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The map label for this gene is spr [H]

Identifier: 170754497

GI number: 170754497

Start: 1993937

End: 1994692

Strand: Reverse

Name: spr [H]

Synonym: CLD_2769

Alternate gene names: 170754497

Gene position: 1994692-1993937 (Counterclockwise)

Preceding gene: 170757366

Following gene: 170756690

Centisome position: 50.39

GC content: 33.2

Gene sequence:

>756_bases
ATGAAAAAGAAGACAACTATATTAAGTATCTTTCTAGCTGCTTTTATGGCTTTATTACTAAATGTAGGTAATGTTAAAGC
TGCGCCAACTGGACAAGATATAGTAAACTACGCTATGAAGTTTAGAGGGACTCCATATGTTTTGGGGGGAGATGATCCAT
CAGGATTTGATTGTTCAGGATTTGTTCAATATGTATATAAAAATGCGGCAGGAATAAATTTACCAAGAGATACATATGGA
CAAATTAATGTAGGTACATCGGTATTACAAAGTAATTTACAACCAGGAGATTTAGTATTTCCACATACAGGCCATGTAGG
CATATATGTTGGAAATGGACAAATGATACATTCACCGGAATCAGGAGATGTTGTAAAAGTTTCACCTATAGGAAATTTTT
ATGCAGGAAGAAGAATTATAAATACACCACAATCTTATGTTAAAGTAGATGGTGGCGGATATGCTAATTATAATGGCGCT
CCAGGATTAAATTTGATAATTAGAGATTTTAGTTCAGATATTGCAAGAGTATTTGCATGGGTGGATTCAGACACTGGTGC
TTCTTGGTCTTTTGCATTAGATCCACCAAACTCAAATTATACAAAATTATATAAAAATACTAGTAAAGTAATAACAAAGA
GAAATGGAGGATACACTTTCTCTAAAGGGGCTACGTATAAGGTAAAAGTTAAAGGGTACAATAGTTCTGGACAAGTTGTA
GCAGAAAATCAAATAACTCTTAAAATACCTCAATAA

Upstream 100 bases:

>100_bases
AATATGAAGGATAAAAAAAGAAGGAATTCAAATAATTGTAAAGAATATAATGATTATAGGTTGTCATACCAAAATAAACA
CATGAGAAGGGGGAATAAAC

Downstream 100 bases:

>100_bases
AATCTTAATTTCATAAAGGAATTTTTTAACATTTGTAGAATATTAAATATAATGGTTTTCTATAAGTTAAGCAGATACTT
CCCAAAAAACAAAAGAACCC

Product: nlpC/P60 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKKKTTILSIFLAAFMALLLNVGNVKAAPTGQDIVNYAMKFRGTPYVLGGDDPSGFDCSGFVQYVYKNAAGINLPRDTYG
QINVGTSVLQSNLQPGDLVFPHTGHVGIYVGNGQMIHSPESGDVVKVSPIGNFYAGRRIINTPQSYVKVDGGGYANYNGA
PGLNLIIRDFSSDIARVFAWVDSDTGASWSFALDPPNSNYTKLYKNTSKVITKRNGGYTFSKGATYKVKVKGYNSSGQVV
AENQITLKIPQ

Sequences:

>Translated_251_residues
MKKKTTILSIFLAAFMALLLNVGNVKAAPTGQDIVNYAMKFRGTPYVLGGDDPSGFDCSGFVQYVYKNAAGINLPRDTYG
QINVGTSVLQSNLQPGDLVFPHTGHVGIYVGNGQMIHSPESGDVVKVSPIGNFYAGRRIINTPQSYVKVDGGGYANYNGA
PGLNLIIRDFSSDIARVFAWVDSDTGASWSFALDPPNSNYTKLYKNTSKVITKRNGGYTFSKGATYKVKVKGYNSSGQVV
AENQITLKIPQ
>Mature_251_residues
MKKKTTILSIFLAAFMALLLNVGNVKAAPTGQDIVNYAMKFRGTPYVLGGDDPSGFDCSGFVQYVYKNAAGINLPRDTYG
QINVGTSVLQSNLQPGDLVFPHTGHVGIYVGNGQMIHSPESGDVVKVSPIGNFYAGRRIINTPQSYVKVDGGGYANYNGA
PGLNLIIRDFSSDIARVFAWVDSDTGASWSFALDPPNSNYTKLYKNTSKVITKRNGGYTFSKGATYKVKVKGYNSSGQVV
AENQITLKIPQ

Specific function: Unknown

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpC/p60 family [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=139, Percent_Identity=38.8489208633094, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787944, Length=141, Percent_Identity=34.0425531914894, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788001, Length=110, Percent_Identity=41.8181818181818, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786421, Length=113, Percent_Identity=37.1681415929204, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064 [H]

Pfam domain/function: PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 27057; Mature: 27057

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKTTILSIFLAAFMALLLNVGNVKAAPTGQDIVNYAMKFRGTPYVLGGDDPSGFDCSG
CCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
FVQYVYKNAAGINLPRDTYGQINVGTSVLQSNLQPGDLVFPHTGHVGIYVGNGQMIHSPE
HHHHHHHCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEECCCCCCEEEEECCCEEEECCC
SGDVVKVSPIGNFYAGRRIINTPQSYVKVDGGGYANYNGAPGLNLIIRDFSSDIARVFAW
CCCEEEEECCCCHHHCCEEECCCCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHEEHEEE
VDSDTGASWSFALDPPNSNYTKLYKNTSKVITKRNGGYTFSKGATYKVKVKGYNSSGQVV
EECCCCCEEEEEECCCCCCHHEEECCCCCEEEECCCCEEECCCCEEEEEEEEECCCCCEE
AENQITLKIPQ
ECCEEEEEECC
>Mature Secondary Structure
MKKKTTILSIFLAAFMALLLNVGNVKAAPTGQDIVNYAMKFRGTPYVLGGDDPSGFDCSG
CCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
FVQYVYKNAAGINLPRDTYGQINVGTSVLQSNLQPGDLVFPHTGHVGIYVGNGQMIHSPE
HHHHHHHCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEECCCCCCEEEEECCCEEEECCC
SGDVVKVSPIGNFYAGRRIINTPQSYVKVDGGGYANYNGAPGLNLIIRDFSSDIARVFAW
CCCEEEEECCCCHHHCCEEECCCCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHEEHEEE
VDSDTGASWSFALDPPNSNYTKLYKNTSKVITKRNGGYTFSKGATYKVKVKGYNSSGQVV
EECCCCCEEEEEECCCCCCHHEEECCCCCEEEECCCCEEECCCCEEEEEEEEECCCCCEE
AENQITLKIPQ
ECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]