAAATATAAAAATAAATGTAGTTATTTTTA
TTGTAGAATTTTTATAGCGG

Downstream 100 bases:

>100_bases
ACTTAATATAGTTATTTTATCAAAAAATTTATTATAAGGATAATGTAAGTTATAACTATCTTATTAGCGAACTTATTAGC
AAAAGCCATATTAATGGCGA

Product: putative lipase/esterase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEVNEVKKVIKVVSVILVILVISGFFIIKNLTETKDGKLNMYVAANLQLYKILNLKSINSKSIEEIRGNLNKQSTKWSNK
PILFSNIKNLDIKMNNEKIPVRIYTPENGSNFPIIIYSHGGFWIGGNVDTSDRVCRKLSQNTKAIVISVNYRLAPENSFP
AGLNDVYNVLQWTYKNAKSINGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPPITCQVLIYPSTNIFELNSKSWSYFSNS
VNVSREDMEKYISIYAPKKEDRKNPYASPLLSKDFSKLPDTLVVTAEIDPLRDEGEAYANKLKESGVKVDVARYKGITHG
FITMDKITNKADEALNQISLYIQKEFQK

Sequences:

>Translated_348_residues
MEVNEVKKVIKVVSVILVILVISGFFIIKNLTETKDGKLNMYVAANLQLYKILNLKSINSKSIEEIRGNLNKQSTKWSNK
PILFSNIKNLDIKMNNEKIPVRIYTPENGSNFPIIIYSHGGFWIGGNVDTSDRVCRKLSQNTKAIVISVNYRLAPENSFP
AGLNDVYNVLQWTYKNAKSINGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPPITCQVLIYPSTNIFELNSKSWSYFSNS
VNVSREDMEKYISIYAPKKEDRKNPYASPLLSKDFSKLPDTLVVTAEIDPLRDEGEAYANKLKESGVKVDVARYKGITHG
FITMDKITNKADEALNQISLYIQKEFQK
>Mature_348_residues
MEVNEVKKVIKVVSVILVILVISGFFIIKNLTETKDGKLNMYVAANLQLYKILNLKSINSKSIEEIRGNLNKQSTKWSNK
PILFSNIKNLDIKMNNEKIPVRIYTPENGSNFPIIIYSHGGFWIGGNVDTSDRVCRKLSQNTKAIVISVNYRLAPENSFP
AGLNDVYNVLQWTYKNAKSINGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPPITCQVLIYPSTNIFELNSKSWSYFSNS
VNVSREDMEKYISIYAPKKEDRKNPYASPLLSKDFSKLPDTLVVTAEIDPLRDEGEAYANKLKESGVKVDVARYKGITHG
FITMDKITNKADEALNQISLYIQKEFQK

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI68299767, Length=299, Percent_Identity=28.4280936454849, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI157041239, Length=288, Percent_Identity=26.7361111111111, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI61966717, Length=289, Percent_Identity=26.643598615917, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI206597554, Length=288, Percent_Identity=26.7361111111111, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI68051721, Length=275, Percent_Identity=25.4545454545455, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786682, Length=246, Percent_Identity=27.6422764227642, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17567059, Length=276, Percent_Identity=29.7101449275362, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17540028, Length=278, Percent_Identity=28.4172661870504, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71996133, Length=268, Percent_Identity=27.2388059701493, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72001146, Length=149, Percent_Identity=33.5570469798658, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 39032; Mature: 39032

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVNEVKKVIKVVSVILVILVISGFFIIKNLTETKDGKLNMYVAANLQLYKILNLKSINS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECEEEEEEECCCCCCH
KSIEEIRGNLNKQSTKWSNKPILFSNIKNLDIKMNNEKIPVRIYTPENGSNFPIIIYSHG
HHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEECCCCCCCCCEEEECCC
GFWIGGNVDTSDRVCRKLSQNTKAIVISVNYRLAPENSFPAGLNDVYNVLQWTYKNAKSI
CEEECCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCC
NGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPPITCQVLIYPSTNIFELNSKSWSYFSNS
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCEEECCC
VNVSREDMEKYISIYAPKKEDRKNPYASPLLSKDFSKLPDTLVVTAEIDPLRDEGEAYAN
CCCCHHHHHHHHEEECCCCHHCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHH
KLKESGVKVDVARYKGITHGFITMDKITNKADEALNQISLYIQKEFQK
HHHHCCCEEEEHHHCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVNEVKKVIKVVSVILVILVISGFFIIKNLTETKDGKLNMYVAANLQLYKILNLKSINS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECEEEEEEECCCCCCH
KSIEEIRGNLNKQSTKWSNKPILFSNIKNLDIKMNNEKIPVRIYTPENGSNFPIIIYSHG
HHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEECCCCCCCCCEEEECCC
GFWIGGNVDTSDRVCRKLSQNTKAIVISVNYRLAPENSFPAGLNDVYNVLQWTYKNAKSI
CEEECCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCC
NGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPPITCQVLIYPSTNIFELNSKSWSYFSNS
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEECCCCCEEECCC
VNVSREDMEKYISIYAPKKEDRKNPYASPLLSKDFSKLPDTLVVTAEIDPLRDEGEAYAN
CCCCHHHHHHHHEEECCCCHHCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHH
KLKESGVKVDVARYKGITHGFITMDKITNKADEALNQISLYIQKEFQK
HHHHCCCEEEEHHHCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]