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The map label for this gene is cycY [H]

Identifier: 170751710

GI number: 170751710

Start: 5650308

End: 5650922

Strand: Reverse

Name: cycY [H]

Synonym: Mrad2831_5340

Alternate gene names: 170751710

Gene position: 5650922-5650308 (Counterclockwise)

Preceding gene: 170751711

Following gene: 170751707

Centisome position: 92.98

GC content: 73.66

Gene sequence:

>615_bases
ATGACCGCCCCCCTCGACGACACCGCCGGCCGGACGCCACCGGTCCGCCGCTCGCTGCTGCTGATCCTGCCGGCGCTCGT
CTTCGCGGCGCTCGCCGCCGTGCTGTTCCTGCGCCTGCGCTCCGGCGCCGACCCGGCCGCCCTGCCCTCCGCGATGATCG
GCAAGCCGGTGCCGCGCTTCGACCTGCCCGCCGTGCCGGGACTGACCGCCAACGGCGCGCCCGTACCCGGGCTGTCGAGC
GCGGACCTCAAGGGCCAGATCACGGTGCTCAACGTCTTCGCCTCGTGGTGCGCGCCCTGCCAGGTGGAGCACCCGATGCT
GATGCGGCTGGCGAAGGAACCCGGCATCCGGCTCGTCGGCATCGACTACAAGGAGCCGACGCCCGAGGCCGGCCAGCGCT
TCCTGACCCGGCACGGCGTTCCGTTCAGCGCGGTGGGCGCCGATGCCGGCGGCCGCGCGGCGATCGATTTCGGCGTCTAC
GGCGTGCCCGAGACCTTCATCATCGGGCCCGACGGCGTGATCCGCGACAAGCTGGTCGGCATCCTCACGCCGGAGAACTT
CGCGAGCGTGCTCGCGCGGATCCGCGCCGCCGGGAAGGTGGCGGCCGCGCAGTAG

Upstream 100 bases:

>100_bases
ACGCCTTCACGGCCTTGGTGATGGTCGCCCTGGTGGGCAACGCCCTGCGCGACCGCCGCGCGCAGCGCCGCGCCCTCAAG
GGGTTCGGCGAGGACCGGCG

Downstream 100 bases:

>100_bases
GCGTCAGGCCTCCGGCTGCGCCTTCTTGCGCTCGTAGCGGGTGAGCAGCGGCGTCTGCGCGAGGGCGAACAGCACGGTGA
TCGGCATGATGCCGAACACC

Product: periplasmic protein thiol--disulfide oxidoreductase DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTAPLDDTAGRTPPVRRSLLLILPALVFAALAAVLFLRLRSGADPAALPSAMIGKPVPRFDLPAVPGLTANGAPVPGLSS
ADLKGQITVLNVFASWCAPCQVEHPMLMRLAKEPGIRLVGIDYKEPTPEAGQRFLTRHGVPFSAVGADAGGRAAIDFGVY
GVPETFIIGPDGVIRDKLVGILTPENFASVLARIRAAGKVAAAQ

Sequences:

>Translated_204_residues
MTAPLDDTAGRTPPVRRSLLLILPALVFAALAAVLFLRLRSGADPAALPSAMIGKPVPRFDLPAVPGLTANGAPVPGLSS
ADLKGQITVLNVFASWCAPCQVEHPMLMRLAKEPGIRLVGIDYKEPTPEAGQRFLTRHGVPFSAVGADAGGRAAIDFGVY
GVPETFIIGPDGVIRDKLVGILTPENFASVLARIRAAGKVAAAQ
>Mature_203_residues
TAPLDDTAGRTPPVRRSLLLILPALVFAALAAVLFLRLRSGADPAALPSAMIGKPVPRFDLPAVPGLTANGAPVPGLSSA
DLKGQITVLNVFASWCAPCQVEHPMLMRLAKEPGIRLVGIDYKEPTPEAGQRFLTRHGVPFSAVGADAGGRAAIDFGVYG
VPETFIIGPDGVIRDKLVGILTPENFASVLARIRAAGKVAAAQ

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=196, Percent_Identity=37.2448979591837, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21219; Mature: 21088

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLDDTAGRTPPVRRSLLLILPALVFAALAAVLFLRLRSGADPAALPSAMIGKPVPRF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCC
DLPAVPGLTANGAPVPGLSSADLKGQITVLNVFASWCAPCQVEHPMLMRLAKEPGIRLVG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEE
IDYKEPTPEAGQRFLTRHGVPFSAVGADAGGRAAIDFGVYGVPETFIIGPDGVIRDKLVG
ECCCCCCHHHHHHHHHHCCCCCEECCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHE
ILTPENFASVLARIRAAGKVAAAQ
EECCHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
TAPLDDTAGRTPPVRRSLLLILPALVFAALAAVLFLRLRSGADPAALPSAMIGKPVPRF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCC
DLPAVPGLTANGAPVPGLSSADLKGQITVLNVFASWCAPCQVEHPMLMRLAKEPGIRLVG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEE
IDYKEPTPEAGQRFLTRHGVPFSAVGADAGGRAAIDFGVYGVPETFIIGPDGVIRDKLVG
ECCCCCCHHHHHHHHHHCCCCCEECCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHE
ILTPENFASVLARIRAAGKVAAAQ
EECCHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]