| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
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The map label for this gene is aceE [H]
Identifier: 170751981
GI number: 170751981
Start: 5943940
End: 5946615
Strand: Reverse
Name: aceE [H]
Synonym: Mrad2831_5613
Alternate gene names: 170751981
Gene position: 5946615-5943940 (Counterclockwise)
Preceding gene: 170751983
Following gene: 170751980
Centisome position: 97.84
GC content: 71.11
Gene sequence:
>2676_bases ATGAACGCCATACCGCCGAAAGCCACGATCGCGCGGTCCGCCGAGGTGGATCACGACCCGGCCGAGACCCAGGACTGGCT CGCCGCGCTGGAATCCGTCTTCCGCACCGAGGGCGCGGCCCGGGCCCGGTTCATCCTCGACCGCCTGGAGCGGCGCTCGA AGGAGATCGGCATCCTCGACGAGGCCCTGCCCTACTCGCCCTACCGGAACACGATCGCGCTGGAGAAGCAGCCGCGCTAC CCCGGCGACCTCGACATCGAGGAGCGCCTGACCTCGATCATGCGCTGGAACGCCCTCGCCATGGTGGTGCGCGCCAATAT GGCCTACGGCGAGCTCGGCGGCCACGTGGCGAGCTACGCCTCGGCGGCGGAGCTGTTCGAGGTCGGGTTCAACCACTTCT TCAAGGGCGGCACGGACGGCGACCTCGTCTATTTCCAGCCGCACTCGGCGCCGGGCGTCTACGCCCGGGCCTTCCTCGAG GGCCGGCTCTCCGAGGAGCAGCTGAAGCACTACCGCCAGGAGATCGCCGGCGACGGGCTGTGCTCCTACCCGCATCCCTG GCTGATGCCGGATTTCTGGCAGGTCCCCACCGGCTCGATGGGCATCGGGCCGATCCACGCGGTCTACCAGGCGCGATTCA TGCGCTACCTCGGCGACCGGGGCCTCGCCGACACCGCCGGCCGCCACGTCTGGGGCGTGTTCGGCGACGGCGAGATGGAC GAGCCCGAGTCGATCGGCGGCCTCGCGTTGGCGGCACGCGAGAATCTCGACAACCTGACCTTCGTCATCAACTGCAACCT GCAGCGGCTCGACGGGCCGGTGCGCGGCAACGGCCAGATCATCCAGGAGCTGGAGAGCCTGTTCCGCGGCGCCGGCTGGA ACGTCATCAAGGTGCTGTGGGGCTCGGAGTGGGACGGGATCTTCGCCCGCGACACCAACCACGCCCTGCTGCGCCGCTTC GCCGAGACGGTGGACGGCAAGTACCAGACGCTCGGCGCCAAGGACGGCGCCTACAACCTCGCGCACTTCTTCGGCGAGGA CCCGGAGGTGCGCGAGCTCGTCGCCCACATGTCGGACGCCGACGTCGACCGGCTGAAGCGCGGCGGCCACGACTTCCGCA AGCTCTACGCGGCCTTCGCGGCCGCCAAGGCCACCAAGGGCCGGCCGACGGTGATCCTGGCCAAGACCAAGAAGGGCTAC GGCATGGGCGGCGCGGGCGAGTCGCGCATGACCGCCCACCAGGCCAAGAAGCTCGACGTCGACGCGCTGCGGGCGTTCCG CGACCGGTTCGCCCTGCCGCTGTCGGATGCCCAGGTGGAAGGTCTCGCCTTCTACAAGCCGGCCGAGGACGGCGCCGAGA TGCGCTACCTGCGCGAGCGCCGGGAGACACTCGGCGGCGTCCTGCCGGCTCGCCGCCGCACCGCGCCGACCGTCGCGGTT CCGGCGCTCTCCACTTACGCGGGCTTCGCCCTGGAGGCCGGCGGCAAGGAGATGTCGACGACCACGGCGGTGGTGCGCCT GTTCGGCAACCTCCTGAAGCACAAGGATCTCGGGCCGCGCATCGTGCCGATCGTCGCCGACGAGGCGCGGACCTTCGGCA TGGCCAACCTGTTCCGGCAGGTCGGGATTTACGCGCCGCAGGGGCAGCTCTACGAGCCGGAGGATGCCGGCTCCATGCTC TACTACCGCGAGGCCCGGGACGGGCAGCTATTGGAGGAGGGCATCACCGAGGCCGGGGCGATCTCGTCCTGGACCGCGGC GGCCACGTCCTACAGCGTCCACGGCCTGTCGATGCTGCCGTTCTACATCTACTACTCGATGTTCGGCTTCCAGCGGGTCG GCGACCTGATCTGGGCGGCGGCCGACCAGCGGGCCCGCGGCTTCCTGATCGGCGCCACGGCGGGCCGCACGACGCTCGGC GGCGAGGGCCTGCAGCATCAGGACGGATCGAGCCACATGCAGGCCGCCGCGATCCCGAACTGCCGGGCCTACGATCCGGC CTTCGCGTACGAGATGGCGGTGATCGTCGACCGGGGGGCCCGGGCGATGATGGAGGAGGGCGAGGACGCTTTCTACTACC TCACCGCGATGAACGAGAACTACGCCCAGCCCTCCATGCCGCAGGGAGCGGAGGCCGGGATCCTGAAGGGCATGTACCGC CTGTCGGGGCCTGAGGCGGGAAGCGCCGCCGTGCGCCTCCTCGGCTCCGGAGCGATCCTGCCGGAGGTGATCGCGGCGGC GGCGCTGCTCGCGCAGGATTTCGGCGTCGCGGCCGAGGTGTTCAGCGTGACGAGCTTCAGCGAGCTGGCCCGCGATGCCC GCGAGGCCGAGCGGCAGGCGATGCTCAACCCGGAGGCCGAGGCGCCGGTCAGCCACGTGGCGGCGCTGCTGCCGGGCCCG GCGCCCGTCGTCGCGGCGAGCGACTACGTCCGGGCCTACCCGCAGCTGATCGCCTCCTATGTCGGCGCGCGATTCGTCGC CCTCGGCACCGACGGGTTCGGGCGGAGCGACACCCGCAACGCGCTCCGCCGCTTCTTCGAGGTCGACCGGCAGCACGTCG TCGTCGCCGCCCTGCACGCCCTCGCCGAGGCCGGCACGGTGCCGCGTGCGACGGTGGCGGACGCGATCCGCCGCTACAGC ATCGCGGCGGACGCGCCCGCGCCCTGGACGATCTGA
Upstream 100 bases:
>100_bases GCGAAATATCAATCCGCGCAACGCGGAAACACAGCAAATAATCGGCATGTCCCGCCGCGGCGATCCCCGTATGATCGCGC TGAACAGGGAGGCCGCGCCG
Downstream 100 bases:
>100_bases GGCCGGGCGCCCCGCCGAGGGGCGCCGCCCGTCCCACCCCTTCTCCGAACGCCCGACCTACGGACATCCGACCGCATGAG CGCCGCGCTGCAGATCGCCC
Product: 2-oxoacid dehydrogenase subunit E1
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 891; Mature: 891
Protein sequence:
>891_residues MNAIPPKATIARSAEVDHDPAETQDWLAALESVFRTEGAARARFILDRLERRSKEIGILDEALPYSPYRNTIALEKQPRY PGDLDIEERLTSIMRWNALAMVVRANMAYGELGGHVASYASAAELFEVGFNHFFKGGTDGDLVYFQPHSAPGVYARAFLE GRLSEEQLKHYRQEIAGDGLCSYPHPWLMPDFWQVPTGSMGIGPIHAVYQARFMRYLGDRGLADTAGRHVWGVFGDGEMD EPESIGGLALAARENLDNLTFVINCNLQRLDGPVRGNGQIIQELESLFRGAGWNVIKVLWGSEWDGIFARDTNHALLRRF AETVDGKYQTLGAKDGAYNLAHFFGEDPEVRELVAHMSDADVDRLKRGGHDFRKLYAAFAAAKATKGRPTVILAKTKKGY GMGGAGESRMTAHQAKKLDVDALRAFRDRFALPLSDAQVEGLAFYKPAEDGAEMRYLRERRETLGGVLPARRRTAPTVAV PALSTYAGFALEAGGKEMSTTTAVVRLFGNLLKHKDLGPRIVPIVADEARTFGMANLFRQVGIYAPQGQLYEPEDAGSML YYREARDGQLLEEGITEAGAISSWTAAATSYSVHGLSMLPFYIYYSMFGFQRVGDLIWAAADQRARGFLIGATAGRTTLG GEGLQHQDGSSHMQAAAIPNCRAYDPAFAYEMAVIVDRGARAMMEEGEDAFYYLTAMNENYAQPSMPQGAEAGILKGMYR LSGPEAGSAAVRLLGSGAILPEVIAAAALLAQDFGVAAEVFSVTSFSELARDAREAERQAMLNPEAEAPVSHVAALLPGP APVVAASDYVRAYPQLIASYVGARFVALGTDGFGRSDTRNALRRFFEVDRQHVVVAALHALAEAGTVPRATVADAIRRYS IAADAPAPWTI
Sequences:
>Translated_891_residues MNAIPPKATIARSAEVDHDPAETQDWLAALESVFRTEGAARARFILDRLERRSKEIGILDEALPYSPYRNTIALEKQPRY PGDLDIEERLTSIMRWNALAMVVRANMAYGELGGHVASYASAAELFEVGFNHFFKGGTDGDLVYFQPHSAPGVYARAFLE GRLSEEQLKHYRQEIAGDGLCSYPHPWLMPDFWQVPTGSMGIGPIHAVYQARFMRYLGDRGLADTAGRHVWGVFGDGEMD EPESIGGLALAARENLDNLTFVINCNLQRLDGPVRGNGQIIQELESLFRGAGWNVIKVLWGSEWDGIFARDTNHALLRRF AETVDGKYQTLGAKDGAYNLAHFFGEDPEVRELVAHMSDADVDRLKRGGHDFRKLYAAFAAAKATKGRPTVILAKTKKGY GMGGAGESRMTAHQAKKLDVDALRAFRDRFALPLSDAQVEGLAFYKPAEDGAEMRYLRERRETLGGVLPARRRTAPTVAV PALSTYAGFALEAGGKEMSTTTAVVRLFGNLLKHKDLGPRIVPIVADEARTFGMANLFRQVGIYAPQGQLYEPEDAGSML YYREARDGQLLEEGITEAGAISSWTAAATSYSVHGLSMLPFYIYYSMFGFQRVGDLIWAAADQRARGFLIGATAGRTTLG GEGLQHQDGSSHMQAAAIPNCRAYDPAFAYEMAVIVDRGARAMMEEGEDAFYYLTAMNENYAQPSMPQGAEAGILKGMYR LSGPEAGSAAVRLLGSGAILPEVIAAAALLAQDFGVAAEVFSVTSFSELARDAREAERQAMLNPEAEAPVSHVAALLPGP APVVAASDYVRAYPQLIASYVGARFVALGTDGFGRSDTRNALRRFFEVDRQHVVVAALHALAEAGTVPRATVADAIRRYS IAADAPAPWTI >Mature_891_residues MNAIPPKATIARSAEVDHDPAETQDWLAALESVFRTEGAARARFILDRLERRSKEIGILDEALPYSPYRNTIALEKQPRY PGDLDIEERLTSIMRWNALAMVVRANMAYGELGGHVASYASAAELFEVGFNHFFKGGTDGDLVYFQPHSAPGVYARAFLE GRLSEEQLKHYRQEIAGDGLCSYPHPWLMPDFWQVPTGSMGIGPIHAVYQARFMRYLGDRGLADTAGRHVWGVFGDGEMD EPESIGGLALAARENLDNLTFVINCNLQRLDGPVRGNGQIIQELESLFRGAGWNVIKVLWGSEWDGIFARDTNHALLRRF AETVDGKYQTLGAKDGAYNLAHFFGEDPEVRELVAHMSDADVDRLKRGGHDFRKLYAAFAAAKATKGRPTVILAKTKKGY GMGGAGESRMTAHQAKKLDVDALRAFRDRFALPLSDAQVEGLAFYKPAEDGAEMRYLRERRETLGGVLPARRRTAPTVAV PALSTYAGFALEAGGKEMSTTTAVVRLFGNLLKHKDLGPRIVPIVADEARTFGMANLFRQVGIYAPQGQLYEPEDAGSML YYREARDGQLLEEGITEAGAISSWTAAATSYSVHGLSMLPFYIYYSMFGFQRVGDLIWAAADQRARGFLIGATAGRTTLG GEGLQHQDGSSHMQAAAIPNCRAYDPAFAYEMAVIVDRGARAMMEEGEDAFYYLTAMNENYAQPSMPQGAEAGILKGMYR LSGPEAGSAAVRLLGSGAILPEVIAAAALLAQDFGVAAEVFSVTSFSELARDAREAERQAMLNPEAEAPVSHVAALLPGP APVVAASDYVRAYPQLIASYVGARFVALGTDGFGRSDTRNALRRFFEVDRQHVVVAALHALAEAGTVPRATVADAIRRYS IAADAPAPWTI
Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge
COG id: COG2609
COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1786304, Length=879, Percent_Identity=54.835039817975, Blast_Score=981, Evalue=0.0,
Paralogues:
None
Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004660 - InterPro: IPR009014 - InterPro: IPR015941 - InterPro: IPR005474 [H]
Pfam domain/function: PF00456 Transketolase_N [H]
EC number: =1.2.4.1 [H]
Molecular weight: Translated: 97079; Mature: 97079
Theoretical pI: Translated: 5.94; Mature: 5.94
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNAIPPKATIARSAEVDHDPAETQDWLAALESVFRTEGAARARFILDRLERRSKEIGILD CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH EALPYSPYRNTIALEKQPRYPGDLDIEERLTSIMRWNALAMVVRANMAYGELGGHVASYA HCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH SAAELFEVGFNHFFKGGTDGDLVYFQPHSAPGVYARAFLEGRLSEEQLKHYRQEIAGDGL HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC CSYPHPWLMPDFWQVPTGSMGIGPIHAVYQARFMRYLGDRGLADTAGRHVWGVFGDGEMD CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC EPESIGGLALAARENLDNLTFVINCNLQRLDGPVRGNGQIIQELESLFRGAGWNVIKVLW CCCCCCCEEEEHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE GSEWDGIFARDTNHALLRRFAETVDGKYQTLGAKDGAYNLAHFFGEDPEVRELVAHMSDA CCCCCCEEECCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCHHHHHHHHHCCCC DVDRLKRGGHDFRKLYAAFAAAKATKGRPTVILAKTKKGYGMGGAGESRMTAHQAKKLDV CHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCH DALRAFRDRFALPLSDAQVEGLAFYKPAEDGAEMRYLRERRETLGGVLPARRRTAPTVAV HHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEC PALSTYAGFALEAGGKEMSTTTAVVRLFGNLLKHKDLGPRIVPIVADEARTFGMANLFRQ CCHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHH VGIYAPQGQLYEPEDAGSMLYYREARDGQLLEEGITEAGAISSWTAAATSYSVHGLSMLP HCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCHHCCCCCCHHHHHHCCCCCCHHHHH FYIYYSMFGFQRVGDLIWAAADQRARGFLIGATAGRTTLGGEGLQHQDGSSHMQAAAIPN HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCC CRAYDPAFAYEMAVIVDRGARAMMEEGEDAFYYLTAMNENYAQPSMPQGAEAGILKGMYR CCCCCCHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH LSGPEAGSAAVRLLGSGAILPEVIAAAALLAQDFGVAAEVFSVTSFSELARDAREAERQA HCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH MLNPEAEAPVSHVAALLPGPAPVVAASDYVRAYPQLIASYVGARFVALGTDGFGRSDTRN HCCCCCCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHH ALRRFFEVDRQHVVVAALHALAEAGTVPRATVADAIRRYSIAADAPAPWTI HHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC >Mature Secondary Structure MNAIPPKATIARSAEVDHDPAETQDWLAALESVFRTEGAARARFILDRLERRSKEIGILD CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH EALPYSPYRNTIALEKQPRYPGDLDIEERLTSIMRWNALAMVVRANMAYGELGGHVASYA HCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH SAAELFEVGFNHFFKGGTDGDLVYFQPHSAPGVYARAFLEGRLSEEQLKHYRQEIAGDGL HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC CSYPHPWLMPDFWQVPTGSMGIGPIHAVYQARFMRYLGDRGLADTAGRHVWGVFGDGEMD CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC EPESIGGLALAARENLDNLTFVINCNLQRLDGPVRGNGQIIQELESLFRGAGWNVIKVLW CCCCCCCEEEEHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE GSEWDGIFARDTNHALLRRFAETVDGKYQTLGAKDGAYNLAHFFGEDPEVRELVAHMSDA CCCCCCEEECCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCHHHHHHHHHCCCC DVDRLKRGGHDFRKLYAAFAAAKATKGRPTVILAKTKKGYGMGGAGESRMTAHQAKKLDV CHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCH DALRAFRDRFALPLSDAQVEGLAFYKPAEDGAEMRYLRERRETLGGVLPARRRTAPTVAV HHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEC PALSTYAGFALEAGGKEMSTTTAVVRLFGNLLKHKDLGPRIVPIVADEARTFGMANLFRQ CCHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHH VGIYAPQGQLYEPEDAGSMLYYREARDGQLLEEGITEAGAISSWTAAATSYSVHGLSMLP HCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCHHCCCCCCHHHHHHCCCCCCHHHHH FYIYYSMFGFQRVGDLIWAAADQRARGFLIGATAGRTTLGGEGLQHQDGSSHMQAAAIPN HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCC CRAYDPAFAYEMAVIVDRGARAMMEEGEDAFYYLTAMNENYAQPSMPQGAEAGILKGMYR CCCCCCHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH LSGPEAGSAAVRLLGSGAILPEVIAAAALLAQDFGVAAEVFSVTSFSELARDAREAERQA HCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH MLNPEAEAPVSHVAALLPGPAPVVAASDYVRAYPQLIASYVGARFVALGTDGFGRSDTRN HCCCCCCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHH ALRRFFEVDRQHVVVAALHALAEAGTVPRATVADAIRRYSIAADAPAPWTI HHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9171401; 10984043 [H]