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The map label for this gene is cysQ [H]

Identifier: 170751750

GI number: 170751750

Start: 5689089

End: 5689904

Strand: Reverse

Name: cysQ [H]

Synonym: Mrad2831_5380

Alternate gene names: 170751750

Gene position: 5689904-5689089 (Counterclockwise)

Preceding gene: 170751752

Following gene: 170751747

Centisome position: 93.62

GC content: 73.9

Gene sequence:

>816_bases
ATGCCCGAGCCTCTCACCGACGATGCCGTATCCGCCCTGATGCCGGAACTGCGCGCCGTGATGCGCGAGGCCGCCGACAT
CGCCCGGCCCTTCTTCAGGCTCGGCGGTCAGACCTCGGCCCGGATCTGGTCGAAGTCCGGCGGCTCGCCGGTCACCGAGG
CGGACGTCGCGGTCGACGCCTTCCTGAAGGTGCGCCTGAGCGCCCTCGTGCCGCGGGCGGCGTGGCTGTCGGAGGAGACT
GCCGACGACCCGGCCCGCCTCGGCCACGACCTCGTCTGGATCGTCGATCCGATCGACGGGACGCGGGCCTTCCTGTCGGG
CCATCCGGACTGGTCGATCGCGGTGGCGCTCCTGTCGCGCGGCGAGCCGCTGATCGGCTTCGTCCACGCGCCGGTGGGCG
ACGCGGATTACGAGGCCGTGCGCGGGCGCGGCGCGACGCGGAACGGCGAACCGATCCGCGTCGATCCCAGGCAGAGCCTG
CCGGGCGCCCGCATCACCGGCCCGAAGCCGATGCTCGACCGTCTGGCCCGGGGCGCCGGAGAAGACCCGGACTTCGAGGT
GGTCGCGCGGATCCCGTCCCTCGCCCTGCGGCTCGCCCGCGTGGCGGACGGCACGGTCGATATCGGGATGATCTCCGGCA
ATGCCCGCGACTGGGACTTGGCCGCCGCCGACCTGGTTCTCCGCGAGGCGGGCGGCGTGGTCTGCGATTTCTCCGGCGCG
GCGACCCCGTACAATCGCGCCGACCCGGTGCACGGCGAGCTGCTCGCCGCGCCGGTGGGTCTGCGCGACCCGGTCCTCGC
CGCCTGGGAGCGCTGA

Upstream 100 bases:

>100_bases
AGCCCGAGCGGGTGAGCCCAGGCGGGCCCGGACGTCCGCGTCGCCGGACGGGCGGGACGGCGAGGCCCTCGCGGGCCGCA
CGGATTCCACGCGGAGCGCG

Downstream 100 bases:

>100_bases
GGCCGAGGCCTCGGACGACTCCTGAGGAAGGAGCCGCGGACGGCTCAGGCCGCCGCGGTCTCGCGGATCCTCACCGCGGC
GGGCGCGAGCCCGAGACGCT

Product: inositol monophosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MPEPLTDDAVSALMPELRAVMREAADIARPFFRLGGQTSARIWSKSGGSPVTEADVAVDAFLKVRLSALVPRAAWLSEET
ADDPARLGHDLVWIVDPIDGTRAFLSGHPDWSIAVALLSRGEPLIGFVHAPVGDADYEAVRGRGATRNGEPIRVDPRQSL
PGARITGPKPMLDRLARGAGEDPDFEVVARIPSLALRLARVADGTVDIGMISGNARDWDLAAADLVLREAGGVVCDFSGA
ATPYNRADPVHGELLAAPVGLRDPVLAAWER

Sequences:

>Translated_271_residues
MPEPLTDDAVSALMPELRAVMREAADIARPFFRLGGQTSARIWSKSGGSPVTEADVAVDAFLKVRLSALVPRAAWLSEET
ADDPARLGHDLVWIVDPIDGTRAFLSGHPDWSIAVALLSRGEPLIGFVHAPVGDADYEAVRGRGATRNGEPIRVDPRQSL
PGARITGPKPMLDRLARGAGEDPDFEVVARIPSLALRLARVADGTVDIGMISGNARDWDLAAADLVLREAGGVVCDFSGA
ATPYNRADPVHGELLAAPVGLRDPVLAAWER
>Mature_270_residues
PEPLTDDAVSALMPELRAVMREAADIARPFFRLGGQTSARIWSKSGGSPVTEADVAVDAFLKVRLSALVPRAAWLSEETA
DDPARLGHDLVWIVDPIDGTRAFLSGHPDWSIAVALLSRGEPLIGFVHAPVGDADYEAVRGRGATRNGEPIRVDPRQSLP
GARITGPKPMLDRLARGAGEDPDFEVVARIPSLALRLARVADGTVDIGMISGNARDWDLAAADLVLREAGGVVCDFSGAA
TPYNRADPVHGELLAAPVGLRDPVLAAWER

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=215, Percent_Identity=32.5581395348837, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI221625487, Length=199, Percent_Identity=27.1356783919598, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031789, Length=199, Percent_Identity=27.1356783919598, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1788882, Length=240, Percent_Identity=29.1666666666667, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790659, Length=135, Percent_Identity=31.8518518518519, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193202570, Length=216, Percent_Identity=30.5555555555556, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320493, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357329, Length=199, Percent_Identity=31.6582914572864, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664926, Length=203, Percent_Identity=31.0344827586207, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24664922, Length=213, Percent_Identity=30.0469483568075, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357303, Length=196, Percent_Identity=31.1224489795918, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664918, Length=195, Percent_Identity=29.7435897435897, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357957, Length=201, Percent_Identity=27.363184079602, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28814; Mature: 28683

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEPLTDDAVSALMPELRAVMREAADIARPFFRLGGQTSARIWSKSGGSPVTEADVAVDA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHH
FLKVRLSALVPRAAWLSEETADDPARLGHDLVWIVDPIDGTRAFLSGHPDWSIAVALLSR
HHHHHHHHHCCHHHHHCCCCCCCHHHCCCCEEEEEECCCCCHHHHCCCCCHHHHHHHHHC
GEPLIGFVHAPVGDADYEAVRGRGATRNGEPIRVDPRQSLPGARITGPKPMLDRLARGAG
CCCEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCHHCCCCCCCCCCHHHHHHHHHCCC
EDPDFEVVARIPSLALRLARVADGTVDIGMISGNARDWDLAAADLVLREAGGVVCDFSGA
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCC
ATPYNRADPVHGELLAAPVGLRDPVLAAWER
CCCCCCCCCCCCHHEECCCCCCCCHHHHCCC
>Mature Secondary Structure 
PEPLTDDAVSALMPELRAVMREAADIARPFFRLGGQTSARIWSKSGGSPVTEADVAVDA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHH
FLKVRLSALVPRAAWLSEETADDPARLGHDLVWIVDPIDGTRAFLSGHPDWSIAVALLSR
HHHHHHHHHCCHHHHHCCCCCCCHHHCCCCEEEEEECCCCCHHHHCCCCCHHHHHHHHHC
GEPLIGFVHAPVGDADYEAVRGRGATRNGEPIRVDPRQSLPGARITGPKPMLDRLARGAG
CCCEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCHHCCCCCCCCCCHHHHHHHHHCCC
EDPDFEVVARIPSLALRLARVADGTVDIGMISGNARDWDLAAADLVLREAGGVVCDFSGA
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCC
ATPYNRADPVHGELLAAPVGLRDPVLAAWER
CCCCCCCCCCCCHHEECCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]