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The map label for this gene is bdlA [H]

Identifier: 170751899

GI number: 170751899

Start: 5848866

End: 5850341

Strand: Reverse

Name: bdlA [H]

Synonym: Mrad2831_5531

Alternate gene names: 170751899

Gene position: 5850341-5848866 (Counterclockwise)

Preceding gene: 170751901

Following gene: 170751895

Centisome position: 96.26

GC content: 72.29

Gene sequence:

>1476_bases
ATGGCGATGTTTGGTTCACGCGACGACGCCCTGCTCGCGGCGATCGACCGGACGATGGCGCGGGTCGAGTTCGACCTCGA
CGGCACCGTCACCGACGCGAACGCGCTGTTCCTCGACCTTCTGGGCTACACGCTCGACGAGGTGCGCGGCCAGCACCACC
GGGTGTTCGTTCCGGAGGACGACCGCGCGGGCCAGGACTACGCCGCGTTCTGGGACCGGCTGCGCGCCGGCCAGCACGAG
GCCCGCGCCTTCCGCCGCGTCGCGAAGTCCGGCGAGGTCGTCTGGATCCAGGGCTCGTACAACCCGATCCTCGACCGGCG
CGGCCGGCCGACCAAGGTCGTCAAGCTCGCCACCGACATCACCGAGGAGCGCGCCCGCAACGCCCGCCACGCCGGTCAGA
TCGCGGCGCTCGACCGCTCACAGGCGGTGATCACCTTCGCCCTCGACGGGACGATCACGGACGCCAACGCCAACTTCCTG
TCCACCATGGGTTACACCCTCGAGGAGATCCGCGGGCGGCATCACCGGATGTTCCTGCCGCAGGCCGAGGCGGCGAGCGC
CGGCTACGCGGCGTTCTGGGCCGCCCTCGGCAACGGCGAGTATCAGGCCGGCGAGTTCCGGCGGATCGGGAAGGGCGGCC
GCACCGTCTGGATCTTCGGCGCCTACAACCCGATCCTCGACGCCGACGGCAGGCCCTGCGCCGTCGTCAAGTTCGCCACC
GACGTCACCCGTCAGGTCGAGGATCGGCAGCGCCGGGCCGAGGGCCAGCGCGCCATCGACGCCGACATCGCGGCGATCCG
CGACTCGATGAGCCGGGTTGTCAGGCAGGCCGACGACACCGCCGAGTCTTCGAGCCAGACCGCGCGGAACGTCGAGGCGG
TCGCCGCCGGCTCCGAGGAATTCGCCGCCTCCATCGAGGAGCTGAGCCGCCACGCCCTGCAGGCGAAATCGTCGGTGGAC
CTCGTGGTCACCCGCGCCGAGGAGGCGGGGGCGATCGTCGTGGGCCTGACCGGTGCCGCCGACCGGATCGGGGCGGCGGT
GAGCCTGATCCGCTCCATCGCCGACCAGACGAATCTCCTCGCGCTGAACGCCACCATCGAGGCGGCCCGCGCCGGGGTCG
CCGGCAAGGGCTTCGCCGTCGTCGCCGCCGAGGTGAAGGCGCTCGCCGAGCAGACCGCCAAGGCGACCGGCGAGATCGGC
ACCCAGATCGCCGCCGTGCAGGCCGAGACCTCCCGGGCCGTGGCGGCGATCGACGGGATCGGCGCCACGATCGAGCAGCT
CAGCGCGATCTCCCTGAGCGTGTCGTCCGCCGTCACCGAGCAGGCCGCGGTGACCCGCGACATGACCGAGAACATGCAGT
CCGCCGCGCAGAGCGTCGCCGCCGTCCACGCCGCCATGGCGGAGATCGCGGCCTCGGCGGGCGTGGTCGACGCCTCGGTC
CGCAAGGTCTCGGAAGCCGCCCGCGCCCTCGCGTGA

Upstream 100 bases:

>100_bases
CGACCGCTCGCACCCCGGCGAGAACATGCCATTGACGGATTTTTAAGCGCGTCCCCCTATGATCGTCACCACTCTACAGA
TCAGGCGGGCACAGGCTCCG

Downstream 100 bases:

>100_bases
GCGGCCCGCGCCCGCCTCAGGCGGCGCGGGTCGCGGCGGGCTCCGCCACGGCGACCCGGTCGCGCCCGCCGTTCTTGGCG
ACGTAGAGGGCGGTGTCGGC

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MAMFGSRDDALLAAIDRTMARVEFDLDGTVTDANALFLDLLGYTLDEVRGQHHRVFVPEDDRAGQDYAAFWDRLRAGQHE
ARAFRRVAKSGEVVWIQGSYNPILDRRGRPTKVVKLATDITEERARNARHAGQIAALDRSQAVITFALDGTITDANANFL
STMGYTLEEIRGRHHRMFLPQAEAASAGYAAFWAALGNGEYQAGEFRRIGKGGRTVWIFGAYNPILDADGRPCAVVKFAT
DVTRQVEDRQRRAEGQRAIDADIAAIRDSMSRVVRQADDTAESSSQTARNVEAVAAGSEEFAASIEELSRHALQAKSSVD
LVVTRAEEAGAIVVGLTGAADRIGAAVSLIRSIADQTNLLALNATIEAARAGVAGKGFAVVAAEVKALAEQTAKATGEIG
TQIAAVQAETSRAVAAIDGIGATIEQLSAISLSVSSAVTEQAAVTRDMTENMQSAAQSVAAVHAAMAEIAASAGVVDASV
RKVSEAARALA

Sequences:

>Translated_491_residues
MAMFGSRDDALLAAIDRTMARVEFDLDGTVTDANALFLDLLGYTLDEVRGQHHRVFVPEDDRAGQDYAAFWDRLRAGQHE
ARAFRRVAKSGEVVWIQGSYNPILDRRGRPTKVVKLATDITEERARNARHAGQIAALDRSQAVITFALDGTITDANANFL
STMGYTLEEIRGRHHRMFLPQAEAASAGYAAFWAALGNGEYQAGEFRRIGKGGRTVWIFGAYNPILDADGRPCAVVKFAT
DVTRQVEDRQRRAEGQRAIDADIAAIRDSMSRVVRQADDTAESSSQTARNVEAVAAGSEEFAASIEELSRHALQAKSSVD
LVVTRAEEAGAIVVGLTGAADRIGAAVSLIRSIADQTNLLALNATIEAARAGVAGKGFAVVAAEVKALAEQTAKATGEIG
TQIAAVQAETSRAVAAIDGIGATIEQLSAISLSVSSAVTEQAAVTRDMTENMQSAAQSVAAVHAAMAEIAASAGVVDASV
RKVSEAARALA
>Mature_490_residues
AMFGSRDDALLAAIDRTMARVEFDLDGTVTDANALFLDLLGYTLDEVRGQHHRVFVPEDDRAGQDYAAFWDRLRAGQHEA
RAFRRVAKSGEVVWIQGSYNPILDRRGRPTKVVKLATDITEERARNARHAGQIAALDRSQAVITFALDGTITDANANFLS
TMGYTLEEIRGRHHRMFLPQAEAASAGYAAFWAALGNGEYQAGEFRRIGKGGRTVWIFGAYNPILDADGRPCAVVKFATD
VTRQVEDRQRRAEGQRAIDADIAAIRDSMSRVVRQADDTAESSSQTARNVEAVAAGSEEFAASIEELSRHALQAKSSVDL
VVTRAEEAGAIVVGLTGAADRIGAAVSLIRSIADQTNLLALNATIEAARAGVAGKGFAVVAAEVKALAEQTAKATGEIGT
QIAAVQAETSRAVAAIDGIGATIEQLSAISLSVSSAVTEQAAVTRDMTENMQSAAQSVAAVHAAMAEIAASAGVVDASVR
KVSEAARALA

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=198, Percent_Identity=34.8484848484849, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367378, Length=147, Percent_Identity=36.734693877551, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788195, Length=128, Percent_Identity=38.28125, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787690, Length=128, Percent_Identity=36.71875, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788194, Length=137, Percent_Identity=37.2262773722628, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 52026; Mature: 51895

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMFGSRDDALLAAIDRTMARVEFDLDGTVTDANALFLDLLGYTLDEVRGQHHRVFVPED
CCCCCCCCCHHHHHHHHHHHHEEECCCCCEECHHHHHHHHHHHHHHHHCCCCCEEECCCC
DRAGQDYAAFWDRLRAGQHEARAFRRVAKSGEVVWIQGSYNPILDRRGRPTKVVKLATDI
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCCEEEHHHHH
TEERARNARHAGQIAALDRSQAVITFALDGTITDANANFLSTMGYTLEEIRGRHHRMFLP
HHHHHHHHHHCCCEEEECCCCEEEEEEECCEEECCCCHHHHHHCCHHHHHCCCHHEEECC
QAEAASAGYAAFWAALGNGEYQAGEFRRIGKGGRTVWIFGAYNPILDADGRPCAVVKFAT
CHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEHH
DVTRQVEDRQRRAEGQRAIDADIAAIRDSMSRVVRQADDTAESSSQTARNVEAVAAGSEE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
FAASIEELSRHALQAKSSVDLVVTRAEEAGAIVVGLTGAADRIGAAVSLIRSIADQTNLL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEE
ALNATIEAARAGVAGKGFAVVAAEVKALAEQTAKATGEIGTQIAAVQAETSRAVAAIDGI
EEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHC
GATIEQLSAISLSVSSAVTEQAAVTRDMTENMQSAAQSVAAVHAAMAEIAASAGVVDASV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RKVSEAARALA
HHHHHHHHHCC
>Mature Secondary Structure 
AMFGSRDDALLAAIDRTMARVEFDLDGTVTDANALFLDLLGYTLDEVRGQHHRVFVPED
CCCCCCCCHHHHHHHHHHHHEEECCCCCEECHHHHHHHHHHHHHHHHCCCCCEEECCCC
DRAGQDYAAFWDRLRAGQHEARAFRRVAKSGEVVWIQGSYNPILDRRGRPTKVVKLATDI
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCCEEEHHHHH
TEERARNARHAGQIAALDRSQAVITFALDGTITDANANFLSTMGYTLEEIRGRHHRMFLP
HHHHHHHHHHCCCEEEECCCCEEEEEEECCEEECCCCHHHHHHCCHHHHHCCCHHEEECC
QAEAASAGYAAFWAALGNGEYQAGEFRRIGKGGRTVWIFGAYNPILDADGRPCAVVKFAT
CHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEHH
DVTRQVEDRQRRAEGQRAIDADIAAIRDSMSRVVRQADDTAESSSQTARNVEAVAAGSEE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
FAASIEELSRHALQAKSSVDLVVTRAEEAGAIVVGLTGAADRIGAAVSLIRSIADQTNLL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEE
ALNATIEAARAGVAGKGFAVVAAEVKALAEQTAKATGEIGTQIAAVQAETSRAVAAIDGI
EEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHC
GATIEQLSAISLSVSSAVTEQAAVTRDMTENMQSAAQSVAAVHAAMAEIAASAGVVDASV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RKVSEAARALA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]