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The map label for this gene is bioD

Identifier: 170755845

GI number: 170755845

Start: 2453255

End: 2453938

Strand: Reverse

Name: bioD

Synonym: CLD_2317

Alternate gene names: 170755845

Gene position: 2453938-2453255 (Counterclockwise)

Preceding gene: 170754679

Following gene: 170754751

Centisome position: 62.0

GC content: 29.24

Gene sequence:

>684_bases
ATGGCAAGAGGAATATTTATAACAGCCACAGGAACTGATATTGGAAAAACTTACGTAACGGCTTTAATTATTAAGAGATT
AAGAGAAACTAATATAAATTGTGGATACTATAAAGCTGCTCTAAGCGGGGCAGAGAGAAGAGATGGTAAACTTATTGCAG
GAGATGCTAACTATGTATATAATATTGCCAACATAAAGGGAGATCCTAATGATGCAGTGAGTTATATATTTCAGCAAGCA
GTTTCTCCTCATTTAGCAGCAAAGTTAAATAATGTAGAAATATCTATGGAGAGGATAAAAAAAGATTTTTACTCTATTAA
AAATAAATATGATTATATAACTGTAGAAGGTAGTGGAGGAATAGTTTGTCCTATTTCCACAGGTAAAAAAAAAATAATGC
TTGACAATATCATAAAGATCTTTAAACTACCGGCTATTGTTGTAGCAGATGCAGGTCTTGGCACCATTAACAGTACAATT
TTAACCCTTCAATATATGAAAGAGAAAAATATATCTGTAAAAATGATTTTATTAAACAATTATAACCATGAAGATATAAT
TCATATAGAAAATAAGGGATACCTATCAGATAATTTACTAATTCCAGTTTATACATGTAATAAGAATGCTAATAATTTAG
AAATTCCAGTAGAAAAACTAATTGAAATCTATGAGGAGATATAA

Upstream 100 bases:

>100_bases
GAGTAAATGGAGCAATTTCTGGAGATATGCTAACTACTTTAGGAATTGAAACTTCTGAGGACATTAAAATGATAAAGAAT
TTAGGATTTGAGGTATAAAT

Downstream 100 bases:

>100_bases
TTTAGCATCTAACGCTATTGACAAACAATATTAATATGGTTAGTGTAATATTAATATTGTAATAAATTTAGAATGTTATA
GATTTGATGGGGAAATGGAG

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSGAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQA
VSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKKKIMLDNIIKIFKLPAIVVADAGLGTINSTI
LTLQYMKEKNISVKMILLNNYNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI

Sequences:

>Translated_227_residues
MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSGAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQA
VSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKKKIMLDNIIKIFKLPAIVVADAGLGTINSTI
LTLQYMKEKNISVKMILLNNYNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
>Mature_226_residues
ARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSGAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQAV
SPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKKKIMLDNIIKIFKLPAIVVADAGLGTINSTIL
TLQYMKEKNISVKMILLNNYNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=203, Percent_Identity=23.1527093596059, Blast_Score=75, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324385, Length=172, Percent_Identity=30.8139534883721, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25314; Mature: 25183

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSGAERRDGKLIAGDANYVY
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCEEEEECCCEEE
NIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGG
EEEECCCCCHHHHHHHHHHHCCCHHHHEECCEEEHHHHHHHHHHHHCCCCEEEEEECCCC
IVCPISTGKKKIMLDNIIKIFKLPAIVVADAGLGTINSTILTLQYMKEKNISVKMILLNN
EEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHEEEEEEHHCCCCEEEEEEEEC
YNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
CCCCCEEEECCCCEECCCCEEEEEEECCCCCCEECCHHHHHHHHHCC
>Mature Secondary Structure 
ARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSGAERRDGKLIAGDANYVY
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCEEEEECCCEEE
NIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGG
EEEECCCCCHHHHHHHHHHHCCCHHHHEECCEEEHHHHHHHHHHHHCCCCEEEEEECCCC
IVCPISTGKKKIMLDNIIKIFKLPAIVVADAGLGTINSTILTLQYMKEKNISVKMILLNN
EEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHEEEEEEHHCCCCEEEEEEEEC
YNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
CCCCCEEEECCCCEECCCCEEEEEEECCCCCCEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA