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The map label for this gene is fecD [C]

Identifier: 170751889

GI number: 170751889

Start: 5835570

End: 5836595

Strand: Reverse

Name: fecD [C]

Synonym: Mrad2831_5521

Alternate gene names: 170751889

Gene position: 5836595-5835570 (Counterclockwise)

Preceding gene: 170751890

Following gene: 170751888

Centisome position: 96.03

GC content: 74.37

Gene sequence:

>1026_bases
ATGATCCGGGCGCGCGCCCGACGCCGCCTGCCCGCTGCGCTGTTGTCCGGGCTCGCCCTGCTGGCGCTGACCGCCCTCGC
GCTGGCTGTCGGCAAGTACCCGGTCGCGCCCGCGGACCTCGCCGCCATCCTCGGGAACCGGCTGCTCGGGCTGCCGGCCC
GGGCCCCGGCGACGGCGGAGACGGTCGTGATGCAGGTGCGCCTGCCGCGGGTGATCGCCGCGCTGGTCGTGGGCGCGGCC
CTCTCGGCGGCGGGGGCGACCTACCAGGGCCTGTTCCGCAACCCGCTGGTCTCGCCCGACATCCTCGGCGTCTCGGCCGG
CGCCGGGCTCGGGGCCGTGCTCGGGATCTATCTCGGCCTGCCGGTGGCCCCGATCCAGGCCCTGGCCTTCCTGGGCGGGC
TCGGCGCCGTCGCGGCGGTCTACGGCGTCGGCCTCGCCGTGCGGCGGCACGATCCAGTCCTGACCCTGGTCCTGGCCGGG
GTCGCGGTGGGGGCGGTGCTCGGGGCTGGCATCTCGCTCCTCAAGGTCCTGGCCGATCCCTACAACCAGCTGCCGGCGAT
CACGTTCTGGCTCCTCGGCAGCCTGTCCTCGGTCACCCTCGGCGACGTCGCCGCCACCCTGCCGATGATGCTGCTCGGCC
TCGTGCCCCTGGTGCTCCTGCGCTGGCGCATGAACCTGATGAGTCTCGGCGACGCGGAAGCGCGGGCCCTCGGTGTGGAA
ACTCGGTTGCTCCGTCCCGTCCTGATCGCCGGCGCGACCCTGATCACGGCGGCGGCCGTGGCGATGACCGGGGTCATCGG
CTGGATCGGGCTGATCGTGCCGCACGTCGCTCGGCTCCTGGTCGGGCCGGATTACCGCCGCCTGCTGCCGGCCTCGCTGG
TGCTCGGCGCGGGCTACCTGGTGCTGGTCGACCTGATCGCGCGGAATCTGGGCACCGTCGAGGTGCCCCTCGGCATCCTG
ACGGCGCTCGTGGGGGCGCCGTTCTTCCTCTGGCTGCTGGCGTCCGGGCGCCGGGGCTTCAGCTGA

Upstream 100 bases:

>100_bases
ACGTCGACCTCGATGCCGGTCAGGTCGCCGCTCTCCTCGCCCCGACACCGGGCTCGGCCCCGGGCCCGGCCCGGCGAGCC
GCGTCCCGGCCGCCGCCGTG

Downstream 100 bases:

>100_bases
TGCTGCTCCAGGTCCGGGACCTCGCCGTCGGGTACGGCGGCCGCACGGCCGGCCGCACCGTCGCCCAGGGCGTGTCGTTC
GACCTCGCCGCGGGCGAGGT

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MIRARARRRLPAALLSGLALLALTALALAVGKYPVAPADLAAILGNRLLGLPARAPATAETVVMQVRLPRVIAALVVGAA
LSAAGATYQGLFRNPLVSPDILGVSAGAGLGAVLGIYLGLPVAPIQALAFLGGLGAVAAVYGVGLAVRRHDPVLTLVLAG
VAVGAVLGAGISLLKVLADPYNQLPAITFWLLGSLSSVTLGDVAATLPMMLLGLVPLVLLRWRMNLMSLGDAEARALGVE
TRLLRPVLIAGATLITAAAVAMTGVIGWIGLIVPHVARLLVGPDYRRLLPASLVLGAGYLVLVDLIARNLGTVEVPLGIL
TALVGAPFFLWLLASGRRGFS

Sequences:

>Translated_341_residues
MIRARARRRLPAALLSGLALLALTALALAVGKYPVAPADLAAILGNRLLGLPARAPATAETVVMQVRLPRVIAALVVGAA
LSAAGATYQGLFRNPLVSPDILGVSAGAGLGAVLGIYLGLPVAPIQALAFLGGLGAVAAVYGVGLAVRRHDPVLTLVLAG
VAVGAVLGAGISLLKVLADPYNQLPAITFWLLGSLSSVTLGDVAATLPMMLLGLVPLVLLRWRMNLMSLGDAEARALGVE
TRLLRPVLIAGATLITAAAVAMTGVIGWIGLIVPHVARLLVGPDYRRLLPASLVLGAGYLVLVDLIARNLGTVEVPLGIL
TALVGAPFFLWLLASGRRGFS
>Mature_341_residues
MIRARARRRLPAALLSGLALLALTALALAVGKYPVAPADLAAILGNRLLGLPARAPATAETVVMQVRLPRVIAALVVGAA
LSAAGATYQGLFRNPLVSPDILGVSAGAGLGAVLGIYLGLPVAPIQALAFLGGLGAVAAVYGVGLAVRRHDPVLTLVLAG
VAVGAVLGAGISLLKVLADPYNQLPAITFWLLGSLSSVTLGDVAATLPMMLLGLVPLVLLRWRMNLMSLGDAEARALGVE
TRLLRPVLIAGATLITAAAVAMTGVIGWIGLIVPHVARLLVGPDYRRLLPASLVLGAGYLVLVDLIARNLGTVEVPLGIL
TALVGAPFFLWLLASGRRGFS

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=278, Percent_Identity=42.0863309352518, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788004, Length=290, Percent_Identity=37.9310344827586, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790741, Length=294, Percent_Identity=35.3741496598639, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786805, Length=287, Percent_Identity=40.0696864111498, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786804, Length=229, Percent_Identity=37.5545851528384, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=32.7526132404181, Blast_Score=98, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34796; Mature: 34796

Theoretical pI: Translated: 11.73; Mature: 11.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRARARRRLPAALLSGLALLALTALALAVGKYPVAPADLAAILGNRLLGLPARAPATAE
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHH
TVVMQVRLPRVIAALVVGAALSAAGATYQGLFRNPLVSPDILGVSAGAGLGAVLGIYLGL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCC
PVAPIQALAFLGGLGAVAAVYGVGLAVRRHDPVLTLVLAGVAVGAVLGAGISLLKVLADP
CHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
YNQLPAITFWLLGSLSSVTLGDVAATLPMMLLGLVPLVLLRWRMNLMSLGDAEARALGVE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TRLLRPVLIAGATLITAAAVAMTGVIGWIGLIVPHVARLLVGPDYRRLLPASLVLGAGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VLVDLIARNLGTVEVPLGILTALVGAPFFLWLLASGRRGFS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRARARRRLPAALLSGLALLALTALALAVGKYPVAPADLAAILGNRLLGLPARAPATAE
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHH
TVVMQVRLPRVIAALVVGAALSAAGATYQGLFRNPLVSPDILGVSAGAGLGAVLGIYLGL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCC
PVAPIQALAFLGGLGAVAAVYGVGLAVRRHDPVLTLVLAGVAVGAVLGAGISLLKVLADP
CHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
YNQLPAITFWLLGSLSSVTLGDVAATLPMMLLGLVPLVLLRWRMNLMSLGDAEARALGVE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TRLLRPVLIAGATLITAAAVAMTGVIGWIGLIVPHVARLLVGPDYRRLLPASLVLGAGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VLVDLIARNLGTVEVPLGILTALVGAPFFLWLLASGRRGFS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]