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The map label for this gene is moaA

Identifier: 170755099

GI number: 170755099

Start: 2074269

End: 2075228

Strand: Reverse

Name: moaA

Synonym: CLD_2684

Alternate gene names: 170755099

Gene position: 2075228-2074269 (Counterclockwise)

Preceding gene: 170756079

Following gene: 170757754

Centisome position: 52.43

GC content: 28.54

Gene sequence:

>960_bases
ATGTTAGATAAGCATGGAAGGAAAATTAACTATTTAAGAGTATCTGTAACAGATAGATGCAATTTAAGATGTGTTTATTG
TATGCCACCTGAAGGTATTGTAAAAAAAGAACATGATAATATAATGAGATATGAAGAGATATTTAAGGTGGTTAAGTCAG
CTAGTTTATTAGGGGTAAATAAAATTAGATTTACAGGTGGAGAACCTCTTATACTTAAAGATATAGATAAATTAATTTAT
AATACATCAAAAATAAATTCCATTAAAGACATTGCCATGACTACTAATGCTATACTTTTAGAAGATATGGTAGAGGAATT
AAAAAAGGATGGTCTTAAAAGAGTTAATATAAGTCTTGATTCCTTAAAGGAAGACAGGTTTAAGAGTATTACAAGAGGTG
GGGATATTAATAAAGTTTTTAAAAGCATTGAAAAATCTTTATCCATTGGTATGAAACCAATAAAAATTAATACAGTAATA
ATGAAGGGCATAAATGATGATGAAATAGATGATTTTATGAATTTAACAAAGAAATATCCCATATCTGTAAGATTTATAGA
GCTTATGCCTATAGGAGAAGGTAGAAAATTATACGAAGATAGTTATATAAGTTCAGAAGAAATAATATCCAAGCATAGTG
ACCTTATACCTGTGGAAACTGATAAAAGTAGTACTGCTCTATTATATAAATTTAAAGAGTCCAAAGAAAATATTGGGTTT
ATAAGTCCTATGAGTTGTAAATTTTGCAGTGGCTGTAATAGAGTAAGATTAACTTCAGAGGGCACATTGAAACCTTGCCT
TCATTCTGAAAAGGAAGTAGATCTTAAAAACTATGTGGATAGTAGCCAAGCACTTTTGTCTAAGATAAATGAAACTATTT
ATAATAAACCATTAGAGCATCATATGATAGAGGAAAAAGAAAGTAAAAGCAAAAAAATGATGTATCAGATTGGAGGTTAG

Upstream 100 bases:

>100_bases
GGTTATGACTATAGTGAAGCAGGTAATATTGTTTTTATATAAGAAATGATAGATATGTTTCATATACTAAAGAGTAAGCT
TTATATAAAGGAGGGGTTTG

Downstream 100 bases:

>100_bases
CTTATGAATTTAACACATATAAATAAACAAGGAAGAGCAAAAATGGTGGATGTAGGCAGTAAAGGAGATACAGAAAGGGA
AGCTATTGCCTATGGATATG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MLDKHGRKINYLRVSVTDRCNLRCVYCMPPEGIVKKEHDNIMRYEEIFKVVKSASLLGVNKIRFTGGEPLILKDIDKLIY
NTSKINSIKDIAMTTNAILLEDMVEELKKDGLKRVNISLDSLKEDRFKSITRGGDINKVFKSIEKSLSIGMKPIKINTVI
MKGINDDEIDDFMNLTKKYPISVRFIELMPIGEGRKLYEDSYISSEEIISKHSDLIPVETDKSSTALLYKFKESKENIGF
ISPMSCKFCSGCNRVRLTSEGTLKPCLHSEKEVDLKNYVDSSQALLSKINETIYNKPLEHHMIEEKESKSKKMMYQIGG

Sequences:

>Translated_319_residues
MLDKHGRKINYLRVSVTDRCNLRCVYCMPPEGIVKKEHDNIMRYEEIFKVVKSASLLGVNKIRFTGGEPLILKDIDKLIY
NTSKINSIKDIAMTTNAILLEDMVEELKKDGLKRVNISLDSLKEDRFKSITRGGDINKVFKSIEKSLSIGMKPIKINTVI
MKGINDDEIDDFMNLTKKYPISVRFIELMPIGEGRKLYEDSYISSEEIISKHSDLIPVETDKSSTALLYKFKESKENIGF
ISPMSCKFCSGCNRVRLTSEGTLKPCLHSEKEVDLKNYVDSSQALLSKINETIYNKPLEHHMIEEKESKSKKMMYQIGG
>Mature_319_residues
MLDKHGRKINYLRVSVTDRCNLRCVYCMPPEGIVKKEHDNIMRYEEIFKVVKSASLLGVNKIRFTGGEPLILKDIDKLIY
NTSKINSIKDIAMTTNAILLEDMVEELKKDGLKRVNISLDSLKEDRFKSITRGGDINKVFKSIEKSLSIGMKPIKINTVI
MKGINDDEIDDFMNLTKKYPISVRFIELMPIGEGRKLYEDSYISSEEIISKHSDLIPVETDKSSTALLYKFKESKENIGF
ISPMSCKFCSGCNRVRLTSEGTLKPCLHSEKEVDLKNYVDSSQALLSKINETIYNKPLEHHMIEEKESKSKKMMYQIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI22027536, Length=326, Percent_Identity=37.4233128834356, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI116734668, Length=326, Percent_Identity=37.4233128834356, Blast_Score=230, Evalue=1e-60,
Organism=Escherichia coli, GI1786999, Length=329, Percent_Identity=32.8267477203647, Blast_Score=205, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI32566329, Length=328, Percent_Identity=38.109756097561, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI32566331, Length=318, Percent_Identity=38.3647798742138, Blast_Score=227, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17561210, Length=328, Percent_Identity=38.4146341463415, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI28574488, Length=327, Percent_Identity=35.1681957186544, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI28574490, Length=308, Percent_Identity=36.038961038961, Blast_Score=209, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 36468; Mature: 36468

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKHGRKINYLRVSVTDRCNLRCVYCMPPEGIVKKEHDNIMRYEEIFKVVKSASLLGVN
CCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
KIRFTGGEPLILKDIDKLIYNTSKINSIKDIAMTTNAILLEDMVEELKKDGLKRVNISLD
EEEECCCCEEHHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHH
SLKEDRFKSITRGGDINKVFKSIEKSLSIGMKPIKINTVIMKGINDDEIDDFMNLTKKYP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCC
ISVRFIELMPIGEGRKLYEDSYISSEEIISKHSDLIPVETDKSSTALLYKFKESKENIGF
CEEEEEEEEECCCCCHHHHHCCCCHHHHHHHCCCCCEEECCCCCEEEEEEEECCCCCCCC
ISPMSCKFCSGCNRVRLTSEGTLKPCLHSEKEVDLKNYVDSSQALLSKINETIYNKPLEH
CCCCCCHHHCCCCEEEECCCCCCCHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCHHH
HMIEEKESKSKKMMYQIGG
HHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MLDKHGRKINYLRVSVTDRCNLRCVYCMPPEGIVKKEHDNIMRYEEIFKVVKSASLLGVN
CCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
KIRFTGGEPLILKDIDKLIYNTSKINSIKDIAMTTNAILLEDMVEELKKDGLKRVNISLD
EEEECCCCEEHHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHH
SLKEDRFKSITRGGDINKVFKSIEKSLSIGMKPIKINTVIMKGINDDEIDDFMNLTKKYP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCC
ISVRFIELMPIGEGRKLYEDSYISSEEIISKHSDLIPVETDKSSTALLYKFKESKENIGF
CEEEEEEEEECCCCCHHHHHCCCCHHHHHHHCCCCCEEECCCCCEEEEEEEECCCCCCCC
ISPMSCKFCSGCNRVRLTSEGTLKPCLHSEKEVDLKNYVDSSQALLSKINETIYNKPLEH
CCCCCCHHHCCCCEEEECCCCCCCHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCHHH
HMIEEKESKSKKMMYQIGG
HHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA