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The map label for this gene is cutA [H]

Identifier: 170751408

GI number: 170751408

Start: 5341751

End: 5342104

Strand: Direct

Name: cutA [H]

Synonym: Mrad2831_5027

Alternate gene names: 170751408

Gene position: 5341751-5342104 (Clockwise)

Preceding gene: 170751405

Following gene: 170751409

Centisome position: 87.89

GC content: 72.03

Gene sequence:

>354_bases
ATGGAGCGTCCGCTCCTCGTCTACACCACCTTCCCCGACCTCGCCTCGGCGATGAACATCGGCGAGGCCCTGGTCCGCGA
GCGTCTCATCGCCTGCATCAACGTGTTCCCGGGCATGCAGTCCGTCTACAGCTGGAAGGGCGCGGTGGAGCGTGGCGCCG
AGGTCGCGGCCATCCTCAAGAGCCGCGAGGGGCTGGCCGACGCGCTGGCGGTCGCGCTGAAGGCGCGCCACCCCTACGAT
ACGCCGATCATCCTGCATCTGCCGGTCGCCGGGGCGGACGCCGACACCGCCGCCTGGATCCTGGCGGAAACGCGGCCCTG
CGGGCCGGCCGGCGCCGGGCCTCAGGCGGACTGA

Upstream 100 bases:

>100_bases
TTCACGTCACGGCTCCAGTCTGGCGAGCGAACCGCCCGGTTGACGTCCTTACCCGGCATGCGCCTCACTCCGCGAGCACA
CGCGCCGACGGAGGCATAGC

Downstream 100 bases:

>100_bases
TCCACCCGACCGAGCCGCGTCGCTTCCGCCCCGGCCGGTCCTGGCAAGGCCCCGGACCGGCGGGCAGACGGCTGTGGACA
AGCGCGCCGCGCCGCCGGTA

Product: CutA1 divalent ion tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MERPLLVYTTFPDLASAMNIGEALVRERLIACINVFPGMQSVYSWKGAVERGAEVAAILKSREGLADALAVALKARHPYD
TPIILHLPVAGADADTAAWILAETRPCGPAGAGPQAD

Sequences:

>Translated_117_residues
MERPLLVYTTFPDLASAMNIGEALVRERLIACINVFPGMQSVYSWKGAVERGAEVAAILKSREGLADALAVALKARHPYD
TPIILHLPVAGADADTAAWILAETRPCGPAGAGPQAD
>Mature_117_residues
MERPLLVYTTFPDLASAMNIGEALVRERLIACINVFPGMQSVYSWKGAVERGAEVAAILKSREGLADALAVALKARHPYD
TPIILHLPVAGADADTAAWILAETRPCGPAGAGPQAD

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526024, Length=93, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=9e-14,
Organism=Homo sapiens, GI62526022, Length=93, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=9e-14,
Organism=Homo sapiens, GI7706244, Length=93, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=9e-14,
Organism=Homo sapiens, GI62198241, Length=93, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI62526026, Length=93, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790579, Length=101, Percent_Identity=39.6039603960396, Blast_Score=80, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32565476, Length=103, Percent_Identity=33.0097087378641, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641937, Length=101, Percent_Identity=29.7029702970297, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12353; Mature: 12353

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERPLLVYTTFPDLASAMNIGEALVRERLIACINVFPGMQSVYSWKGAVERGAEVAAILK
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHH
SREGLADALAVALKARHPYDTPIILHLPVAGADADTAAWILAETRPCGPAGAGPQAD
HCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MERPLLVYTTFPDLASAMNIGEALVRERLIACINVFPGMQSVYSWKGAVERGAEVAAILK
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHH
SREGLADALAVALKARHPYDTPIILHLPVAGADADTAAWILAETRPCGPAGAGPQAD
HCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]