Click here to switch to the map view.

The map label for this gene is cycZ [H]

Identifier: 170751712

GI number: 170751712

Start: 5651073

End: 5651870

Strand: Reverse

Name: cycZ [H]

Synonym: Mrad2831_5342

Alternate gene names: 170751712

Gene position: 5651870-5651073 (Counterclockwise)

Preceding gene: 170751715

Following gene: 170751711

Centisome position: 92.99

GC content: 70.3

Gene sequence:

>798_bases
ATGACGCCCTCCCTCTGGACCCGCCTGTCGAACCCCAGCCACTTCATGCGGTGGTCGGGGGCGCTGGTGCCGTGGCTGAC
GGTCCTGTCCCTCGGCGTCCTGACGCTGGGCCTGTACCAGACCTTCTTCGTGGTGCCGCCCGACTACCAGCAGGGCGAGA
CCGTGCGGATCATGTACATCCACGTGCCGGCGGCGTGGCTCGGCGTGTTCTTCTACGGCGCGATGAGCGTGTCGGCGATC
GGCACCCTGGTGTGGCGCCACCCGCTCGCCGACGTCGCTCAGCGGGCAGCCGCGCCGATCGGGGCCGCCTTCACGCTGAT
CTGCCTCGTGACCGGCTCGCTGTGGGGCAAGCCCATGTGGGGCACCTACTGGGTCTGGGACGCGCGCCTGACCTCCATGC
TGATCCTGCTGCTGATCTACTGCGGCATCATCGCCCTGTGGCGGACCCTGGAGGATCCGAACCGCGCGGCGCGCGCCGTG
GCGATCCTGACGCTCGTCGGCGCCGTGAACCTGCCGATCATCAAGTTCTCGGTGAACTGGTGGTCGACCCTGCACCAGCC
GGCCTCGATCCTGCGCATGGGCGGCTCGACCATCGACCCCTCGATGCTCCACCCGCTGCTGGTCATGATCGGCGCCGCGA
CCCTCGGCGGCATGACGCTGCACCTCTACGCGATGCGCACCGAGATCATGCGCCGCCGGGTGCGGACGCTGACGATCCGC
GAGGCCGAGCGCCTCGACCGCGCCCAGCCGCGCCTCACCCCGACACCGGCCGCGATGCCGGTCGGGCAGCCGGTCTAG

Upstream 100 bases:

>100_bases
TCCATCCCGTAGACCGCGCCGCCTGCGCCGCCGACCCGCATTGTTGCTGCACCGCACCCTAGGCTAGACCGCTTCCACGA
TGTCCGAGACAGCTGCCGCG

Downstream 100 bases:

>100_bases
GAGGACCGCGATGGATCTCGGGTCTCACGGCGGCTTCATCCTGGCCGCCTACGCCTTCACGGCCTTGGTGATGGTCGCCC
TGGTGGGCAACGCCCTGCGC

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTPSLWTRLSNPSHFMRWSGALVPWLTVLSLGVLTLGLYQTFFVVPPDYQQGETVRIMYIHVPAAWLGVFFYGAMSVSAI
GTLVWRHPLADVAQRAAAPIGAAFTLICLVTGSLWGKPMWGTYWVWDARLTSMLILLLIYCGIIALWRTLEDPNRAARAV
AILTLVGAVNLPIIKFSVNWWSTLHQPASILRMGGSTIDPSMLHPLLVMIGAATLGGMTLHLYAMRTEIMRRRVRTLTIR
EAERLDRAQPRLTPTPAAMPVGQPV

Sequences:

>Translated_265_residues
MTPSLWTRLSNPSHFMRWSGALVPWLTVLSLGVLTLGLYQTFFVVPPDYQQGETVRIMYIHVPAAWLGVFFYGAMSVSAI
GTLVWRHPLADVAQRAAAPIGAAFTLICLVTGSLWGKPMWGTYWVWDARLTSMLILLLIYCGIIALWRTLEDPNRAARAV
AILTLVGAVNLPIIKFSVNWWSTLHQPASILRMGGSTIDPSMLHPLLVMIGAATLGGMTLHLYAMRTEIMRRRVRTLTIR
EAERLDRAQPRLTPTPAAMPVGQPV
>Mature_264_residues
TPSLWTRLSNPSHFMRWSGALVPWLTVLSLGVLTLGLYQTFFVVPPDYQQGETVRIMYIHVPAAWLGVFFYGAMSVSAIG
TLVWRHPLADVAQRAAAPIGAAFTLICLVTGSLWGKPMWGTYWVWDARLTSMLILLLIYCGIIALWRTLEDPNRAARAVA
ILTLVGAVNLPIIKFSVNWWSTLHQPASILRMGGSTIDPSMLHPLLVMIGAATLGGMTLHLYAMRTEIMRRRVRTLTIRE
AERLDRAQPRLTPTPAAMPVGQPV

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=242, Percent_Identity=47.5206611570248, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 29444; Mature: 29313

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSLWTRLSNPSHFMRWSGALVPWLTVLSLGVLTLGLYQTFFVVPPDYQQGETVRIMYI
CCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEE
HVPAAWLGVFFYGAMSVSAIGTLVWRHPLADVAQRAAAPIGAAFTLICLVTGSLWGKPMW
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GTYWVWDARLTSMLILLLIYCGIIALWRTLEDPNRAARAVAILTLVGAVNLPIIKFSVNW
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECHH
WSTLHQPASILRMGGSTIDPSMLHPLLVMIGAATLGGMTLHLYAMRTEIMRRRVRTLTIR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAERLDRAQPRLTPTPAAMPVGQPV
HHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPSLWTRLSNPSHFMRWSGALVPWLTVLSLGVLTLGLYQTFFVVPPDYQQGETVRIMYI
CCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEE
HVPAAWLGVFFYGAMSVSAIGTLVWRHPLADVAQRAAAPIGAAFTLICLVTGSLWGKPMW
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GTYWVWDARLTSMLILLLIYCGIIALWRTLEDPNRAARAVAILTLVGAVNLPIIKFSVNW
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECHH
WSTLHQPASILRMGGSTIDPSMLHPLLVMIGAATLGGMTLHLYAMRTEIMRRRVRTLTIR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAERLDRAQPRLTPTPAAMPVGQPV
HHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]