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The map label for this gene is cheB2 [H]

Identifier: 170751203

GI number: 170751203

Start: 5148123

End: 5149208

Strand: Direct

Name: cheB2 [H]

Synonym: Mrad2831_4820

Alternate gene names: 170751203

Gene position: 5148123-5149208 (Clockwise)

Preceding gene: 170751202

Following gene: 170751206

Centisome position: 84.7

GC content: 72.38

Gene sequence:

>1086_bases
GTGAGCGCGTCCCGACCGATCCGCGTCCTCGTGGTCGACGACTCGGCCTCCGTCCGCCAGACCCTGTGCAGCATCCTGGA
GACGGCGCCCGACATCGAGATCCTGGGAACGGCCGCCGATCCGTTCATCGCCGCCCGCCGGATCCAGGAGGAGATCCCGG
ACGTCATCATCCTCGATCTCGAGATGCCCCGCATGGACGGACTGACCTTCCTGCGGAAGATCATGGCGCAGAAGCCGCTC
CCGGTGATCGTCTGCTCGACCCTGACCGGGGCGGGCTCCCGGATGCTGTTCGAGGTCCTGGAGGCGGGGGCCGTCGACGT
GCTGCCGAAGCCGCGGGTCGACACGCGTCAGTTCCTGCTCGAGTCCACCGTCCGGGTCTGCGACGCGGTCCGGGCGGCCG
CGCGGGCCAAGCTGCGCGGGAGCCGGCCGCCCCGGCAGCTGGTCGAGGCGAAGCTCTCGGCCGACGCCGTCCTGCCGCCG
CCCGTCCCCGGTCGCGTGGTGGTCGAGACCGACCGGATCGTCTGCATCGGCGCGTCGACGGGTGGGACGGAGGCCCTGCG
CGACGTGCTCGAGGTGCTGCCCGCCGAGTCCCCCGGCCTCGTCATCGTGCAGCACATGCCGGAGCATTTCACGGCGGCGT
TCGCCAAGCGCCTGAACGGCCTCTGCGCGATCACCGTCAAGGAGGCGGAGGACGGCGATCCCGTGATGCGGGGCCGCGCC
CTGATCGCCCCCGGCGGGCGTCACCTCATGGTCGAGCGCCGGGGCGGCAGCTACGCGGTGTCGGTGAAGGATGGTCCTCT
CGTCGCGCGCCATCGCCCGTCGGTCGACGTCCTGTTCCGGTCGGCCGCCCGGGCGGCGGCCGCGAACGCCCTCGGCATCC
TCCTGACCGGAATGGGCGACGACGGCGCCAATGGCCTGCTGGAGATGCGCCGGGCCGGAGCGCAGACGGTCGCACAGGAC
GAGGCGAGCTGCGTCGTGTTCGGGATGCCCAAGGAAGCGATCGACCGCGGCGCGGCCGCCAAGGTCCTGCCGCTCGAGCA
GATGCACCTGGAGATCCGGCGCTTCGGCCTGTCCGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
ACCTGATCGTCGGCCATTCCGAGTCCATGGCGGGCGTCGGCGTGGCGGGCCTCGACCAGGTCTCCTCCACCGTCTTCAGC
AAGCTGAGGGAATCCAGCCG

Downstream 100 bases:

>100_bases
GGCCGGGGCCGGACTCAGGACGGGTCGCGTTGCCCGGACTGCGCCTCGGCCATCGCCCGGCGCCCGCGCGCGCGGCTGGA
CGGGCGAGCCGCTCCGCGAC

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSASRPIRVLVVDDSASVRQTLCSILETAPDIEILGTAADPFIAARRIQEEIPDVIILDLEMPRMDGLTFLRKIMAQKPL
PVIVCSTLTGAGSRMLFEVLEAGAVDVLPKPRVDTRQFLLESTVRVCDAVRAAARAKLRGSRPPRQLVEAKLSADAVLPP
PVPGRVVVETDRIVCIGASTGGTEALRDVLEVLPAESPGLVIVQHMPEHFTAAFAKRLNGLCAITVKEAEDGDPVMRGRA
LIAPGGRHLMVERRGGSYAVSVKDGPLVARHRPSVDVLFRSAARAAAANALGILLTGMGDDGANGLLEMRRAGAQTVAQD
EASCVVFGMPKEAIDRGAAAKVLPLEQMHLEIRRFGLSAAR

Sequences:

>Translated_361_residues
MSASRPIRVLVVDDSASVRQTLCSILETAPDIEILGTAADPFIAARRIQEEIPDVIILDLEMPRMDGLTFLRKIMAQKPL
PVIVCSTLTGAGSRMLFEVLEAGAVDVLPKPRVDTRQFLLESTVRVCDAVRAAARAKLRGSRPPRQLVEAKLSADAVLPP
PVPGRVVVETDRIVCIGASTGGTEALRDVLEVLPAESPGLVIVQHMPEHFTAAFAKRLNGLCAITVKEAEDGDPVMRGRA
LIAPGGRHLMVERRGGSYAVSVKDGPLVARHRPSVDVLFRSAARAAAANALGILLTGMGDDGANGLLEMRRAGAQTVAQD
EASCVVFGMPKEAIDRGAAAKVLPLEQMHLEIRRFGLSAAR
>Mature_360_residues
SASRPIRVLVVDDSASVRQTLCSILETAPDIEILGTAADPFIAARRIQEEIPDVIILDLEMPRMDGLTFLRKIMAQKPLP
VIVCSTLTGAGSRMLFEVLEAGAVDVLPKPRVDTRQFLLESTVRVCDAVRAAARAKLRGSRPPRQLVEAKLSADAVLPPP
VPGRVVVETDRIVCIGASTGGTEALRDVLEVLPAESPGLVIVQHMPEHFTAAFAKRLNGLCAITVKEAEDGDPVMRGRAL
IAPGGRHLMVERRGGSYAVSVKDGPLVARHRPSVDVLFRSAARAAAANALGILLTGMGDDGANGLLEMRRAGAQTVAQDE
ASCVVFGMPKEAIDRGAAAKVLPLEQMHLEIRRFGLSAAR

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=346, Percent_Identity=50, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38499; Mature: 38368

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASRPIRVLVVDDSASVRQTLCSILETAPDIEILGTAADPFIAARRIQEEIPDVIILDL
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEE
EMPRMDGLTFLRKIMAQKPLPVIVCSTLTGAGSRMLFEVLEAGAVDVLPKPRVDTRQFLL
CCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ESTVRVCDAVRAAARAKLRGSRPPRQLVEAKLSADAVLPPPVPGRVVVETDRIVCIGAST
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCC
GGTEALRDVLEVLPAESPGLVIVQHMPEHFTAAFAKRLNGLCAITVKEAEDGDPVMRGRA
CCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCE
LIAPGGRHLMVERRGGSYAVSVKDGPLVARHRPSVDVLFRSAARAAAANALGILLTGMGD
EECCCCCEEEEEECCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCC
DGANGLLEMRRAGAQTVAQDEASCVVFGMPKEAIDRGAAAKVLPLEQMHLEIRRFGLSAA
CCCHHHHHHHHCCCHHHHCCCCCEEEEECCHHHHCCCCCEEECCHHHHHHHHHHHCCCCC
R
C
>Mature Secondary Structure 
SASRPIRVLVVDDSASVRQTLCSILETAPDIEILGTAADPFIAARRIQEEIPDVIILDL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEE
EMPRMDGLTFLRKIMAQKPLPVIVCSTLTGAGSRMLFEVLEAGAVDVLPKPRVDTRQFLL
CCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ESTVRVCDAVRAAARAKLRGSRPPRQLVEAKLSADAVLPPPVPGRVVVETDRIVCIGAST
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCC
GGTEALRDVLEVLPAESPGLVIVQHMPEHFTAAFAKRLNGLCAITVKEAEDGDPVMRGRA
CCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCE
LIAPGGRHLMVERRGGSYAVSVKDGPLVARHRPSVDVLFRSAARAAAANALGILLTGMGD
EECCCCCEEEEEECCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCC
DGANGLLEMRRAGAQTVAQDEASCVVFGMPKEAIDRGAAAKVLPLEQMHLEIRRFGLSAA
CCCHHHHHHHHCCCHHHHCCCCCEEEEECCHHHHCCCCCEEECCHHHHHHHHHHHCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA