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The map label for this gene is hypB

Identifier: 170755769

GI number: 170755769

Start: 907483

End: 908151

Strand: Direct

Name: hypB

Synonym: CLD_3774

Alternate gene names: 170755769

Gene position: 907483-908151 (Clockwise)

Preceding gene: 170755029

Following gene: 170756575

Centisome position: 22.93

GC content: 34.23

Gene sequence:

>669_bases
ATGGACAAATATAAAGTTATTGAAATTAAGAAAAGTGTTTTCGAAGATAATGATCAACAAGCGAATTTGCTTAGGGAGGA
ATTAAGAAAAGAGAAGACTTTTTTATTAAACTTGATGTCATCACCAGGTTCAGGTAAAACAACAACTGTTTTAAGAACAA
TTGAAGCTTTGAAAGATGAAATGAACATTGGTGTTCTAGAAGCAGACATTGATTCTGAAGTTGATGCCCATACTGTTGCT
CAGGCTGGTGCAAAAGTAATCCAATTGCACACAGGTGGAATGTGTCATCTTGATGCAGATATGACCAAGCAAGGTCTATT
GGGTCTTGGAACAGAGGGAGTTGATTTTGCCATCTTAGAAAATGTAGGCAATTTGGTATGCCCAGCAGAATTTGACACTG
GTGCATCAAAAAATGCCATGATTTTAAGTGTACCAGAGGGGGACGACAAACCTTTGAAATATCCTTTAATGTTCTCTATT
GTTGATGTTGTATTAATTAATAAAATAGATGCAATAGCTAATTTTGACTTTGATTTTAAGGCAGTGGAAGAACATATAAA
AAAATTAAATCCTAATATTAAAGTTATCAAAATCTCTGCTAAAACTGGTGAGGGAATTGATGAATGGATCAACTGGATAC
GTACTGAAGTAAAAAATTGGAGGGTATAA

Upstream 100 bases:

>100_bases
ACGTAGCTGCTCTTTACTCCCACTTTGAAGAAGATGGGAGTATTAGAGTGGGTAGTCAGCGGATAAATAAACTTTAGTAT
AAAATGGGGGTATAGGTGAT

Downstream 100 bases:

>100_bases
ATAAGTAGCTGTAAAATTTAATTTAGGGGGAACAGATATGGTAAAGAAAAAAGTACTTGAACTGGCCAATAAGATTGCTG
GTGGGATTACTGGTGGGTTA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MDKYKVIEIKKSVFEDNDQQANLLREELRKEKTFLLNLMSSPGSGKTTTVLRTIEALKDEMNIGVLEADIDSEVDAHTVA
QAGAKVIQLHTGGMCHLDADMTKQGLLGLGTEGVDFAILENVGNLVCPAEFDTGASKNAMILSVPEGDDKPLKYPLMFSI
VDVVLINKIDAIANFDFDFKAVEEHIKKLNPNIKVIKISAKTGEGIDEWINWIRTEVKNWRV

Sequences:

>Translated_222_residues
MDKYKVIEIKKSVFEDNDQQANLLREELRKEKTFLLNLMSSPGSGKTTTVLRTIEALKDEMNIGVLEADIDSEVDAHTVA
QAGAKVIQLHTGGMCHLDADMTKQGLLGLGTEGVDFAILENVGNLVCPAEFDTGASKNAMILSVPEGDDKPLKYPLMFSI
VDVVLINKIDAIANFDFDFKAVEEHIKKLNPNIKVIKISAKTGEGIDEWINWIRTEVKNWRV
>Mature_222_residues
MDKYKVIEIKKSVFEDNDQQANLLREELRKEKTFLLNLMSSPGSGKTTTVLRTIEALKDEMNIGVLEADIDSEVDAHTVA
QAGAKVIQLHTGGMCHLDADMTKQGLLGLGTEGVDFAILENVGNLVCPAEFDTGASKNAMILSVPEGDDKPLKYPLMFSI
VDVVLINKIDAIANFDFDFKAVEEHIKKLNPNIKVIKISAKTGEGIDEWINWIRTEVKNWRV

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=216, Percent_Identity=40.7407407407407, Blast_Score=180, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 24630; Mature: 24630

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKYKVIEIKKSVFEDNDQQANLLREELRKEKTFLLNLMSSPGSGKTTTVLRTIEALKDE
CCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
MNIGVLEADIDSEVDAHTVAQAGAKVIQLHTGGMCHLDADMTKQGLLGLGTEGVDFAILE
CCCEEEEECCCCCCHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCEECCCCCCCHHHHH
NVGNLVCPAEFDTGASKNAMILSVPEGDDKPLKYPLMFSIVDVVLINKIDAIANFDFDFK
HCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
AVEEHIKKLNPNIKVIKISAKTGEGIDEWINWIRTEVKNWRV
HHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDKYKVIEIKKSVFEDNDQQANLLREELRKEKTFLLNLMSSPGSGKTTTVLRTIEALKDE
CCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
MNIGVLEADIDSEVDAHTVAQAGAKVIQLHTGGMCHLDADMTKQGLLGLGTEGVDFAILE
CCCEEEEECCCCCCHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCEECCCCCCCHHHHH
NVGNLVCPAEFDTGASKNAMILSVPEGDDKPLKYPLMFSIVDVVLINKIDAIANFDFDFK
HCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
AVEEHIKKLNPNIKVIKISAKTGEGIDEWINWIRTEVKNWRV
HHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]