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The map label for this gene is noxA

Identifier: 170755183

GI number: 170755183

Start: 1477794

End: 1479020

Strand: Direct

Name: noxA

Synonym: CLD_3224

Alternate gene names: 170755183

Gene position: 1477794-1479020 (Clockwise)

Preceding gene: 170754395

Following gene: 170756446

Centisome position: 37.33

GC content: 29.34

Gene sequence:

>1227_bases
ATGAAATATGTGATAATAGGGGCTAGTGCAGCAGGAATTTCAGCAGTTAAAACTTTGAGAACATTAGATAAAGATTCTCA
AATAGTTATGATTTCTAAAGATGATAAAGTATATTCAAGATGTTTGTTGCATCATTTTATAGGTGGAAATAGAGAAATAG
AAGGATTATCTTTTATAGAAAAGGATTTTTTCGCTAAGTATAATGTAAAATGGATAAAAAATAAAAAAGTAGAAACTGTA
GATATAGATAAAAAGATAGTAAAAGTGCAAGGAGAAATTTCAGAACATTATGATAAATTGCTTATAGCGTCAGGATCTTA
CGCGTCTATACCACCAATTAAAAATCTAAGAGAAGCTAAAAGGGTGTACACTCTAAGAGATTTAGATGATGCAATAGCTA
TAAAAGAAGAGGCTAAAAAAATCAAAAAAGCAGTGGTAATAGGAGCAGGATTAGTAGGGATAGATGCGACTATGGGATTA
TTAGAGAACAATGTAGAAGTAACTGTTGTAGAAATGGGAAATAGAATGCTTCCACTGCAATTAGACCAAAGAGCATCAAA
AGCTTACGAAGAATTATTTAGAAAGCACAATGTTAATATAAAAACCAGTGTAGGAGCTGAAGAAGCTTTAATAGATGAGA
ATGGAAACGTTTGTGGAATAAAATTAAATAATGGTGAAAAGATAGATTGTGATATTATAGTTGTAGCAGCAGGAGTTAGA
CCTAATATAGATTTTATAAAGGATGAAAGAATAAAGATAGAAAGAGGCATAGTTATAAATGATAATTGTGAAACTACAGT
TAAAGATATATATGCTGCAGGAGACGTAACCTTTAGAGCACCTATATGGCCAATAGCTATGAAACAAGGAAGAATAGCTG
CCTATAATATGGCAGGAGAAAAAAAGTTATTAGATGATAATTTTGGTGCAAGAAATTCTATGAATTTTCTAGGAGTATAC
ACTATATCTTTAGGTTTAGTAGAGCCAAAAGATGACAGTTATAAAGTAGATATAATAGATAAAAATGGAGTTTATAAAAA
AATAATACACAAAGATGGAATCATATATGGAGCTATACTTCAGGGGGATATAGCTTATGCTGGAGTATTAACAGAGCTAA
TAAAAAATAAAATAGATATATCAAAAATAAATAAGGATATATTTGATATAAGTTTTGCTGACTTTTTTAATATAAAAGAA
AATGGAGAATTTAGTTACAGAAAATAA

Upstream 100 bases:

>100_bases
GGATGCAAATAAATTAGCAGAGATTAGTATAAAATTTTCTTTAATAAGAATTTGATTTTATAATATTATAAAAAATATTA
AGGCTCAGGAGGTAAACAAT

Downstream 100 bases:

>100_bases
GAAAAATATTTAGTGTTTCCATGAGGCTGTTGATAAACATATTTTATCAACAGCTTTTTAATTTGTATAAAAAGTATTTT
AAGGTTTTTAAAATAATAAT

Product: nitrate reductase, NADH oxidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIEKDFFAKYNVKWIKNKKVETV
DIDKKIVKVQGEISEHYDKLLIASGSYASIPPIKNLREAKRVYTLRDLDDAIAIKEEAKKIKKAVVIGAGLVGIDATMGL
LENNVEVTVVEMGNRMLPLQLDQRASKAYEELFRKHNVNIKTSVGAEEALIDENGNVCGIKLNNGEKIDCDIIVVAAGVR
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAAYNMAGEKKLLDDNFGARNSMNFLGVY
TISLGLVEPKDDSYKVDIIDKNGVYKKIIHKDGIIYGAILQGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKE
NGEFSYRK

Sequences:

>Translated_408_residues
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIEKDFFAKYNVKWIKNKKVETV
DIDKKIVKVQGEISEHYDKLLIASGSYASIPPIKNLREAKRVYTLRDLDDAIAIKEEAKKIKKAVVIGAGLVGIDATMGL
LENNVEVTVVEMGNRMLPLQLDQRASKAYEELFRKHNVNIKTSVGAEEALIDENGNVCGIKLNNGEKIDCDIIVVAAGVR
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAAYNMAGEKKLLDDNFGARNSMNFLGVY
TISLGLVEPKDDSYKVDIIDKNGVYKKIIHKDGIIYGAILQGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKE
NGEFSYRK
>Mature_408_residues
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIEKDFFAKYNVKWIKNKKVETV
DIDKKIVKVQGEISEHYDKLLIASGSYASIPPIKNLREAKRVYTLRDLDDAIAIKEEAKKIKKAVVIGAGLVGIDATMGL
LENNVEVTVVEMGNRMLPLQLDQRASKAYEELFRKHNVNIKTSVGAEEALIDENGNVCGIKLNNGEKIDCDIIVVAAGVR
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAAYNMAGEKKLLDDNFGARNSMNFLGVY
TISLGLVEPKDDSYKVDIIDKNGVYKKIIHKDGIIYGAILQGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKE
NGEFSYRK

Specific function: Required for nitrite assimilation [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=312, Percent_Identity=29.8076923076923, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI65787454, Length=312, Percent_Identity=29.8076923076923, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI226437568, Length=312, Percent_Identity=29.8076923076923, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1789765, Length=403, Percent_Identity=26.0545905707196, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789065, Length=306, Percent_Identity=23.8562091503268, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788892, Length=220, Percent_Identity=26.3636363636364, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17559934, Length=319, Percent_Identity=25.0783699059561, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639257, Length=352, Percent_Identity=25.5681818181818, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281359715, Length=352, Percent_Identity=25.5681818181818, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281359713, Length=352, Percent_Identity=25.5681818181818, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24639250, Length=352, Percent_Identity=25.5681818181818, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18543267, Length=352, Percent_Identity=25.5681818181818, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24639252, Length=352, Percent_Identity=25.5681818181818, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24585130, Length=312, Percent_Identity=24.0384615384615, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24581020, Length=359, Percent_Identity=25.6267409470752, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573993, Length=359, Percent_Identity=25.6267409470752, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585384, Length=228, Percent_Identity=27.1929824561404, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR013027
- InterPro:   IPR005117
- InterPro:   IPR012744
- InterPro:   IPR017121
- InterPro:   IPR006067
- InterPro:   IPR006066
- InterPro:   IPR001327 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01077 NIR_SIR; PF03460 NIR_SIR_ferr; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.7.1.4 [H]

Molecular weight: Translated: 45549; Mature: 45549

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIE
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHH
KDFFAKYNVKWIKNKKVETVDIDKKIVKVQGEISEHYDKLLIASGSYASIPPIKNLREAK
HHHHHCCCEEEECCCCEEEEECCCEEEEEECCHHHCCCEEEEECCCCCCCCCHHHHHHHH
RVYTLRDLDDAIAIKEEAKKIKKAVVIGAGLVGIDATMGLLENNVEVTVVEMGNRMLPLQ
HEEEECCCCHHHHHHHHHHHHHHHEEEECCEEEHHHHHHHHCCCCEEEEEECCCEEECEE
LDQRASKAYEELFRKHNVNIKTSVGAEEALIDENGNVCGIKLNNGEKIDCDIIVVAAGVR
HHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCEEEEEECCCCEEEEEEEEEEECCC
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAAYNMAGE
CCCCEECCCCEEEECCEEECCCCCHHHHHHHCCCCEEEECCCCEEEECCCCEEEEECCCC
KKLLDDNFGARNSMNFLGVYTISLGLVEPKDDSYKVDIIDKNGVYKKIIHKDGIIYGAIL
CEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCCHHHHHCCCEEEEEEE
QGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKENGEFSYRK
ECCHHHHHHHHHHHHCCCCHHHHCCHHHEEEHHHEECCCCCCCCCCCC
>Mature Secondary Structure
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIE
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHH
KDFFAKYNVKWIKNKKVETVDIDKKIVKVQGEISEHYDKLLIASGSYASIPPIKNLREAK
HHHHHCCCEEEECCCCEEEEECCCEEEEEECCHHHCCCEEEEECCCCCCCCCHHHHHHHH
RVYTLRDLDDAIAIKEEAKKIKKAVVIGAGLVGIDATMGLLENNVEVTVVEMGNRMLPLQ
HEEEECCCCHHHHHHHHHHHHHHHEEEECCEEEHHHHHHHHCCCCEEEEEECCCEEECEE
LDQRASKAYEELFRKHNVNIKTSVGAEEALIDENGNVCGIKLNNGEKIDCDIIVVAAGVR
HHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCEEEEEECCCCEEEEEEEEEEECCC
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAAYNMAGE
CCCCEECCCCEEEECCEEECCCCCHHHHHHHCCCCEEEECCCCEEEECCCCEEEEECCCC
KKLLDDNFGARNSMNFLGVYTISLGLVEPKDDSYKVDIIDKNGVYKKIIHKDGIIYGAIL
CEECCCCCCCCCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCCHHHHHCCCEEEEEEE
QGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKENGEFSYRK
ECCHHHHHHHHHHHHCCCCHHHHCCHHHEEEHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7868621; 8969502; 9384377 [H]