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The map label for this gene is norM [H]

Identifier: 170754949

GI number: 170754949

Start: 3073504

End: 3074856

Strand: Reverse

Name: norM [H]

Synonym: CLD_1702

Alternate gene names: 170754949

Gene position: 3074856-3073504 (Counterclockwise)

Preceding gene: 170757856

Following gene: 170755748

Centisome position: 77.68

GC content: 33.7

Gene sequence:

>1353_bases
ATGAAAGGAAACATTAATTTAAAAGAAGGCAATATTTCCAGCACGCTTATTAAATTAGCATTACCTATTATGGGTACATC
TTTTATACAGATGATGTATAATTTAACAGATATGATGTGGTTAGGTAGACTTAGTACCAAGGCCGTAGCCGGAGCAGGTA
CTGTAGGATATTTTATGTGGTTTGGCACGGCATTAGTTCTGATTTCTTCAATAGGGGTAAGTGTGGGTGTATCTCAAGCT
TATGGAAGAAATGATATGGAAGATGCCAGGGAGTATATTTCCAATGCAATAAAATTAGACATATTTATAGGGCTTATTTA
CTCATTGATTTTACTAGTATTTAGATATAAAATAATAGGATTTTTTAATTTGGGTGATTCTGAGACCATTCAAATGGCAA
TAGATTATTATGTAATTATAGGCTGTGGACTTGTATTTCATTTTATCGGTCCAATTTATTCAGCAACATTTAATGCAGCG
GGAAATAGTTTAACGCCTTTCATAATAAATTCTATAGGATTAGTTACTAATGTGATTTTAGACCCTGTTTTAATCTTTGG
GATTGGACCATTCCCCAAAATGGGTATAAAAGGGGCGGCATTAGCCACCGTAGCTGCCCAGATTGTGATTACTTTAATAT
TTATATTAGCATCAAGAAAAAACAAAGTATTATTTTCCCATTTACATATTTTAAAATTACCAAAGAGGGATTACATTAAG
AGGATATTCAAGTTAGGATTTCCAGCTTTTTTACAATCGGGAGCCCTTATATCCGTATCTATAGTTTTGGTAAAAATATT
AGCTAAATGGGGATCAACACCAGTAGCTGTACAATCTATAGGTTCACAAATAGAGGGCATATCATGGAGGACGTCAGAAG
GGTTTTCCTCTGCAATACAAGCATTTATAGGACAAAATTATGGTGCTAGAGATTATGATAGGGTAGAAAAAGGATATTAT
AAAGGAATTAAAATAGTTGGCATTATAGGAATATTTGCAACCCTCATTCTTATATTTGCTGGGGAGCCAATATTTAAAAT
GTTTACACCTGAGGATGCTACTGCAATAGCTCAAGGAATAGTATATTTAAGAATTTTGGGACTAGCTCAATTTTTTATAG
CTATTGAAATGGCATCGGCAGGAGCATTTAATGGTATAGGTAGAACCCGAATCCCAGCAGCAATGGGAATTATATTAAAT
TTTCTAAGGGTTCCTGGAGCTCTAATATTATCAAGCATGGCATTAGGAATGACAGGGGTATGGTGGAGCATGAGTATTAG
TGCTGTATTAAAAGGACTCATCTTAACATCTCTATTTGTATATATGTTAAAAAAAGGTCTTTATAAGAAATAA

Upstream 100 bases:

>100_bases
CTGTGCAATTTATGCACTGTGATGTTGTAACTATATATATCGGATTTGTCGCAAGTTTTGCTGTATTTTTGCTTGCAGTT
GATAAACAGAGGAGGATTAT

Downstream 100 bases:

>100_bases
CTATCATTTTTGGTGCCAGGCACTAAAAATGATAGTTATTATAAATGACTTACTTTCTTAAAGGCAATTACAGCAATACC
AGTATTTAATATATTTCTTA

Product: mate efflux family protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKGNINLKEGNISSTLIKLALPIMGTSFIQMMYNLTDMMWLGRLSTKAVAGAGTVGYFMWFGTALVLISSIGVSVGVSQA
YGRNDMEDAREYISNAIKLDIFIGLIYSLILLVFRYKIIGFFNLGDSETIQMAIDYYVIIGCGLVFHFIGPIYSATFNAA
GNSLTPFIINSIGLVTNVILDPVLIFGIGPFPKMGIKGAALATVAAQIVITLIFILASRKNKVLFSHLHILKLPKRDYIK
RIFKLGFPAFLQSGALISVSIVLVKILAKWGSTPVAVQSIGSQIEGISWRTSEGFSSAIQAFIGQNYGARDYDRVEKGYY
KGIKIVGIIGIFATLILIFAGEPIFKMFTPEDATAIAQGIVYLRILGLAQFFIAIEMASAGAFNGIGRTRIPAAMGIILN
FLRVPGALILSSMALGMTGVWWSMSISAVLKGLILTSLFVYMLKKGLYKK

Sequences:

>Translated_450_residues
MKGNINLKEGNISSTLIKLALPIMGTSFIQMMYNLTDMMWLGRLSTKAVAGAGTVGYFMWFGTALVLISSIGVSVGVSQA
YGRNDMEDAREYISNAIKLDIFIGLIYSLILLVFRYKIIGFFNLGDSETIQMAIDYYVIIGCGLVFHFIGPIYSATFNAA
GNSLTPFIINSIGLVTNVILDPVLIFGIGPFPKMGIKGAALATVAAQIVITLIFILASRKNKVLFSHLHILKLPKRDYIK
RIFKLGFPAFLQSGALISVSIVLVKILAKWGSTPVAVQSIGSQIEGISWRTSEGFSSAIQAFIGQNYGARDYDRVEKGYY
KGIKIVGIIGIFATLILIFAGEPIFKMFTPEDATAIAQGIVYLRILGLAQFFIAIEMASAGAFNGIGRTRIPAAMGIILN
FLRVPGALILSSMALGMTGVWWSMSISAVLKGLILTSLFVYMLKKGLYKK
>Mature_450_residues
MKGNINLKEGNISSTLIKLALPIMGTSFIQMMYNLTDMMWLGRLSTKAVAGAGTVGYFMWFGTALVLISSIGVSVGVSQA
YGRNDMEDAREYISNAIKLDIFIGLIYSLILLVFRYKIIGFFNLGDSETIQMAIDYYVIIGCGLVFHFIGPIYSATFNAA
GNSLTPFIINSIGLVTNVILDPVLIFGIGPFPKMGIKGAALATVAAQIVITLIFILASRKNKVLFSHLHILKLPKRDYIK
RIFKLGFPAFLQSGALISVSIVLVKILAKWGSTPVAVQSIGSQIEGISWRTSEGFSSAIQAFIGQNYGARDYDRVEKGYY
KGIKIVGIIGIFATLILIFAGEPIFKMFTPEDATAIAQGIVYLRILGLAQFFIAIEMASAGAFNGIGRTRIPAAMGIILN
FLRVPGALILSSMALGMTGVWWSMSISAVLKGLILTSLFVYMLKKGLYKK

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=292, Percent_Identity=26.027397260274, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48912; Mature: 48912

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]