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The map label for this gene is insK [H]

Identifier: 170755557

GI number: 170755557

Start: 3047332

End: 3048075

Strand: Reverse

Name: insK [H]

Synonym: CLD_1724

Alternate gene names: 170755557

Gene position: 3048075-3047332 (Counterclockwise)

Preceding gene: 170755723

Following gene: 170754517

Centisome position: 77.01

GC content: 32.66

Gene sequence:

>744_bases
ATGGAATTCTATCAAGAATTACTGCCGCTAATAAAAAATGCTTATGAGGAAAAACAAGGAATATTAGGATATAGACAAAT
GACAATCAAGTTAAATCGTGAGCATGAGTTTCATGTAAATTCGAAAAGAATTTACAGACTTATGTCAATTCTGAATTTAA
AATCTGTTTGTCGTAAGAAGAAAAAGAATTACAAGAAAACAACACCACAAGTAACAGCAGAAAATATTTTAAATAGGAAT
TTTAATTCTGATAAATTCGGGGAGAAATGGCTTACAGATGTAACTGAGATGAAGTACGGAATTGGAGGCAAGGCTTATCT
AAGTGCCATATTAGACCTTGCTGACAAAAGCATTGTATCATTTGTAATTGGTCATTCTAATAATAATACTCTTGTTTTTA
AAACATTAGATATAGCTCATGAGCAGCATCCTGACGCAAAGCCTCTGTTTCACAGTGACCGAGGCTTTCAATATACCTCT
AAAAATTTTAAGAAAAAGTTAGATGATGCAGATATGACTCAAAGCATGTCCAGGGTATCACGTTGTATCAACAACGGTCC
GATGGAAGCATTCTGGGGCATGTTAAAATCTGAAATGTATTACTTGAGAAAGTTCAATTCATATAGTGAACTAGAAAGTG
TAATCCCTGATTATATAAATTATTACAACAATCAAAGATATCAGAAGCGTCTAAAATGTATGACACCTTTAGAATATCGA
GAGTATCTGAAATCTGTAGCATAA

Upstream 100 bases:

>100_bases
TAAGCATATAAACATTAGGATTAATGAGTAAATTTCTTCATCTATATTAAGATTTTCTCCTTCCTAAGGGGCCTTTACAC
TTACTATTACGAATAAGATA

Downstream 100 bases:

>100_bases
AATACCGCCAACTACAAAAGTAATTGCCGGTATCAAATATTTTTATTTTTTTCACTGTCTACTTGACAGGGAGCAGTTCA
TTTATCAACAGCCTGAAGGT

Product: IS3 family transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEFYQELLPLIKNAYEEKQGILGYRQMTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENILNRN
FNSDKFGEKWLTDVTEMKYGIGGKAYLSAILDLADKSIVSFVIGHSNNNTLVFKTLDIAHEQHPDAKPLFHSDRGFQYTS
KNFKKKLDDADMTQSMSRVSRCINNGPMEAFWGMLKSEMYYLRKFNSYSELESVIPDYINYYNNQRYQKRLKCMTPLEYR
EYLKSVA

Sequences:

>Translated_247_residues
MEFYQELLPLIKNAYEEKQGILGYRQMTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENILNRN
FNSDKFGEKWLTDVTEMKYGIGGKAYLSAILDLADKSIVSFVIGHSNNNTLVFKTLDIAHEQHPDAKPLFHSDRGFQYTS
KNFKKKLDDADMTQSMSRVSRCINNGPMEAFWGMLKSEMYYLRKFNSYSELESVIPDYINYYNNQRYQKRLKCMTPLEYR
EYLKSVA
>Mature_247_residues
MEFYQELLPLIKNAYEEKQGILGYRQMTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENILNRN
FNSDKFGEKWLTDVTEMKYGIGGKAYLSAILDLADKSIVSFVIGHSNNNTLVFKTLDIAHEQHPDAKPLFHSDRGFQYTS
KNFKKKLDDADMTQSMSRVSRCINNGPMEAFWGMLKSEMYYLRKFNSYSELESVIPDYINYYNNQRYQKRLKCMTPLEYR
EYLKSVA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=191, Percent_Identity=28.2722513089005, Blast_Score=81, Evalue=7e-16,
Organism=Escherichia coli, GI1789981, Length=239, Percent_Identity=38.0753138075314, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1788405, Length=170, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787263, Length=170, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786753, Length=170, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786570, Length=170, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786490, Length=170, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 29191; Mature: 29191

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFYQELLPLIKNAYEEKQGILGYRQMTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKK
CCHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KKNYKKTTPQVTAENILNRNFNSDKFGEKWLTDVTEMKYGIGGKAYLSAILDLADKSIVS
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FVIGHSNNNTLVFKTLDIAHEQHPDAKPLFHSDRGFQYTSKNFKKKLDDADMTQSMSRVS
HHHCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
RCINNGPMEAFWGMLKSEMYYLRKFNSYSELESVIPDYINYYNNQRYQKRLKCMTPLEYR
HHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHH
EYLKSVA
HHHHHCC
>Mature Secondary Structure
MEFYQELLPLIKNAYEEKQGILGYRQMTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKK
CCHHHHHHHHHHHHHHHHHCCHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KKNYKKTTPQVTAENILNRNFNSDKFGEKWLTDVTEMKYGIGGKAYLSAILDLADKSIVS
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FVIGHSNNNTLVFKTLDIAHEQHPDAKPLFHSDRGFQYTSKNFKKKLDDADMTQSMSRVS
HHHCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
RCINNGPMEAFWGMLKSEMYYLRKFNSYSELESVIPDYINYYNNQRYQKRLKCMTPLEYR
HHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHH
EYLKSVA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]