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The map label for this gene is atoS [C]

Identifier: 170751600

GI number: 170751600

Start: 5537500

End: 5539611

Strand: Reverse

Name: atoS [C]

Synonym: Mrad2831_5221

Alternate gene names: 170751600

Gene position: 5539611-5537500 (Counterclockwise)

Preceding gene: 170751601

Following gene: 170751599

Centisome position: 91.14

GC content: 65.91

Gene sequence:

>2112_bases
ATGTCGGGTAGCCGCGACTTCCTCGCCGGGGCGGGCGAGATGGCGACGCTGATGCGCGCCTACGACTGGACCACGACGCC
GCTCGGTGAGCCCGAGGGTTGGCCCTCCGGCCTGCGCACGGCGGTGCGTCTGCTGCTGAATAGCCACCACCCCATGCACA
TCTTCTGGGGGCCCGAAGCGACATTCTTCTACAACGACGCCTTCGTGCCTTCGGCGGGACCGGAACGCCATCCTTCCGTG
CTTGGCCGTCCAGCTTCCGAAACCTGGGGTGAAATCTGGCCGGTGATCGCCTCCGAGGTCGCCAAGGTCCGGAACGGTGG
CGGGCATACGTGGTACGAGGACCGGCACGTCCCGATCATGCGGCACGGCCGTCTTGAAGATGCGTACTGGACCTACGGGT
TCAGTCCGATCGACGATGACACTGCCCCCGGCGGCATCGGCGGGGTCATCTCGATCCTGACCGAGACCACCAAGCGTAAG
GCGTTGGAGGACAGTCTCCGCGCCAGCGACCGGCGCCATCGCGACCTGTTGCGACAAATGCCCGGCTTCGTCGCGGTTCT
GACCGGTCCCACACACGTTTACGAATACGTCAACGACGCCTACGTGACGATAGCCGGTCAGCGCAGCTTCCTGGGGCACA
GTGTACGCGAGGTGTTCCCTGACCTCGTAGGACAAGGCTTCTTCGAGTTGCTCGACGGAGTCTACGCGACCGGCGAGCCG
TTCTTAGCCAGAGGTATCCCGATCCGCCTCGGCGGTGAGGACGAAGACCGCTTCATCGATCTCCTGTATCACCCGATCCG
TAACGACGACGGCGTGGTCACAGGGATCTTCGTCGGCGGCTACGATGTCACCGTCCAGAACCGCGCAACGGTCGCGTTGC
ACGAACTCAACGAGACACTCGAACAACGGGTAGCCGAGCGGTCGGCCGTACTGTCAGAGACCGAGGAGAGGCTGCGCCAG
TCCCAGAAGATGGAGGCGATCGGCCAACTGACCGGCGGCGTCGCGCACGATTTCAACAACCTGCTGACGATCATCCGCTC
TTCGGTGGACTTCCTGCGCCGTCCGGAGCTGCCGGAAGCACGCAAGGTGCGCTACCTCGACGCCGTCTCCGAAACCGTTG
ACCGGGCCGCCAAGCTCACCGGCCAGCTCCTCGCCTTTGCACGCCGCCAGTCGCTCAAGCCCGAGATCTTCGACGTCGGC
AGCAAGCTGCGCGGGATCGCGGACATGCTCGACACCGTGACCGGCGCGCGGGTGCATGTGACTGTGGACGTGCCTGACGA
ACCCTGCTTCGCGCGTGCCGATCTGAGCCAGTTCGAGACCGCGCTAGTCAACATGGCGGTCAACGCCCGTGACGCGATGG
ACGGTGAAGGCCGCCTGGCCCTGCGCCTCGCCTGCGGGAAGGAGATGCCACAGATCCGTGGGCATGCGGCGTCCCCGGCC
GCCTTCGTGGTGCTGTCGGTCACCGATACCGGCAGCGGTATCGCGCCCGAACAGCTCGCCCGCATCTTCGAGCCATTCTT
CACGACCAAGGAGGTCGGCAAGGGCACCGGCCTCGGCCTGTCCCAGGTGTTCGGGTTCGCCAAACAGTCCGGCGGCGACG
TGAATGTGAGCAGCGTCCTCGGGGAGGGCACGACCTTCACGCTCTATCTGCCCGAGGAGACGAGGGCACCGGCCAGCACG
GCGGGTGGCGATGCCGATGTGCTCGGGTCCCCCGTAGGCGCAGGGCAGCGCGTGCTGGTGGTGGAGGACAACATCGAGGT
CGGCCGGTTCTGCACCCAGATCCTACAGGACCTTGGTTACGTCACCGAGTGGGCCGCCAACGCCGAGGAGGCGCTCGATC
GCCTCGGTGTGGACGGCGGCGGATTCGACGTGGTGTTCTCCGACGTGGTGATGCCCGGCATGGGCGGCGTCGCCCTGGCC
GAAACCCTGCGCGAGCGGCTGCCCGCCCTGCCGGTGGTGCTGGCGTCAGGCTACAGCCACGTGCTCGCCCGCAGGGACGA
CCATGGGTTCGAGCTGTTGCACAAGCCCTACTCGGCCGAACAGCTCGCCCGCATTTTGCAACGGGTCGTCGTGAAACCTT
CAGCCGCTCGTGTGCATCTCCAAGCTCGATGA

Upstream 100 bases:

>100_bases
GAGGTCGTGCGGGCTGCCCTGCGCGAGTTCGAGCGCGCCGAGAGGGGTAAAGCCGCGATGGCGCAGCAGACTCCTCCCTC
TCATGGCCGGTCCTGATCCG

Downstream 100 bases:

>100_bases
TCGACCGCTTTGTTCCGCCCCACCCGGTGTCCGATGCCGACCGCCTGGCGGCCCTCGATGCTTACGGCATCCTTGGTACA
GCCCCGGAACGGACGTTCGA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 703; Mature: 702

Protein sequence:

>703_residues
MSGSRDFLAGAGEMATLMRAYDWTTTPLGEPEGWPSGLRTAVRLLLNSHHPMHIFWGPEATFFYNDAFVPSAGPERHPSV
LGRPASETWGEIWPVIASEVAKVRNGGGHTWYEDRHVPIMRHGRLEDAYWTYGFSPIDDDTAPGGIGGVISILTETTKRK
ALEDSLRASDRRHRDLLRQMPGFVAVLTGPTHVYEYVNDAYVTIAGQRSFLGHSVREVFPDLVGQGFFELLDGVYATGEP
FLARGIPIRLGGEDEDRFIDLLYHPIRNDDGVVTGIFVGGYDVTVQNRATVALHELNETLEQRVAERSAVLSETEERLRQ
SQKMEAIGQLTGGVAHDFNNLLTIIRSSVDFLRRPELPEARKVRYLDAVSETVDRAAKLTGQLLAFARRQSLKPEIFDVG
SKLRGIADMLDTVTGARVHVTVDVPDEPCFARADLSQFETALVNMAVNARDAMDGEGRLALRLACGKEMPQIRGHAASPA
AFVVLSVTDTGSGIAPEQLARIFEPFFTTKEVGKGTGLGLSQVFGFAKQSGGDVNVSSVLGEGTTFTLYLPEETRAPAST
AGGDADVLGSPVGAGQRVLVVEDNIEVGRFCTQILQDLGYVTEWAANAEEALDRLGVDGGGFDVVFSDVVMPGMGGVALA
ETLRERLPALPVVLASGYSHVLARRDDHGFELLHKPYSAEQLARILQRVVVKPSAARVHLQAR

Sequences:

>Translated_703_residues
MSGSRDFLAGAGEMATLMRAYDWTTTPLGEPEGWPSGLRTAVRLLLNSHHPMHIFWGPEATFFYNDAFVPSAGPERHPSV
LGRPASETWGEIWPVIASEVAKVRNGGGHTWYEDRHVPIMRHGRLEDAYWTYGFSPIDDDTAPGGIGGVISILTETTKRK
ALEDSLRASDRRHRDLLRQMPGFVAVLTGPTHVYEYVNDAYVTIAGQRSFLGHSVREVFPDLVGQGFFELLDGVYATGEP
FLARGIPIRLGGEDEDRFIDLLYHPIRNDDGVVTGIFVGGYDVTVQNRATVALHELNETLEQRVAERSAVLSETEERLRQ
SQKMEAIGQLTGGVAHDFNNLLTIIRSSVDFLRRPELPEARKVRYLDAVSETVDRAAKLTGQLLAFARRQSLKPEIFDVG
SKLRGIADMLDTVTGARVHVTVDVPDEPCFARADLSQFETALVNMAVNARDAMDGEGRLALRLACGKEMPQIRGHAASPA
AFVVLSVTDTGSGIAPEQLARIFEPFFTTKEVGKGTGLGLSQVFGFAKQSGGDVNVSSVLGEGTTFTLYLPEETRAPAST
AGGDADVLGSPVGAGQRVLVVEDNIEVGRFCTQILQDLGYVTEWAANAEEALDRLGVDGGGFDVVFSDVVMPGMGGVALA
ETLRERLPALPVVLASGYSHVLARRDDHGFELLHKPYSAEQLARILQRVVVKPSAARVHLQAR
>Mature_702_residues
SGSRDFLAGAGEMATLMRAYDWTTTPLGEPEGWPSGLRTAVRLLLNSHHPMHIFWGPEATFFYNDAFVPSAGPERHPSVL
GRPASETWGEIWPVIASEVAKVRNGGGHTWYEDRHVPIMRHGRLEDAYWTYGFSPIDDDTAPGGIGGVISILTETTKRKA
LEDSLRASDRRHRDLLRQMPGFVAVLTGPTHVYEYVNDAYVTIAGQRSFLGHSVREVFPDLVGQGFFELLDGVYATGEPF
LARGIPIRLGGEDEDRFIDLLYHPIRNDDGVVTGIFVGGYDVTVQNRATVALHELNETLEQRVAERSAVLSETEERLRQS
QKMEAIGQLTGGVAHDFNNLLTIIRSSVDFLRRPELPEARKVRYLDAVSETVDRAAKLTGQLLAFARRQSLKPEIFDVGS
KLRGIADMLDTVTGARVHVTVDVPDEPCFARADLSQFETALVNMAVNARDAMDGEGRLALRLACGKEMPQIRGHAASPAA
FVVLSVTDTGSGIAPEQLARIFEPFFTTKEVGKGTGLGLSQVFGFAKQSGGDVNVSSVLGEGTTFTLYLPEETRAPASTA
GGDADVLGSPVGAGQRVLVVEDNIEVGRFCTQILQDLGYVTEWAANAEEALDRLGVDGGGFDVVFSDVVMPGMGGVALAE
TLRERLPALPVVLASGYSHVLARRDDHGFELLHKPYSAEQLARILQRVVVKPSAARVHLQAR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=32.3651452282158, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=29.5833333333333, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788713, Length=430, Percent_Identity=21.6279069767442, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081816, Length=268, Percent_Identity=29.4776119402985, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=221, Percent_Identity=31.6742081447964, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=25.3164556962025, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=332, Percent_Identity=23.1927710843373, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=29.2576419213974, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76552; Mature: 76421

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSRDFLAGAGEMATLMRAYDWTTTPLGEPEGWPSGLRTAVRLLLNSHHPMHIFWGPEA
CCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCE
TFFYNDAFVPSAGPERHPSVLGRPASETWGEIWPVIASEVAKVRNGGGHTWYEDRHVPIM
EEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
RHGRLEDAYWTYGFSPIDDDTAPGGIGGVISILTETTKRKALEDSLRASDRRHRDLLRQM
CCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGFVAVLTGPTHVYEYVNDAYVTIAGQRSFLGHSVREVFPDLVGQGFFELLDGVYATGEP
CCEEEEECCCHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCHHCCCCC
FLARGIPIRLGGEDEDRFIDLLYHPIRNDDGVVTGIFVGGYDVTVQNRATVALHELNETL
HHHCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCHHHHHHHHHH
EQRVAERSAVLSETEERLRQSQKMEAIGQLTGGVAHDFNNLLTIIRSSVDFLRRPELPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RKVRYLDAVSETVDRAAKLTGQLLAFARRQSLKPEIFDVGSKLRGIADMLDTVTGARVHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
TVDVPDEPCFARADLSQFETALVNMAVNARDAMDGEGRLALRLACGKEMPQIRGHAASPA
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCE
AFVVLSVTDTGSGIAPEQLARIFEPFFTTKEVGKGTGLGLSQVFGFAKQSGGDVNVSSVL
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEHHHHH
GEGTTFTLYLPEETRAPASTAGGDADVLGSPVGAGQRVLVVEDNIEVGRFCTQILQDLGY
CCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
VTEWAANAEEALDRLGVDGGGFDVVFSDVVMPGMGGVALAETLRERLPALPVVLASGYSH
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCHHH
VLARRDDHGFELLHKPYSAEQLARILQRVVVKPSAARVHLQAR
HHHCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure 
SGSRDFLAGAGEMATLMRAYDWTTTPLGEPEGWPSGLRTAVRLLLNSHHPMHIFWGPEA
CCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCE
TFFYNDAFVPSAGPERHPSVLGRPASETWGEIWPVIASEVAKVRNGGGHTWYEDRHVPIM
EEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
RHGRLEDAYWTYGFSPIDDDTAPGGIGGVISILTETTKRKALEDSLRASDRRHRDLLRQM
CCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGFVAVLTGPTHVYEYVNDAYVTIAGQRSFLGHSVREVFPDLVGQGFFELLDGVYATGEP
CCEEEEECCCHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHCCHHCCCCC
FLARGIPIRLGGEDEDRFIDLLYHPIRNDDGVVTGIFVGGYDVTVQNRATVALHELNETL
HHHCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCHHHHHHHHHH
EQRVAERSAVLSETEERLRQSQKMEAIGQLTGGVAHDFNNLLTIIRSSVDFLRRPELPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RKVRYLDAVSETVDRAAKLTGQLLAFARRQSLKPEIFDVGSKLRGIADMLDTVTGARVHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
TVDVPDEPCFARADLSQFETALVNMAVNARDAMDGEGRLALRLACGKEMPQIRGHAASPA
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCE
AFVVLSVTDTGSGIAPEQLARIFEPFFTTKEVGKGTGLGLSQVFGFAKQSGGDVNVSSVL
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEHHHHH
GEGTTFTLYLPEETRAPASTAGGDADVLGSPVGAGQRVLVVEDNIEVGRFCTQILQDLGY
CCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
VTEWAANAEEALDRLGVDGGGFDVVFSDVVMPGMGGVALAETLRERLPALPVVLASGYSH
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCHHH
VLARRDDHGFELLHKPYSAEQLARILQRVVVKPSAARVHLQAR
HHHCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA