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The map label for this gene is arsR [H]

Identifier: 170755886

GI number: 170755886

Start: 881585

End: 881902

Strand: Direct

Name: arsR [H]

Synonym: CLD_3801

Alternate gene names: 170755886

Gene position: 881585-881902 (Clockwise)

Preceding gene: 170755031

Following gene: 170756710

Centisome position: 22.27

GC content: 25.47

Gene sequence:

>318_bases
ATGAACTTAAATTATGATGATAATGCAAAAATTATTAAAGCATTATCAGATGGTAGTAGATTAAAAATAATTGATATGTT
GTCCTGTGGAGAAAAGTGTACTTGTGATATATTAGAACATTTTGATTTTACACAGCCAACACTTTCTCATCATATGAAGG
TTCTAATGGATTGTGGCCTTGTAGAATCTAGAAAAGAAGGTTTATGGTCATATTATTCATTAAACATTACTAATTGCAAT
AAATTAATTTTATTTTTCATGAATATTATAACGGATACAGATGAATGTATCTGTAAAGATAAAACAAAATGTAAATAA

Upstream 100 bases:

>100_bases
TGTAGGTATATTTAGTGTTGATAAATATAAAGTATATTGACATTATATAGAATGTGATCTATACTATACATAGATAAATA
TCTATATTGGAGGGAACTCA

Downstream 100 bases:

>100_bases
TAAAAAGCTTAGTTAAGAGAATTAAATTATATTACATTAAGATAATGAAGTTTTATAAAAGAAGTTTGGATAGTACCTAA
GAACCTTACGACTTTAGTCG

Product: arsenical resistance operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MNLNYDDNAKIIKALSDGSRLKIIDMLSCGEKCTCDILEHFDFTQPTLSHHMKVLMDCGLVESRKEGLWSYYSLNITNCN
KLILFFMNIITDTDECICKDKTKCK

Sequences:

>Translated_105_residues
MNLNYDDNAKIIKALSDGSRLKIIDMLSCGEKCTCDILEHFDFTQPTLSHHMKVLMDCGLVESRKEGLWSYYSLNITNCN
KLILFFMNIITDTDECICKDKTKCK
>Mature_105_residues
MNLNYDDNAKIIKALSDGSRLKIIDMLSCGEKCTCDILEHFDFTQPTLSHHMKVLMDCGLVESRKEGLWSYYSLNITNCN
KLILFFMNIITDTDECICKDKTKCK

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12093; Mature: 12093

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
12.4 %Cys+Met (Translated Protein)
7.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
12.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNYDDNAKIIKALSDGSRLKIIDMLSCGEKCTCDILEHFDFTQPTLSHHMKVLMDCGL
CCCCCCCCHHHEEECCCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCC
VESRKEGLWSYYSLNITNCNKLILFFMNIITDTDECICKDKTKCK
HHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCC
>Mature Secondary Structure
MNLNYDDNAKIIKALSDGSRLKIIDMLSCGEKCTCDILEHFDFTQPTLSHHMKVLMDCGL
CCCCCCCCHHHEEECCCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCC
VESRKEGLWSYYSLNITNCNKLILFFMNIITDTDECICKDKTKCK
HHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1534328 [H]