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The map label for this gene is ctrA [H]

Identifier: 170751941

GI number: 170751941

Start: 5892551

End: 5893252

Strand: Reverse

Name: ctrA [H]

Synonym: Mrad2831_5573

Alternate gene names: 170751941

Gene position: 5893252-5892551 (Counterclockwise)

Preceding gene: 170751945

Following gene: 170751938

Centisome position: 96.96

GC content: 62.96

Gene sequence:

>702_bases
ATGCGGGTACTTTTGATCGAGGACGACAGCGCGACCGCGCAGAGCATCGAGCTGATGCTCAAGTCCGAGAACTTCAACAC
CTACACCACCGACCTCGGGGAAGAGGGTGTCGATCTCGGCAAGCTGTACGACTACGACATCATCCTCCTCGATCTGAACC
TGCCCGATATGTCGGGCTACGAGGTGCTCCGCTCGCTGCGCGTGGCGAAGGTGAAGACCCCGATCCTGATCCTGTCCGGC
ATGGCCGGCATCGAGGACAAGGTGAAGGGCCTCGGCTTCGGCGCCGACGACTACCTCACCAAGCCGTTCCACAAGGACGA
GCTGGTGGCGCGCATCCACGCCATCGTGCGCCGCTCGAAGGGCCACGCCCAGTCGGTCATCACCACCGGCGACCTGATCG
TGAACCTCGATCAGAAGACCGTCGAGGTCGGCGGCGCCCGGGTGCACCTCACCGGCAAGGAGTACCAGATGCTGGAACTC
CTCTCGCTCCGGAAGGGCACGACCCTCACCAAGGAGATGTTCCTCAACCATCTCTACGGCGGCATGGACGAGCCCGAGTT
GAAGATCATCGACGTCTTCATCTGCAAGCTGCGCAAGAAGCTCGCGAACGCCAGCCAGGGCAAGAACTACATCGAGACCG
TCTGGGGCCGCGGCTACGTGCTGCGCGAGCCGATGGACGGCGAGGAGCGCATGGCGGTCTGA

Upstream 100 bases:

>100_bases
CCACGTCAAGAGCGACGGAGCGCCCGTCCACAGGCCGGTGGCGGGCGAAGGCTGGGACGTGTCTGCGCGCTGATGCGGCC
GGCGGGGCTGGGGACCGACG

Downstream 100 bases:

>100_bases
TCCGCCGGTCGCACCGTCCCGTGAAAAACCCCGCGCGGTCCGGCCGCGCGGGGTTTTCGCGTTCCGGCGGTGTCCGAAGC
CCTCACCGCGTCCCGGTGGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRVLLIEDDSATAQSIELMLKSENFNTYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRSLRVAKVKTPILILSG
MAGIEDKVKGLGFGADDYLTKPFHKDELVARIHAIVRRSKGHAQSVITTGDLIVNLDQKTVEVGGARVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASQGKNYIETVWGRGYVLREPMDGEERMAV

Sequences:

>Translated_233_residues
MRVLLIEDDSATAQSIELMLKSENFNTYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRSLRVAKVKTPILILSG
MAGIEDKVKGLGFGADDYLTKPFHKDELVARIHAIVRRSKGHAQSVITTGDLIVNLDQKTVEVGGARVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASQGKNYIETVWGRGYVLREPMDGEERMAV
>Mature_233_residues
MRVLLIEDDSATAQSIELMLKSENFNTYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRSLRVAKVKTPILILSG
MAGIEDKVKGLGFGADDYLTKPFHKDELVARIHAIVRRSKGHAQSVITTGDLIVNLDQKTVEVGGARVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASQGKNYIETVWGRGYVLREPMDGEERMAV

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=36.6071428571429, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=36.6812227074236, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.5291479820628, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.0316742081448, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.6363636363636, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.0175438596491, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.1369863013699, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.0748898678414, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=30.4545454545455, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.2792792792793, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.1101321585903, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=24.375, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=25.1063829787234, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26107; Mature: 26107

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSATAQSIELMLKSENFNTYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHEEEEEECCCCCEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRSLRVAKVKTPILILSGMAGIEDKVKGLGFGADDYLTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHCC
GHAQSVITTGDLIVNLDQKTVEVGGARVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHEEEECCEEEECCHHEEEECCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASQGKNYIETVWGRGYVLREPMDGEERMAV
CCCCCCHHHHHHHHHHHHHHHCCHHCCCHHHHHHCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MRVLLIEDDSATAQSIELMLKSENFNTYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHEEEEEECCCCCEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRSLRVAKVKTPILILSGMAGIEDKVKGLGFGADDYLTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHCC
GHAQSVITTGDLIVNLDQKTVEVGGARVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHEEEECCEEEECCHHEEEECCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASQGKNYIETVWGRGYVLREPMDGEERMAV
CCCCCCHHHHHHHHHHHHHHHCCHHCCCHHHHHHCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA