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The map label for this gene is aspB

Identifier: 170755740

GI number: 170755740

Start: 2514652

End: 2515845

Strand: Reverse

Name: aspB

Synonym: CLD_2242

Alternate gene names: 170755740

Gene position: 2515845-2514652 (Counterclockwise)

Preceding gene: 170757118

Following gene: 170755446

Centisome position: 63.56

GC content: 28.98

Gene sequence:

>1194_bases
ATGAAATTATCTAAAAAAGCAATAGAAATACAACCATCTTTAACATTAGAAATAACTGCAAAGGCTAAAAAAATGAAAGC
AGAAGGTATAGATGTTATAGGTTTTGGAGCGGGAGAGCCGGATTTTAACACACCGGAGAATATACAAAAAGCAGCTATGT
TAGCCATAGAAGAAGGATATACTAAATATACAGCAGCTTCAGGTATATTAGAATTAAAACAGGCTATAGTAGATAAATTT
AAAAAAGACAATGGTTTAAACTATGAAACTAGTGAAATAATAGTAAGTAATGGAGCAAAGCAATGTCTTTCAAATTTATT
TGAAGCCATATTAAATGAAGGAGATGAGATTTTAATAGCTAAACCTTATTGGGTAAGCTATCCAGAACTTATAAAACTAT
ATGGTGGAGTACCTGTTTTTGTAGATACAAAAGAAGAAAATCATTTTAAATATGAAATAGAAGAATTAGAAAATAAAGTA
ACAGATAAAACAAAGGCCATCATAATAAATAGCCCTAACAATCCTACAGGAACAGTATATAGCAAAGAAGATTTAGAAGC
CTTAGCTATTTTTGCAAAAAAATATGATTTATTAATAATAGCAGATGAAATATACGAAATGTTAATGTATGGAGAAGAAA
ATCATATAAGTATAGCAAGTTTATCAGAGGATGCTTTTAAAAGGACTGTAGTAATAAATGGTATGTCTAAATCCTATTCC
ATGACCGGTTGGAGAATAGGATATGCAGCGGGTCCTTTGGATATAATAAAAGTGATGAGTAATATACAAAGCCATACCAC
ATCTAATCCAAACTCTATAGCTCAATATGCATCCTTAGAAGCTCTTAAAGGAGATAAAACCTATGTTAAAAATATGATAG
TAGAGTTTAAAAAGAGAAGAGATTATATGGTGAATAAAGTAAATTCTATAGGAAATTTGTCATCTATAAATCCTAAAGGA
GCTTTTTATGTAATGGTTAATATATCAAAATCTATGGAAAAAACTATAAAAGGCAATACTATAAAGGATTCTATAAGTTT
TTCAAAAATTTTATTAGAAGAAGAAAAGGTAGCGGTAGTGCCAGGTATAGCCTTTGGTGATGATAATTTTATAAGATTAT
CCTATGCTACATCTATGGAGAATATAGAAAGAGGATTAGATAGAATAGAAAAATTCATGAAAAAATTGGATTAA

Upstream 100 bases:

>100_bases
TACTGGAAGCTATTTTAAGTAATTATTAAAATTAAACTTATGAGCAATAAATTTAGTAATAATTTATTTTAAATTTAGAA
TAAAAAGTGGAGGCAAAAAT

Downstream 100 bases:

>100_bases
TAATATCATGTAATGGTTTATAAAAACTGTTGAAATCTGTAGAAAAAAATGGTATAATATTACGTATATGTTTTTTAAGA
AACAGATAGATTATAAAAGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGYTKYTAASGILELKQAIVDKF
KKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIAKPYWVSYPELIKLYGGVPVFVDTKEENHFKYEIEELENKV
TDKTKAIIINSPNNPTGTVYSKEDLEALAIFAKKYDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTYVKNMIVEFKKRRDYMVNKVNSIGNLSSINPKG
AFYVMVNISKSMEKTIKGNTIKDSISFSKILLEEEKVAVVPGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD

Sequences:

>Translated_397_residues
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGYTKYTAASGILELKQAIVDKF
KKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIAKPYWVSYPELIKLYGGVPVFVDTKEENHFKYEIEELENKV
TDKTKAIIINSPNNPTGTVYSKEDLEALAIFAKKYDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTYVKNMIVEFKKRRDYMVNKVNSIGNLSSINPKG
AFYVMVNISKSMEKTIKGNTIKDSISFSKILLEEEKVAVVPGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD
>Mature_397_residues
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGYTKYTAASGILELKQAIVDKF
KKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIAKPYWVSYPELIKLYGGVPVFVDTKEENHFKYEIEELENKV
TDKTKAIIINSPNNPTGTVYSKEDLEALAIFAKKYDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTYVKNMIVEFKKRRDYMVNKVNSIGNLSSINPKG
AFYVMVNISKSMEKTIKGNTIKDSISFSKILLEEEKVAVVPGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=371, Percent_Identity=28.8409703504043, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI56713254, Length=371, Percent_Identity=28.8409703504043, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI95147551, Length=319, Percent_Identity=30.0940438871473, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI169881279, Length=319, Percent_Identity=30.0940438871473, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI169881281, Length=230, Percent_Identity=30.8695652173913, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=24.2268041237113, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI187936925, Length=374, Percent_Identity=22.7272727272727, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI14211921, Length=374, Percent_Identity=22.7272727272727, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI149944424, Length=325, Percent_Identity=20.6153846153846, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI215599424, Length=407, Percent_Identity=22.1130221130221, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI19263340, Length=407, Percent_Identity=22.1130221130221, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI7705897, Length=395, Percent_Identity=24.3037974683544, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI33469970, Length=395, Percent_Identity=24.3037974683544, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4885351, Length=372, Percent_Identity=24.1935483870968, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=26.1780104712042, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788722, Length=397, Percent_Identity=30.2267002518892, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788627, Length=396, Percent_Identity=27.5252525252525, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787909, Length=373, Percent_Identity=21.4477211796247, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=427, Percent_Identity=28.3372365339578, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71994476, Length=427, Percent_Identity=28.3372365339578, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=28.90625, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=28.5, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71981209, Length=376, Percent_Identity=23.6702127659574, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71981215, Length=160, Percent_Identity=25, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=25.1889168765743, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=345, Percent_Identity=20.8695652173913, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573069, Length=421, Percent_Identity=26.603325415677, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24646114, Length=421, Percent_Identity=26.603325415677, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI28573067, Length=421, Percent_Identity=26.603325415677, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI28573065, Length=421, Percent_Identity=26.603325415677, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=23.2189973614776, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45551451, Length=366, Percent_Identity=23.4972677595628, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641770, Length=365, Percent_Identity=23.5616438356164, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641760, Length=365, Percent_Identity=23.5616438356164, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641768, Length=365, Percent_Identity=23.5616438356164, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641766, Length=365, Percent_Identity=23.5616438356164, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641764, Length=365, Percent_Identity=23.5616438356164, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44345; Mature: 44345

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGY
CCCCCCEEEECCCEEEEEECCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTAASGILELKQAIVDKFKKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCHHHHHHHHHHHHHCCCCEEEEE
KPYWVSYPELIKLYGGVPVFVDTKEENHFKYEIEELENKVTDKTKAIIINSPNNPTGTVY
CCCCCCCHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCEE
SKEDLEALAIFAKKYDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCEEEEECCHHHHEEEEEEECCCCCCC
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTYVKNMIVEFKKRR
CCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DYMVNKVNSIGNLSSINPKGAFYVMVNISKSMEKTIKGNTIKDSISFSKILLEEEKVAVV
HHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEE
PGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD
CCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGY
CCCCCCEEEECCCEEEEEECCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTAASGILELKQAIVDKFKKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCHHHHHHHHHHHHHCCCCEEEEE
KPYWVSYPELIKLYGGVPVFVDTKEENHFKYEIEELENKVTDKTKAIIINSPNNPTGTVY
CCCCCCCHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCEE
SKEDLEALAIFAKKYDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYS
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCEEEEECCHHHHEEEEEEECCCCCCC
MTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTYVKNMIVEFKKRR
CCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DYMVNKVNSIGNLSSINPKGAFYVMVNISKSMEKTIKGNTIKDSISFSKILLEEEKVAVV
HHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEE
PGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD
CCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]