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The map label for this gene is ribB

Identifier: 170754581

GI number: 170754581

Start: 1500620

End: 1501258

Strand: Direct

Name: ribB

Synonym: CLD_3201

Alternate gene names: 170754581

Gene position: 1500620-1501258 (Clockwise)

Preceding gene: 170755381

Following gene: 170757376

Centisome position: 37.91

GC content: 34.9

Gene sequence:

>639_bases
ATGAATGAATCACTATTAACTCAGTTTGGCAATTCTTTAACCCGTGTAGAAAAAGCATTAAATTACTTAAAAGAAGGTAG
CGGAGTACTTCTTGTTGATGATGAAAATCGTGAAAATGAAGGAGATCTTATTTTCCCTGCTGAAACTATTACAATATCTC
AAATGGCTATGTTAATAAGAGAATGCAGTGGTATTGTCTGCCTTTGCTTAACAGATGAAAAAGTAAAAAAAATAGGTTTA
CCCCAAATGGTACCTAATAATACTTGTAAGTACGAAACAGCATTTACTATTTCAATTGAAGCTAAGGAAGGAGTAACTAC
AGGAGTTTCCGCTGCAGATAGAGTTAATACAATTCTTACTGCAATAAAAGATGATTGTGAACCTGAAGATTTATGTCATC
CTGGTCATGTTTTCCCACTTCGTGCTCGTGTAGGAGGTGTTTTAACTAGACCTGGCCATACAGAAGGTACTGTTGATCTT
ATGCGTTTAGCAGGATATAAGCCTGCAGGGATTTTATGTGAACTTACAAATCCTGATGGAACTATGGCTCGGCTACCACA
GATAATCAGTTTTGCTAAAGAACATAATTTAACTGTTCTTTCCATTGAAGATATCATAAACTATAGACAAACTATATAA

Upstream 100 bases:

>100_bases
ATTCTGTCCAAAGATAAATCCACATAAAAGTAATATACATATAATAAAAAAACTGAGGTGCTTTATGTAAAATTTTTTTC
ATAAATTGGAGGAATTTTAA

Downstream 100 bases:

>100_bases
ATTAATATAACAGTCCTTAAAGACATTAAAACCAGAAATACTCTGAGAAAAAATAAATAACTATAAAAATAATTAGAATG
TTTTATTTGTGAACTAGTAT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNESLLTQFGNSLTRVEKALNYLKEGSGVLLVDDENRENEGDLIFPAETITISQMAMLIRECSGIVCLCLTDEKVKKIGL
PQMVPNNTCKYETAFTISIEAKEGVTTGVSAADRVNTILTAIKDDCEPEDLCHPGHVFPLRARVGGVLTRPGHTEGTVDL
MRLAGYKPAGILCELTNPDGTMARLPQIISFAKEHNLTVLSIEDIINYRQTI

Sequences:

>Translated_212_residues
MNESLLTQFGNSLTRVEKALNYLKEGSGVLLVDDENRENEGDLIFPAETITISQMAMLIRECSGIVCLCLTDEKVKKIGL
PQMVPNNTCKYETAFTISIEAKEGVTTGVSAADRVNTILTAIKDDCEPEDLCHPGHVFPLRARVGGVLTRPGHTEGTVDL
MRLAGYKPAGILCELTNPDGTMARLPQIISFAKEHNLTVLSIEDIINYRQTI
>Mature_212_residues
MNESLLTQFGNSLTRVEKALNYLKEGSGVLLVDDENRENEGDLIFPAETITISQMAMLIRECSGIVCLCLTDEKVKKIGL
PQMVPNNTCKYETAFTISIEAKEGVTTGVSAADRVNTILTAIKDDCEPEDLCHPGHVFPLRARVGGVLTRPGHTEGTVDL
MRLAGYKPAGILCELTNPDGTMARLPQIISFAKEHNLTVLSIEDIINYRQTI

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=210, Percent_Identity=63.3333333333333, Blast_Score=293, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=40.1960784313725, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23221; Mature: 23221

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESLLTQFGNSLTRVEKALNYLKEGSGVLLVDDENRENEGDLIFPAETITISQMAMLIR
CCHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHH
ECSGIVCLCLTDEKVKKIGLPQMVPNNTCKYETAFTISIEAKEGVTTGVSAADRVNTILT
HCCCEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AIKDDCEPEDLCHPGHVFPLRARVGGVLTRPGHTEGTVDLMRLAGYKPAGILCELTNPDG
HHHCCCCHHHCCCCCCEEEEHHHHCEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCC
TMARLPQIISFAKEHNLTVLSIEDIINYRQTI
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCC
>Mature Secondary Structure
MNESLLTQFGNSLTRVEKALNYLKEGSGVLLVDDENRENEGDLIFPAETITISQMAMLIR
CCHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHH
ECSGIVCLCLTDEKVKKIGLPQMVPNNTCKYETAFTISIEAKEGVTTGVSAADRVNTILT
HCCCEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AIKDDCEPEDLCHPGHVFPLRARVGGVLTRPGHTEGTVDLMRLAGYKPAGILCELTNPDG
HHHCCCCHHHCCCCCCEEEEHHHHCEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCC
TMARLPQIISFAKEHNLTVLSIEDIINYRQTI
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA