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The map label for this gene is flhA [H]

Identifier: 170751945

GI number: 170751945

Start: 5896974

End: 5899121

Strand: Reverse

Name: flhA [H]

Synonym: Mrad2831_5577

Alternate gene names: 170751945

Gene position: 5899121-5896974 (Counterclockwise)

Preceding gene: 170751947

Following gene: 170751941

Centisome position: 97.06

GC content: 69.18

Gene sequence:

>2148_bases
ATGGCAGAGACGGCGAGCGCGCCGGCACAGACAGGGGCGGCGGCCGTCCTCGGCCAGCTGACGCTGCCGACGCGCGGCGA
CCTCCAGGCACTGTCGAAGCGGTCGGACCTCCTCTTTGCCACCGGCGTGCTGGGGATCCTGGCGGTCCTCATCTTCCCGC
TGCCGGCGATCCTGCTCGACCTGCTGCTGGCCGTGTCGATCATCATGTCGGTCCTGATCATGATGACCGGCCTGTCGATC
GACAATCCGCTGGAATTCACCGTCTTCCCGACGCTGCTGCTCATCGCCACGATGCTGCGGCTCGCCCTGAACCTCGCCTC
GACGCGCCTCATCCTCGGCCACGGCCACGAGGGCACGGCGGCGGCCGGCCACGTCATCGAGGCCTTCGGCCACTTCGTGA
TGGGGGGCAACTTCGTCATCGGGATCATCGTGTTCGCGATCCTGATCATCGTGAATTTCGTGGTCATCACGAAGGGCTCG
GGCCGGATCGCCGAGGTCGCGGCCCGCTTCACCCTCGACGCGATGCCCGGCAAGCAGATGGCGATCGACGCCGACCTGTC
GGCCGGCCTGATCGACGAGAAGGCCGCGAAGGCTCGGCGCGCGGCCCTGGAGGAGGAGTCCTCCTTCTTCGGCGCCATGG
ACGGTGCCTCGAAATTCGTGCGCGGCGACGCGGTGGCGGCCCTGCTGATCACCTTCATCAACGTGGTCGGCGGCATCATC
ATCGGCGTGGCGCAGCAGGGCCTGAGCTTCGGGGAGGCCGCCAAGAGCTACACCCTGCTGACCATCGGCGACGGCCTGGC
AAGCCAGGTCCCCGCGCTGATCGTGTCGACGGCGGCGGGCCTGCTGGTCTCGAAGGCCGGCGTGCGCGGAGCCGCCGACA
AGGCGCTCGGCAAGCAGCTCGCGCATTATCCCAAGGCGCTGGGCATGTCGGCGGCGGTGATGCTGCTGATCGCCCTCCTG
CCCGGCATGCCGATGCTGCCCTTCGTCCTGCTGGGCGGCGGGGCCGGCTACGCGGCGTGGCGCATCAACAAGACCGCCAA
GCTGGCGCCGCCCCTGGACGCTCAGGGCGTCCCGATGGATGCGGCCGCGGTCGCGGCGGCCAGCGCCGCCAAGGAAGAGA
CGGTCACCGACCTGCTGAAGCTCGACGACCTCAAGCTCGAGATGGGCTACGCGCTCCTCGCCCTGGTCAACGGCGAGGGC
CAGGACCGGCTCACCGACCAGATCAAGGCCCTGCGCCGCCAGCTCGCCGCGGAACTGGGCTTCGTGATGCCGTCGGTGCG
CATCCTCGACAACGTCCAGCTCGACGCCAACGCCTACGTGGTCCGGGTCAAGGAGATCGAGGCGGGCACCGGCCGGATCT
TCCCGGGCCAGTTCATGGCGATGGACCCGATGGGCGGTCAGGTTCAGCTGCCCGGGCAGCACATGCTGGAGCCGACCTTC
GGCCTGCCGGCGACCTGGATCGACGCGGCCCTGCGCGACCAGGCCCAGCTCAAGGGCTACACCGTGGTCGATGCCGCCAC
CGTCGTGTCGACGCATCTCACCGAGGTCATCAAGGCTCACGTCTCCGAGCTCCTCAACCACGTCGAGGTCTCGAAGCTGC
TCCGCGAGCTGCCCAAGGAGCACGCCGAGCTGCTCAAGGAGATCGTGCCGTCGCAGATCTCCACCACCGGCATCCAGCGC
GTGCTGCAGTTCCTGCTCGCCGAGCGGGTCTCGATCCGCGATCTCGGGGCGATCGTGGAGGCGGTCGCCGAGGTGGCGGG
CGCCGTGAAGAACCCCCGCGACGTCGTCGAGCACGTCCGGGCACGCCTGGGCCGGCAGATCTGCGCGCAGTACCAGGATC
CGAACGGCATGCTGCCGATCATCACCCTGTCGCCGGCCTGGGAGCAGGCGTTCATGGAGTCGATCGTGGGCGAGCGCGAG
GAGCGCTACCTCGCGATGCAGCCTTCGAAGCTCAGCGAGTTCGTCAACACCGTGCGCGACCGCTTCGAGACGGCGGCGCG
CCAGGGCGAGATGCCGGTGCTGGTCACCTCGGCCCAGACGCGCCCCTTCGTGCGCTCGATCATCGAGCGCTTCCGCCGCG
AGACGCCGGTGATGAGCCAGGCGGAGATCCACCCGCGGGCGCGGCTGCGGACGGTGAACTCGATCTGA

Upstream 100 bases:

>100_bases
ACCGTCGGCCGCATCTTAACGCCGCGCTAACCATCCGGTCGGCAGATCTTGCCGGGTACGTCCCGGTCGCGTCCCGGGTG
AGCGGCAGCGGGTGGCATCG

Downstream 100 bases:

>100_bases
GGATCGACCGGCCGCGGCGCCGGCGCTCTGCCGGGGCCGCCGCAGCCGCCACGTGGGCCCTCAGAGGCATCGGCGCGAAC
CGCGCGCGCACGCGGCAAGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MAETASAPAQTGAAAVLGQLTLPTRGDLQALSKRSDLLFATGVLGILAVLIFPLPAILLDLLLAVSIIMSVLIMMTGLSI
DNPLEFTVFPTLLLIATMLRLALNLASTRLILGHGHEGTAAAGHVIEAFGHFVMGGNFVIGIIVFAILIIVNFVVITKGS
GRIAEVAARFTLDAMPGKQMAIDADLSAGLIDEKAAKARRAALEEESSFFGAMDGASKFVRGDAVAALLITFINVVGGII
IGVAQQGLSFGEAAKSYTLLTIGDGLASQVPALIVSTAAGLLVSKAGVRGAADKALGKQLAHYPKALGMSAAVMLLIALL
PGMPMLPFVLLGGGAGYAAWRINKTAKLAPPLDAQGVPMDAAAVAAASAAKEETVTDLLKLDDLKLEMGYALLALVNGEG
QDRLTDQIKALRRQLAAELGFVMPSVRILDNVQLDANAYVVRVKEIEAGTGRIFPGQFMAMDPMGGQVQLPGQHMLEPTF
GLPATWIDAALRDQAQLKGYTVVDAATVVSTHLTEVIKAHVSELLNHVEVSKLLRELPKEHAELLKEIVPSQISTTGIQR
VLQFLLAERVSIRDLGAIVEAVAEVAGAVKNPRDVVEHVRARLGRQICAQYQDPNGMLPIITLSPAWEQAFMESIVGERE
ERYLAMQPSKLSEFVNTVRDRFETAARQGEMPVLVTSAQTRPFVRSIIERFRRETPVMSQAEIHPRARLRTVNSI

Sequences:

>Translated_715_residues
MAETASAPAQTGAAAVLGQLTLPTRGDLQALSKRSDLLFATGVLGILAVLIFPLPAILLDLLLAVSIIMSVLIMMTGLSI
DNPLEFTVFPTLLLIATMLRLALNLASTRLILGHGHEGTAAAGHVIEAFGHFVMGGNFVIGIIVFAILIIVNFVVITKGS
GRIAEVAARFTLDAMPGKQMAIDADLSAGLIDEKAAKARRAALEEESSFFGAMDGASKFVRGDAVAALLITFINVVGGII
IGVAQQGLSFGEAAKSYTLLTIGDGLASQVPALIVSTAAGLLVSKAGVRGAADKALGKQLAHYPKALGMSAAVMLLIALL
PGMPMLPFVLLGGGAGYAAWRINKTAKLAPPLDAQGVPMDAAAVAAASAAKEETVTDLLKLDDLKLEMGYALLALVNGEG
QDRLTDQIKALRRQLAAELGFVMPSVRILDNVQLDANAYVVRVKEIEAGTGRIFPGQFMAMDPMGGQVQLPGQHMLEPTF
GLPATWIDAALRDQAQLKGYTVVDAATVVSTHLTEVIKAHVSELLNHVEVSKLLRELPKEHAELLKEIVPSQISTTGIQR
VLQFLLAERVSIRDLGAIVEAVAEVAGAVKNPRDVVEHVRARLGRQICAQYQDPNGMLPIITLSPAWEQAFMESIVGERE
ERYLAMQPSKLSEFVNTVRDRFETAARQGEMPVLVTSAQTRPFVRSIIERFRRETPVMSQAEIHPRARLRTVNSI
>Mature_714_residues
AETASAPAQTGAAAVLGQLTLPTRGDLQALSKRSDLLFATGVLGILAVLIFPLPAILLDLLLAVSIIMSVLIMMTGLSID
NPLEFTVFPTLLLIATMLRLALNLASTRLILGHGHEGTAAAGHVIEAFGHFVMGGNFVIGIIVFAILIIVNFVVITKGSG
RIAEVAARFTLDAMPGKQMAIDADLSAGLIDEKAAKARRAALEEESSFFGAMDGASKFVRGDAVAALLITFINVVGGIII
GVAQQGLSFGEAAKSYTLLTIGDGLASQVPALIVSTAAGLLVSKAGVRGAADKALGKQLAHYPKALGMSAAVMLLIALLP
GMPMLPFVLLGGGAGYAAWRINKTAKLAPPLDAQGVPMDAAAVAAASAAKEETVTDLLKLDDLKLEMGYALLALVNGEGQ
DRLTDQIKALRRQLAAELGFVMPSVRILDNVQLDANAYVVRVKEIEAGTGRIFPGQFMAMDPMGGQVQLPGQHMLEPTFG
LPATWIDAALRDQAQLKGYTVVDAATVVSTHLTEVIKAHVSELLNHVEVSKLLRELPKEHAELLKEIVPSQISTTGIQRV
LQFLLAERVSIRDLGAIVEAVAEVAGAVKNPRDVVEHVRARLGRQICAQYQDPNGMLPIITLSPAWEQAFMESIVGEREE
RYLAMQPSKLSEFVNTVRDRFETAARQGEMPVLVTSAQTRPFVRSIIERFRRETPVMSQAEIHPRARLRTVNSI

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=673, Percent_Identity=42.6448736998514, Blast_Score=518, Evalue=1e-148,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 76192; Mature: 76061

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETASAPAQTGAAAVLGQLTLPTRGDLQALSKRSDLLFATGVLGILAVLIFPLPAILLD
CCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLLAVSIIMSVLIMMTGLSIDNPLEFTVFPTLLLIATMLRLALNLASTRLILGHGHEGTA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCH
AAGHVIEAFGHFVMGGNFVIGIIVFAILIIVNFVVITKGSGRIAEVAARFTLDAMPGKQM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCE
AIDADLSAGLIDEKAAKARRAALEEESSFFGAMDGASKFVRGDAVAALLITFINVVGGII
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVAQQGLSFGEAAKSYTLLTIGDGLASQVPALIVSTAAGLLVSKAGVRGAADKALGKQL
HHHHHHCCCHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AHYPKALGMSAAVMLLIALLPGMPMLPFVLLGGGAGYAAWRINKTAKLAPPLDAQGVPMD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCH
AAAVAAASAAKEETVTDLLKLDDLKLEMGYALLALVNGEGQDRLTDQIKALRRQLAAELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FVMPSVRILDNVQLDANAYVVRVKEIEAGTGRIFPGQFMAMDPMGGQVQLPGQHMLEPTF
HHCCCHHHHHCCEECCCEEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCCHHHCCCCC
GLPATWIDAALRDQAQLKGYTVVDAATVVSTHLTEVIKAHVSELLNHVEVSKLLRELPKE
CCCHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAELLKEIVPSQISTTGIQRVLQFLLAERVSIRDLGAIVEAVAEVAGAVKNPRDVVEHVR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ARLGRQICAQYQDPNGMLPIITLSPAWEQAFMESIVGEREERYLAMQPSKLSEFVNTVRD
HHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHCEEEECCHHHHHHHHHHHH
RFETAARQGEMPVLVTSAQTRPFVRSIIERFRRETPVMSQAEIHPRARLRTVNSI
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHCCC
>Mature Secondary Structure 
AETASAPAQTGAAAVLGQLTLPTRGDLQALSKRSDLLFATGVLGILAVLIFPLPAILLD
CCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLLAVSIIMSVLIMMTGLSIDNPLEFTVFPTLLLIATMLRLALNLASTRLILGHGHEGTA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCH
AAGHVIEAFGHFVMGGNFVIGIIVFAILIIVNFVVITKGSGRIAEVAARFTLDAMPGKQM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCE
AIDADLSAGLIDEKAAKARRAALEEESSFFGAMDGASKFVRGDAVAALLITFINVVGGII
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVAQQGLSFGEAAKSYTLLTIGDGLASQVPALIVSTAAGLLVSKAGVRGAADKALGKQL
HHHHHHCCCHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AHYPKALGMSAAVMLLIALLPGMPMLPFVLLGGGAGYAAWRINKTAKLAPPLDAQGVPMD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCH
AAAVAAASAAKEETVTDLLKLDDLKLEMGYALLALVNGEGQDRLTDQIKALRRQLAAELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FVMPSVRILDNVQLDANAYVVRVKEIEAGTGRIFPGQFMAMDPMGGQVQLPGQHMLEPTF
HHCCCHHHHHCCEECCCEEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCCHHHCCCCC
GLPATWIDAALRDQAQLKGYTVVDAATVVSTHLTEVIKAHVSELLNHVEVSKLLRELPKE
CCCHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAELLKEIVPSQISTTGIQRVLQFLLAERVSIRDLGAIVEAVAEVAGAVKNPRDVVEHVR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ARLGRQICAQYQDPNGMLPIITLSPAWEQAFMESIVGEREERYLAMQPSKLSEFVNTVRD
HHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHCEEEECCHHHHHHHHHHHH
RFETAARQGEMPVLVTSAQTRPFVRSIIERFRRETPVMSQAEIHPRARLRTVNSI
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938923; 1732219; 11259647 [H]