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The map label for this gene is fabD

Identifier: 170755402

GI number: 170755402

Start: 3915463

End: 3916407

Strand: Reverse

Name: fabD

Synonym: CLD_0885

Alternate gene names: 170755402

Gene position: 3916407-3915463 (Counterclockwise)

Preceding gene: 170755290

Following gene: 170754596

Centisome position: 98.94

GC content: 31.22

Gene sequence:

>945_bases
ATGTCAAAGATAGCTTTTATATTCTCAGGTCAAGGAGCTCAATATGTAGGTATGGGTAAGGAGTTATATGAAAGTATTCC
TGAATGCAGAGAAATATTTCATATAGCAGAGGAAGAATTACAAATACCTTTAACTAAAATATGTTTTGAAGGTCCAAAGG
AAGAAATAGATAAAACAGAAAATACCCAACCAGCAATATTAACCCTTAGTATTGCTGCTATGAAAGCATTAGAAAAGTAT
GGTATAAAGCCAGATGTTACAGCAGGTCTAAGTTTGGGAGAATATTCAGCTTTAGTTTGTAGTAATGTTATAGATTTTAA
AGAAGCAGTTTCTTTAGTAAGAAAAAGAGGACAATATATGGAGAATGCGGTGCCTAATGGTGTTGGGACTATGGCAGCTA
TAATAGGTCTTAAAAAAGAAGTAGTTAAGGAAATTTGTGATTGTATAAAAGAAGAAGGAATAGTTCAGATAGCAAATATT
AATTGTCCTGGACAGATTGTTATTTCCGGGGAAATAAAGGCAGTGGAAAAGGCCTGTGAGATAGCAAAAGAAAAAAGAGC
TTTAAGGTGTGTAAAACTTAGTGTTAGTGGTCCATTTCATAGTATTATGCTAAAGGAAGCTGGGGAAAAGTTATACGAAG
AGTTACAGAAAATACAGCTTGAATCTATAGAAGTTCCATTTACAACAAATGTAACAGGAGATTTTGTGAAAAATACCAGT
GAAATAAAAGATTTGTTAAAAAAGCAGGTTATGAGTACTGTACATTGGGAAGATTCTATAAAAGCAATGATAGATTTTGG
AGTAGATACTTTTATAGAAATAGGCCCTTCAAAGGTTTTATCAGGATTTGTTAAGAAAATAAATAGAAAAGTAAATATAT
TAAATGTAGAAGATATAGATTCCCTTAATAAAACAATAGAAAAACTAAAAACAATAAATAGTTAG

Upstream 100 bases:

>100_bases
TTATAAATAAGGAACAAACTTGTAGTGAAATTATAAATGAAATGTTTAATGAAGCCTATACACTATTAGGTTATAAATAA
TATTTATTTTGGAGGATACT

Downstream 100 bases:

>100_bases
GAGAGTTGAGTAATAATATGAAATGCTTAGAAGGTAAAACTGCGATAGTAACCGGAGCTAGTAGAGGCATAGGAAGAGCA
ATAGCTAAAAAATTAGCATC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSKIAFIFSGQGAQYVGMGKELYESIPECREIFHIAEEELQIPLTKICFEGPKEEIDKTENTQPAILTLSIAAMKALEKY
GIKPDVTAGLSLGEYSALVCSNVIDFKEAVSLVRKRGQYMENAVPNGVGTMAAIIGLKKEVVKEICDCIKEEGIVQIANI
NCPGQIVISGEIKAVEKACEIAKEKRALRCVKLSVSGPFHSIMLKEAGEKLYEELQKIQLESIEVPFTTNVTGDFVKNTS
EIKDLLKKQVMSTVHWEDSIKAMIDFGVDTFIEIGPSKVLSGFVKKINRKVNILNVEDIDSLNKTIEKLKTINS

Sequences:

>Translated_314_residues
MSKIAFIFSGQGAQYVGMGKELYESIPECREIFHIAEEELQIPLTKICFEGPKEEIDKTENTQPAILTLSIAAMKALEKY
GIKPDVTAGLSLGEYSALVCSNVIDFKEAVSLVRKRGQYMENAVPNGVGTMAAIIGLKKEVVKEICDCIKEEGIVQIANI
NCPGQIVISGEIKAVEKACEIAKEKRALRCVKLSVSGPFHSIMLKEAGEKLYEELQKIQLESIEVPFTTNVTGDFVKNTS
EIKDLLKKQVMSTVHWEDSIKAMIDFGVDTFIEIGPSKVLSGFVKKINRKVNILNVEDIDSLNKTIEKLKTINS
>Mature_313_residues
SKIAFIFSGQGAQYVGMGKELYESIPECREIFHIAEEELQIPLTKICFEGPKEEIDKTENTQPAILTLSIAAMKALEKYG
IKPDVTAGLSLGEYSALVCSNVIDFKEAVSLVRKRGQYMENAVPNGVGTMAAIIGLKKEVVKEICDCIKEEGIVQIANIN
CPGQIVISGEIKAVEKACEIAKEKRALRCVKLSVSGPFHSIMLKEAGEKLYEELQKIQLESIEVPFTTNVTGDFVKNTSE
IKDLLKKQVMSTVHWEDSIKAMIDFGVDTFIEIGPSKVLSGFVKKINRKVNILNVEDIDSLNKTIEKLKTINS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=29.6052631578947, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=37.6146788990826, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=43.4027777777778, Blast_Score=223, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=29.7297297297297, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=298, Percent_Identity=27.8523489932886, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=34.3234323432343, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34707; Mature: 34576

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAFIFSGQGAQYVGMGKELYESIPECREIFHIAEEELQIPLTKICFEGPKEEIDKTE
CCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHCCCC
NTQPAILTLSIAAMKALEKYGIKPDVTAGLSLGEYSALVCSNVIDFKEAVSLVRKRGQYM
CCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAVPNGVGTMAAIIGLKKEVVKEICDCIKEEGIVQIANINCPGQIVISGEIKAVEKACE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHHH
IAKEKRALRCVKLSVSGPFHSIMLKEAGEKLYEELQKIQLESIEVPFTTNVTGDFVKNTS
HHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHCCHH
EIKDLLKKQVMSTVHWEDSIKAMIDFGVDTFIEIGPSKVLSGFVKKINRKVNILNVEDID
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCEEEEEHHHHH
SLNKTIEKLKTINS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SKIAFIFSGQGAQYVGMGKELYESIPECREIFHIAEEELQIPLTKICFEGPKEEIDKTE
CCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHCCCC
NTQPAILTLSIAAMKALEKYGIKPDVTAGLSLGEYSALVCSNVIDFKEAVSLVRKRGQYM
CCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAVPNGVGTMAAIIGLKKEVVKEICDCIKEEGIVQIANINCPGQIVISGEIKAVEKACE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHHH
IAKEKRALRCVKLSVSGPFHSIMLKEAGEKLYEELQKIQLESIEVPFTTNVTGDFVKNTS
HHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHCCHH
EIKDLLKKQVMSTVHWEDSIKAMIDFGVDTFIEIGPSKVLSGFVKKINRKVNILNVEDID
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCEEEEEHHHHH
SLNKTIEKLKTINS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]