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The map label for this gene is cobB

Identifier: 170755038

GI number: 170755038

Start: 1044615

End: 1045937

Strand: Direct

Name: cobB

Synonym: CLD_3635

Alternate gene names: 170755038

Gene position: 1044615-1045937 (Clockwise)

Preceding gene: 170756617

Following gene: 170754657

Centisome position: 26.39

GC content: 26.46

Gene sequence:

>1323_bases
ATGAGAAGTATAATAATATCTTCCAATAGTAGTGATGGAGGAAAAACTACAGTAACTTTAGGTCTTATGAAGGCTTTAAT
TAAAAAAGGTTATAAAGTTCAAGGATATAAAGTTGGTCCTGATTATATAGATCCTGCCTTTCATTCTTATGTAACAGAAA
ATAGTTCTAGAAATTTAGATTTATTTTTAATGGGAGAAGATGGTGTTAAAGCATCCTATAGCAGAGGTAAAGGTGATTTA
GGTATAATAGAAGGAGTAATGGGATTATATGATGGTAAAGGAATAGATACAAAATATTCTACAGCCCATTTAGCAAAGGT
TTTAAATTTACCAGTAGTTTTAGTATTAACTCCAAAGGCTCAAAGTGCTACTTTATGTGCAGAAATTATGGGAATATTAA
ATTATGAAAAGATAAGTATAGTTGGAGTAATTTTTAATAAAGTAAGTGAAAACTATTATAAATTACTTAAGAGATTAGTT
GAAGAAAATTGTGGATTAAAAGTATTTGGATATGTACCAAAGAAAGAAAAATTAGAATTGAAAAGTAGACATTTAGGTCT
TATACAAAGTAGTGAAATAAAAGATTTAGAAGAAAAAATAGATTTATGTAGTGAATTAATTTTAAAATATGTAGATATAG
AAAATTTAATAAATCACTTTAAAAAAACAGAAAAATATAAAGATAATTTTTACTTAGAAAACAGAAATCTAAATATAGGC
ATACCTTACGATAAAGCTTTTAGTTTTTATTATAAAGAGAATATAGAACTATTGGAAAACATAGGTAATATAAAATATTT
TAGTCCTATGAAAGATGAAAAATTGCCAGAGTATTTAGATTTTTTATATATAGGTGGGGGATACCCAGAGGTTTTTGTAA
AGGAATTAAGAGAAAACAAATCTATGCTAAGTAGCATAAATAAAAAATTAAATAATGGACTCCCATGCTATGCGGAATGT
GGAGGACTTATGTATTTAACAGAAGGCATAGAAGATTTAGAGGGAGATTATAAAGAAGCAGTAGGATTTTTAAAAGGTAA
GTGTCATATGACTAAGAAACTTCAAAACTTTGGATATGCTGAAATAGAAGTGGAAAAGGAAAATAAAATATTATCTAAAG
GGTTAAAAATTAATTGTCATGAATTTCATAAATCCTATGTGGATTTAAAAGAGGATAAAATATATGAACTTACTAAAAAT
CTCTATGATGATTCCACAAAAAAATGGAGCTGTGGGTATATAAAAAATAATACGTTGGCAGCATATGCTCATGTACATTT
CTTCGGAAATATGGATTTTGTAAGAAATTTATTTAATAGATAA

Upstream 100 bases:

>100_bases
CTCTGTACTCTGTACTCTGTACTCTGTACTCTGTACTCTGTACTCTGTACTCTGTACTCTGTACTCTGTACTCTGTACTC
TGAATTAAAGAGGTGTTTTT

Downstream 100 bases:

>100_bases
AAAGAAAATTAGAGAGGTAAGGGTATGAAAAATTATATAAAAAAGCCAATGGATATAGAAAAAAGAAGTTTTGAAATAAT
AGAAGAAGAGATGGGTAAGC

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRSIIISSNSSDGGKTTVTLGLMKALIKKGYKVQGYKVGPDYIDPAFHSYVTENSSRNLDLFLMGEDGVKASYSRGKGDL
GIIEGVMGLYDGKGIDTKYSTAHLAKVLNLPVVLVLTPKAQSATLCAEIMGILNYEKISIVGVIFNKVSENYYKLLKRLV
EENCGLKVFGYVPKKEKLELKSRHLGLIQSSEIKDLEEKIDLCSELILKYVDIENLINHFKKTEKYKDNFYLENRNLNIG
IPYDKAFSFYYKENIELLENIGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFVKELRENKSMLSSINKKLNNGLPCYAEC
GGLMYLTEGIEDLEGDYKEAVGFLKGKCHMTKKLQNFGYAEIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKN
LYDDSTKKWSCGYIKNNTLAAYAHVHFFGNMDFVRNLFNR

Sequences:

>Translated_440_residues
MRSIIISSNSSDGGKTTVTLGLMKALIKKGYKVQGYKVGPDYIDPAFHSYVTENSSRNLDLFLMGEDGVKASYSRGKGDL
GIIEGVMGLYDGKGIDTKYSTAHLAKVLNLPVVLVLTPKAQSATLCAEIMGILNYEKISIVGVIFNKVSENYYKLLKRLV
EENCGLKVFGYVPKKEKLELKSRHLGLIQSSEIKDLEEKIDLCSELILKYVDIENLINHFKKTEKYKDNFYLENRNLNIG
IPYDKAFSFYYKENIELLENIGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFVKELRENKSMLSSINKKLNNGLPCYAEC
GGLMYLTEGIEDLEGDYKEAVGFLKGKCHMTKKLQNFGYAEIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKN
LYDDSTKKWSCGYIKNNTLAAYAHVHFFGNMDFVRNLFNR
>Mature_440_residues
MRSIIISSNSSDGGKTTVTLGLMKALIKKGYKVQGYKVGPDYIDPAFHSYVTENSSRNLDLFLMGEDGVKASYSRGKGDL
GIIEGVMGLYDGKGIDTKYSTAHLAKVLNLPVVLVLTPKAQSATLCAEIMGILNYEKISIVGVIFNKVSENYYKLLKRLV
EENCGLKVFGYVPKKEKLELKSRHLGLIQSSEIKDLEEKIDLCSELILKYVDIENLINHFKKTEKYKDNFYLENRNLNIG
IPYDKAFSFYYKENIELLENIGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFVKELRENKSMLSSINKKLNNGLPCYAEC
GGLMYLTEGIEDLEGDYKEAVGFLKGKCHMTKKLQNFGYAEIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKN
LYDDSTKKWSCGYIKNNTLAAYAHVHFFGNMDFVRNLFNR

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 50194; Mature: 50194

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIIISSNSSDGGKTTVTLGLMKALIKKGYKVQGYKVGPDYIDPAFHSYVTENSSRNLD
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCCCCCCEE
LFLMGEDGVKASYSRGKGDLGIIEGVMGLYDGKGIDTKYSTAHLAKVLNLPVVLVLTPKA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCC
QSATLCAEIMGILNYEKISIVGVIFNKVSENYYKLLKRLVEENCGLKVFGYVPKKEKLEL
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
KSRHLGLIQSSEIKDLEEKIDLCSELILKYVDIENLINHFKKTEKYKDNFYLENRNLNIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCEEEE
IPYDKAFSFYYKENIELLENIGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFVKELRENK
CCHHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCHHHHCEEEECCCCHHHHHHHHHHHH
SMLSSINKKLNNGLPCYAECGGLMYLTEGIEDLEGDYKEAVGFLKGKCHMTKKLQNFGYA
HHHHHHHHHHHCCCCCHHHCCCEEEEHHCHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCE
EIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKNLYDDSTKKWSCGYIKNNTLA
EEEEECHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCEEECCCEE
AYAHVHFFGNMDFVRNLFNR
EEEEEEEECCHHHHHHHHCC
>Mature Secondary Structure
MRSIIISSNSSDGGKTTVTLGLMKALIKKGYKVQGYKVGPDYIDPAFHSYVTENSSRNLD
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCCCCCCEE
LFLMGEDGVKASYSRGKGDLGIIEGVMGLYDGKGIDTKYSTAHLAKVLNLPVVLVLTPKA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCC
QSATLCAEIMGILNYEKISIVGVIFNKVSENYYKLLKRLVEENCGLKVFGYVPKKEKLEL
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
KSRHLGLIQSSEIKDLEEKIDLCSELILKYVDIENLINHFKKTEKYKDNFYLENRNLNIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCEEEE
IPYDKAFSFYYKENIELLENIGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFVKELRENK
CCHHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCHHHHCEEEECCCCHHHHHHHHHHHH
SMLSSINKKLNNGLPCYAECGGLMYLTEGIEDLEGDYKEAVGFLKGKCHMTKKLQNFGYA
HHHHHHHHHHHCCCCCHHHCCCEEEEHHCHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCE
EIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKNLYDDSTKKWSCGYIKNNTLA
EEEEECHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCEEECCCEE
AYAHVHFFGNMDFVRNLFNR
EEEEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]