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The map label for this gene is aatC [H]

Identifier: 170751454

GI number: 170751454

Start: 5390402

End: 5391631

Strand: Direct

Name: aatC [H]

Synonym: Mrad2831_5073

Alternate gene names: 170751454

Gene position: 5390402-5391631 (Clockwise)

Preceding gene: 170751453

Following gene: 170751455

Centisome position: 88.69

GC content: 68.62

Gene sequence:

>1230_bases
ATGGACACGCCCATGACCGACTTCCACCGCATCAAGCGACTGCCGCCCTACGTCTTCGAGCAGGTCAACCGGATCAAGGC
CGCCGCCCGAGCGCAGGGCGCCGACATCATCGATCTCGGCATGGGCAACCCGGATCTGGACGCCCCGAAGCACGTGATCG
CCAAGCTGTGCGAGACGGCCGGGCGGCCGCGCACGGATCGCTACTCGGCCTCCAAGGGCATCGCGGGCCTGCGCAAGGCC
CAGGCGGGCTATTACCAGCGGCGCTTCGGCGTGACCCTGAACCCCGACACCCAGGTGGTGGCGACCCTCGGGTCGAAGGA
AGGGTTCGCCAACATGGCCCAGGCGATCACCGCGCCGGGCGACGTCGTGCTGGTGCCGAACCCGAGCTACCCGATCCACG
CCTTCGGCTTCCTGATGGCCGGCGGCGTCATCCGCTCCGTGCCGGCCGAGCCGACTCCCGCGATGTTCCCCGCCCTGGAG
CGGGCCATGCGCCACTCGATCCCGAAGCCGGTGGCGCTGGTCGTGTGCTACCCGTCGAACCCGACCGCCTACGTGGCGAG
CCTCGACTTCTATCGGGACCTCGTGGCCTTCGCGAAGCAGCACGAGCTGATCCTGCTGTCGGACCTCGCCTACGCGGAGG
TCTACTTCGACAACAACCCGCCGCCCTCGGTCCTGCAGGTGCCCGGCGCCATCGACTGCACGGTGGAGTTCACCTCGCTG
TCGAAGACCTACTCGATGGCCGGCTGGCGGATGGGCTTCGCGGTGGGCAACGAGCGCCTGCTCGCGGCACTCACCCGGGT
GAAGTCCTACCTCGATTACGGCGCCTTCACGCCGATCCAGGTCGCCGCGACCGCCGCGCTCAACGGGCCGGACGACTGCA
TCCACGAGATGCGCAGCATCTACAGGAAGCGCCGCGACGCGCTGGTGGAATCCTTCGGCAAGGCCGGCTGGACCATCCCG
TCGCCCGCCTCCTCGATGTTCGCCTGGGTCCCGATCCCCGAGCGCTACCGGGAACTGGGCAGCCTCGAATTCTCCAAGCT
GCTGCTGGAGAAGTCCGACGTGGCGGTCGCGCCCGGCATCGGCTTCGGCGAGTTCGGCGACGAGTACGTCCGCATCGCCC
TCGTGGAGAACGAGCAGCGCATCCGGCAGGCGGCACGAAACATCCGACGGTTCTTCGACGGCACCGACAAGACGCTGCAC
AACGTCGTGCCGATGGCCCGGGCCGGGTAG

Upstream 100 bases:

>100_bases
GCCGGCCCTTTTTCTGGGTCGGCGACGGCCCGCAACTCTGCTAGAGCAAGTGGTTCGCCCGACCGGCCCAGACGAGAGAC
GCCGGATCCGGGACGCGCCG

Downstream 100 bases:

>100_bases
CCGGGCCCGCGCAGATTGTTGCCGCGGGGCGACAGACCCGGTCAAAGGTGTCGGCGCCCCGCGCCGGCGCTTGTCAGGGC
GGGGCGCGATGGCCAGGGTC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDTPMTDFHRIKRLPPYVFEQVNRIKAAARAQGADIIDLGMGNPDLDAPKHVIAKLCETAGRPRTDRYSASKGIAGLRKA
QAGYYQRRFGVTLNPDTQVVATLGSKEGFANMAQAITAPGDVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALE
RAMRHSIPKPVALVVCYPSNPTAYVASLDFYRDLVAFAKQHELILLSDLAYAEVYFDNNPPPSVLQVPGAIDCTVEFTSL
SKTYSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIHEMRSIYRKRRDALVESFGKAGWTIP
SPASSMFAWVPIPERYRELGSLEFSKLLLEKSDVAVAPGIGFGEFGDEYVRIALVENEQRIRQAARNIRRFFDGTDKTLH
NVVPMARAG

Sequences:

>Translated_409_residues
MDTPMTDFHRIKRLPPYVFEQVNRIKAAARAQGADIIDLGMGNPDLDAPKHVIAKLCETAGRPRTDRYSASKGIAGLRKA
QAGYYQRRFGVTLNPDTQVVATLGSKEGFANMAQAITAPGDVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALE
RAMRHSIPKPVALVVCYPSNPTAYVASLDFYRDLVAFAKQHELILLSDLAYAEVYFDNNPPPSVLQVPGAIDCTVEFTSL
SKTYSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIHEMRSIYRKRRDALVESFGKAGWTIP
SPASSMFAWVPIPERYRELGSLEFSKLLLEKSDVAVAPGIGFGEFGDEYVRIALVENEQRIRQAARNIRRFFDGTDKTLH
NVVPMARAG
>Mature_409_residues
MDTPMTDFHRIKRLPPYVFEQVNRIKAAARAQGADIIDLGMGNPDLDAPKHVIAKLCETAGRPRTDRYSASKGIAGLRKA
QAGYYQRRFGVTLNPDTQVVATLGSKEGFANMAQAITAPGDVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALE
RAMRHSIPKPVALVVCYPSNPTAYVASLDFYRDLVAFAKQHELILLSDLAYAEVYFDNNPPPSVLQVPGAIDCTVEFTSL
SKTYSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIHEMRSIYRKRRDALVESFGKAGWTIP
SPASSMFAWVPIPERYRELGSLEFSKLLLEKSDVAVAPGIGFGEFGDEYVRIALVENEQRIRQAARNIRRFFDGTDKTLH
NVVPMARAG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=394, Percent_Identity=21.0659898477157, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI169881279, Length=394, Percent_Identity=21.0659898477157, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI56713256, Length=332, Percent_Identity=21.6867469879518, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI56713254, Length=332, Percent_Identity=21.6867469879518, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI169881281, Length=242, Percent_Identity=20.6611570247934, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788722, Length=389, Percent_Identity=51.1568123393316, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1786816, Length=392, Percent_Identity=25.2551020408163, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1788627, Length=239, Percent_Identity=30.1255230125523, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=402, Percent_Identity=22.8855721393035, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=395, Percent_Identity=24.8101265822785, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=395, Percent_Identity=24.8101265822785, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=22.1932114882507, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=326, Percent_Identity=22.3926380368098, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=23.9074550128535, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=23.9074550128535, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=23.9074550128535, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=23.9074550128535, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44890; Mature: 44890

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPMTDFHRIKRLPPYVFEQVNRIKAAARAQGADIIDLGMGNPDLDAPKHVIAKLCETA
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHC
GRPRTDRYSASKGIAGLRKAQAGYYQRRFGVTLNPDTQVVATLGSKEGFANMAQAITAPG
CCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCC
DVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALERAMRHSIPKPVALVVCYPSN
CEEEECCCCCCHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCC
PTAYVASLDFYRDLVAFAKQHELILLSDLAYAEVYFDNNPPPSVLQVPGAIDCTVEFTSL
CCEEEEHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEECCCCEEEEEEECHH
SKTYSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIHEMRSI
HHHHHHCCCEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHH
YRKRRDALVESFGKAGWTIPSPASSMFAWVPIPERYRELGSLEFSKLLLEKSDVAVAPGI
HHHHHHHHHHHHCCCCCCCCCCHHHCEEECCCHHHHHHHCCHHHHHHHHHCCCEEECCCC
GFGEFGDEYVRIALVENEQRIRQAARNIRRFFDGTDKTLHNVVPMARAG
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCC
>Mature Secondary Structure
MDTPMTDFHRIKRLPPYVFEQVNRIKAAARAQGADIIDLGMGNPDLDAPKHVIAKLCETA
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHC
GRPRTDRYSASKGIAGLRKAQAGYYQRRFGVTLNPDTQVVATLGSKEGFANMAQAITAPG
CCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCC
DVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALERAMRHSIPKPVALVVCYPSN
CEEEECCCCCCHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCC
PTAYVASLDFYRDLVAFAKQHELILLSDLAYAEVYFDNNPPPSVLQVPGAIDCTVEFTSL
CCEEEEHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEECCCCEEEEEEECHH
SKTYSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIHEMRSI
HHHHHHCCCEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHH
YRKRRDALVESFGKAGWTIPSPASSMFAWVPIPERYRELGSLEFSKLLLEKSDVAVAPGI
HHHHHHHHHHHHCCCCCCCCCCHHHCEEECCCHHHHHHHCCHHHHHHHHHCCCEEECCCC
GFGEFGDEYVRIALVENEQRIRQAARNIRRFFDGTDKTLHNVVPMARAG
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]