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The map label for this gene is ubiA [H]

Identifier: 170751752

GI number: 170751752

Start: 5690797

End: 5691744

Strand: Reverse

Name: ubiA [H]

Synonym: Mrad2831_5382

Alternate gene names: 170751752

Gene position: 5691744-5690797 (Counterclockwise)

Preceding gene: 170751753

Following gene: 170751750

Centisome position: 93.65

GC content: 72.89

Gene sequence:

>948_bases
ATGAACGGCACGGTGTTTGACGACGGGCGGCCGGCCGATGCCGTCTCCGGGCACTGGGTCGACCGGCGGGCGCCCCGACC
CTGGCGCCCGTACCTGCGCCTGGCCCGGATCGACAGGCCGATCGGCTGGTGGCTCCTCCTCCTCCCCTGCTGGTGGTCGG
CCGCCCTGGCGGCGATCGCCGCGGACCAGGCCTTTCCCGATCCCTGGCACTGCCTCCTGTTCCTGATCGGCGCGGTCGCG
ATGCGCGGGGCGGGCTCGACCTACAACGACATCGCCGACCGCGACCTCGACGCGCAGGTCGAGCGCACGCGCCTGCGCCC
CCTGCCCTCCGGGCAGGTGCGGCCGCGCCACGCGGCCCTGTTCCTGGTGATCCAGGCCCTGATCGGGCTCGCCGTCCTGC
TGCAGTTCAACGCGGAGGCGGTGGTCATCGGCCTGTGCTCGCTGCTGCCGGTGGCGATCTACCCGTTCATGAAACGGGTC
ATGCCGATGCCGCAGGCCATCTTGGGCCTGGCCTTCGCCTGGGGCGCGCTGATGGGCTGGGCCGCGGTGTTCGCCCGCCT
CGACCCGCCGGCGCTCCTGCTCTACGCGGGCGCCCTGTGCTGGGTGATCGGCTACGACACGATCTACGCGGTGCAGGATA
TCGAGGACGACGAGATCGCGGGGATTCGCTCCTCGGCCCGCCTGTTCGGCCGGCACGTGCGGCTCGCCGTCGGGCTGTGC
TACGCGCTGGCGGCGCTGTTCGTAGTGCTGGCGGCGCGCGGGGCCGGAGCGGGGCCCGTCGGGTATCTGGGGATCGCCGC
CTTCGCCGGGCATCTCGCCTGGCAGGTCCTGTCGCTGCGCGAGCGCGACGGGCGCGGTGCTCTGACGCTGTTCCGGTCGA
ACCGGGATGCGGGCCTGATCCTGTTCGTCGGCCTCACCGCCGACGCGCTGCTGCGCAACCTGGCCTAG

Upstream 100 bases:

>100_bases
GGGCGCTCTCTGAGATCGTCTGAGAGGATCACGGATCCGGCGCGGGTCCCCCTCTGCAGCGGCGGGGATTTCACGTGCGG
GACGACCGGAGATCCGACCG

Downstream 100 bases:

>100_bases
GCGCGGGCGGCGCCCTCAGGTGCGGGCGATGATCTCGTTCTCGCCGCGGAAGATCTGCGGGCGCGCCGGCAGCCGGCCGG
TCTTGCGGCGGGCCAGGAAG

Product: 4-hydroxybenzoate polyprenyl transferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNGTVFDDGRPADAVSGHWVDRRAPRPWRPYLRLARIDRPIGWWLLLLPCWWSAALAAIAADQAFPDPWHCLLFLIGAVA
MRGAGSTYNDIADRDLDAQVERTRLRPLPSGQVRPRHAALFLVIQALIGLAVLLQFNAEAVVIGLCSLLPVAIYPFMKRV
MPMPQAILGLAFAWGALMGWAAVFARLDPPALLLYAGALCWVIGYDTIYAVQDIEDDEIAGIRSSARLFGRHVRLAVGLC
YALAALFVVLAARGAGAGPVGYLGIAAFAGHLAWQVLSLRERDGRGALTLFRSNRDAGLILFVGLTADALLRNLA

Sequences:

>Translated_315_residues
MNGTVFDDGRPADAVSGHWVDRRAPRPWRPYLRLARIDRPIGWWLLLLPCWWSAALAAIAADQAFPDPWHCLLFLIGAVA
MRGAGSTYNDIADRDLDAQVERTRLRPLPSGQVRPRHAALFLVIQALIGLAVLLQFNAEAVVIGLCSLLPVAIYPFMKRV
MPMPQAILGLAFAWGALMGWAAVFARLDPPALLLYAGALCWVIGYDTIYAVQDIEDDEIAGIRSSARLFGRHVRLAVGLC
YALAALFVVLAARGAGAGPVGYLGIAAFAGHLAWQVLSLRERDGRGALTLFRSNRDAGLILFVGLTADALLRNLA
>Mature_315_residues
MNGTVFDDGRPADAVSGHWVDRRAPRPWRPYLRLARIDRPIGWWLLLLPCWWSAALAAIAADQAFPDPWHCLLFLIGAVA
MRGAGSTYNDIADRDLDAQVERTRLRPLPSGQVRPRHAALFLVIQALIGLAVLLQFNAEAVVIGLCSLLPVAIYPFMKRV
MPMPQAILGLAFAWGALMGWAAVFARLDPPALLLYAGALCWVIGYDTIYAVQDIEDDEIAGIRSSARLFGRHVRLAVGLC
YALAALFVVLAARGAGAGPVGYLGIAAFAGHLAWQVLSLRERDGRGALTLFRSNRDAGLILFVGLTADALLRNLA

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=284, Percent_Identity=41.9014084507042, Blast_Score=202, Evalue=3e-52,
Organism=Escherichia coli, GI1790473, Length=277, Percent_Identity=35.3790613718412, Blast_Score=151, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17553718, Length=297, Percent_Identity=39.3939393939394, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI32565247, Length=296, Percent_Identity=36.4864864864865, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17553720, Length=206, Percent_Identity=39.8058252427184, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI32565245, Length=146, Percent_Identity=43.1506849315069, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=145, Percent_Identity=42.7586206896552, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=293, Percent_Identity=36.8600682593857, Blast_Score=169, Evalue=7e-43,
Organism=Drosophila melanogaster, GI21355567, Length=288, Percent_Identity=44.7916666666667, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34243; Mature: 34243

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTVFDDGRPADAVSGHWVDRRAPRPWRPYLRLARIDRPIGWWLLLLPCWWSAALAAIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ADQAFPDPWHCLLFLIGAVAMRGAGSTYNDIADRDLDAQVERTRLRPLPSGQVRPRHAAL
HHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHH
FLVIQALIGLAVLLQFNAEAVVIGLCSLLPVAIYPFMKRVMPMPQAILGLAFAWGALMGW
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AAVFARLDPPALLLYAGALCWVIGYDTIYAVQDIEDDEIAGIRSSARLFGRHVRLAVGLC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
YALAALFVVLAARGAGAGPVGYLGIAAFAGHLAWQVLSLRERDGRGALTLFRSNRDAGLI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
LFVGLTADALLRNLA
EEECCCHHHHHHHCC
>Mature Secondary Structure
MNGTVFDDGRPADAVSGHWVDRRAPRPWRPYLRLARIDRPIGWWLLLLPCWWSAALAAIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ADQAFPDPWHCLLFLIGAVAMRGAGSTYNDIADRDLDAQVERTRLRPLPSGQVRPRHAAL
HHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHH
FLVIQALIGLAVLLQFNAEAVVIGLCSLLPVAIYPFMKRVMPMPQAILGLAFAWGALMGW
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AAVFARLDPPALLLYAGALCWVIGYDTIYAVQDIEDDEIAGIRSSARLFGRHVRLAVGLC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
YALAALFVVLAARGAGAGPVGYLGIAAFAGHLAWQVLSLRERDGRGALTLFRSNRDAGLI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
LFVGLTADALLRNLA
EEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA