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The map label for this gene is mtnA

Identifier: 170755175

GI number: 170755175

Start: 1400504

End: 1401553

Strand: Direct

Name: mtnA

Synonym: CLD_3299

Alternate gene names: 170755175

Gene position: 1400504-1401553 (Clockwise)

Preceding gene: 170756448

Following gene: 170754402

Centisome position: 35.38

GC content: 32.1

Gene sequence:

>1050_bases
ATGGCAGAGTTATTAGCTATAAAATGGGATGATAATAGAGATAAGTTAATACTTTTAGACCAAACAATATTACCAAATAA
AATTGAATATATAGAATACGATACTGCAGAAGGTGTATACGATTCCATAAAGGATATGATAGTTAGAGGAGCTCCGGCTA
TAGGAGTTACAGCGGCTTATGGTCTATATTTTGCAGCAAAAGTAGCACCAGAAGATAATTTTGAGAACTTCTTTAAATAT
CTAAAAGAAAAATCATCATATTTAGACTCAAGTAGACCAACAGCTGTAAATTTATCTTGGGCCTTAAAGGTTATGGAAAG
TAAAGCTTTAGAAAATAAAGATAAAGATGTTAAAGAAATAAAGAGTATATTAAGAGAAGAAGCAAAAAGAATTCATGAAG
AAGATATAGAAATATGCAAAACTATAGGGGAAAATCTTATAACTTTATTAAAGGATGGAATGGGAATATTAACTCATTGT
AATGCTGGACAACTTGCTACATCTAAATACGGAACAGCTACATCTCCTATGTATCTTGCAAAGGAAAAGGGCTGGAATTT
TAAAGTTTACTCAGATGAAACTAGACCAAGGCTTCAAGGATCCACTTTAACGGCTTTAGAGTTATATGAAGCAGGAATAG
ATGTAACTACTATAACAGATAATATGGCAGCTATGGTTATGTCTCAAGGTAAAATTGATGCGGTAATAGTAGGATGCGAT
AGAGTAGCAGCTAATGGAGATACTGCTAATAAAATAGGAACCATGGGAGTTTCAATTTTGGCTAAATATTTTGGAATACC
AATGTATATTGCTGCACCAACTCCAAGTATAGATATAAATACAAAAACAGGAGAAGATATACCAATAGAAGAAAGAAATC
CAGAAGAAGTTACTAGTAGATTTGGTGCTTGGACAGCCCCAAAAGGTGTAAAAGTTTATAATCCAGGATTTGATGTTACA
CCACATGAAAACATAACTGCAATTGTTACAGAAAAGGGTATAGTATATCCTCCTTTTAAAGAAAATTTAAAGAAACTTTT
TGAAAAATAA

Upstream 100 bases:

>100_bases
CTTAAAAATAACTGTTTTATATAATAAGATTTCCAAATAAAAAAGGATTAGTAAAGAAGAAATAAGGTAAATAAGATAAA
AGTAAAGAGGAGGATTAAAA

Downstream 100 bases:

>100_bases
GAGGTTAGAAAGGGGCTAAAATAATGGTAGAACTTCTTAATATAAAAAATATAAAAAAGTCCTTTTCAGATGTTCAAGTA
TTACATGAAATAAATAATTG

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFENFFKY
LKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKTIGENLITLLKDGMGILTHC
NAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
RVAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGEDIPIEERNPEEVTSRFGAWTAPKGVKVYNPGFDVT
PHENITAIVTEKGIVYPPFKENLKKLFEK

Sequences:

>Translated_349_residues
MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFENFFKY
LKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKTIGENLITLLKDGMGILTHC
NAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
RVAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGEDIPIEERNPEEVTSRFGAWTAPKGVKVYNPGFDVT
PHENITAIVTEKGIVYPPFKENLKKLFEK
>Mature_348_residues
AELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFENFFKYL
KEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKTIGENLITLLKDGMGILTHCN
AGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCDR
VAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGEDIPIEERNPEEVTSRFGAWTAPKGVKVYNPGFDVTP
HENITAIVTEKGIVYPPFKENLKKLFEK

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=347, Percent_Identity=37.463976945245, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI23943880, Length=336, Percent_Identity=35.1190476190476, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI78000156, Length=276, Percent_Identity=22.463768115942, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI78000158, Length=276, Percent_Identity=22.463768115942, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17557462, Length=327, Percent_Identity=36.3914373088685, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17557123, Length=273, Percent_Identity=26.007326007326, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325375, Length=381, Percent_Identity=36.2204724409449, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322878, Length=159, Percent_Identity=31.4465408805031, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21357667, Length=366, Percent_Identity=37.9781420765027, Blast_Score=218, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24651647, Length=366, Percent_Identity=37.9781420765027, Blast_Score=218, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38703; Mature: 38572

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAY
CCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
GLYFAAKVAPEDNFENFFKYLKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEI
HHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
KSILREEAKRIHEEDIEICKTIGENLITLLKDGMGILTHCNAGQLATSKYGTATSPMYLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCEEEE
KEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
ECCCCEEEEECCCCCCCCCCCEEHHHHHHHCCCCEEEECCHHHHHHHCCCCEEEEEEECC
RVAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGEDIPIEERNPEEVTSR
EEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHH
FGAWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFKENLKKLFEK
HCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCEECCCHHHHHHHHHCC
>Mature Secondary Structure 
AELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAY
CCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
GLYFAAKVAPEDNFENFFKYLKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEI
HHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
KSILREEAKRIHEEDIEICKTIGENLITLLKDGMGILTHCNAGQLATSKYGTATSPMYLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCEEEE
KEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
ECCCCEEEEECCCCCCCCCCCEEHHHHHHHCCCCEEEECCHHHHHHHCCCCEEEEEEECC
RVAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGEDIPIEERNPEEVTSR
EEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHH
FGAWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFKENLKKLFEK
HCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA